Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "catenin-TCF7L2 complex", which is defined as "A protein complex that contains a catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "beta-catenin-TCF7L2 complex", which is defined as "A protein complex that contains beta-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
GWAS of Bipolar disorder (body mass index interaction)
Description:
Genome-wide association study of bipolar disorder accounting for effect of body mass index. 388 European ancestry cases, 1,020 European ancestry controls
Authors:
Winham SJ, Cuellar-Barboza AB, Oliveros A, McElroy SL, Crow S, Colby C, Choi DS, Chauhan M, Frye M, Biernacka JM
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Bipolar disorder (body mass index interaction). The EFO term bipolar disorder, body mass index was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
SJ Winham, AB Cuellar-Barboza, A Oliveros, SL McElroy, S Crow, C Colby, DS Choi, M Chauhan, M Frye, JM Biernacka
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Type 2 diabetes. The EFO term type II diabetes mellitus was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
M Ghassibe-Sabbagh, M Haber, AK Salloum, Y Al-Sarraj, Y Akle, K Hirbli, J Romanos, F Mouzaya, D Gauguier, DE Platt, H El-Shanti, PA Zalloua
"A protein complex that contains a catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription." [GOC:BHF, GOC:rl, GOC:vk, PMID:14661054]
"A protein complex that contains beta-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription." [GOC:BHF, GOC:rl, PMID:9065401, PMID:9065402]
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Glycated hemoglobin levels. The EFO term A1C measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
CS Franklin, YS Aulchenko, JE Huffman, V Vitart, C Hayward, O Polašek, S Knott, L Zgaga, T Zemunik, I Rudan, H Campbell, AF Wright, SH Wild, JF Wilson
"A protein complex that contains gamma-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription." [GOC:BHF, GOC:vk, PMID:14661054]
"A protein complex that contains gamma-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription." [GOC:BHF, GOC:vk, PMID:14661054]
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Type 2 diabetes. The EFO term type II diabetes mellitus was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Type 2 diabetes. The EFO term type II diabetes mellitus was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
R Sladek, G Rocheleau, J Rung, C Dina, L Shen, D Serre, P Boutin, D Vincent, A Belisle, S Hadjadj, B Balkau, B Heude, G Charpentier, TJ Hudson, A Montpetit, AV Pshezhetsky, M Prentki, BI Posner, DJ Balding, D Meyre, C Polychronakos, P Froguel
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Colorectal cancer. The EFO term colorectal cancer was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
B Zhang, WH Jia, K Matsuda, SS Kweon, K Matsuo, YB Xiang, A Shin, SH Jee, DH Kim, Q Cai, J Long, J Shi, W Wen, G Yang, Y Zhang, C Li, B Li, Y Guo, Z Ren, BT Ji, ZZ Pan, A Takahashi, MH Shin, F Matsuda, YT Gao, JH Oh, S Kim, YO Ahn, AT Chan, J Chang-Claude, ML Slattery, SB Gruber, FR Schumacher, SL Stenzel, G Casey, HR Kim, JY Jeong, JW Park, HL Li, S Hosono, SH Cho, M Kubo, XO Shu, YX Zeng, W Zheng
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Type 2 diabetes. The EFO term type II diabetes mellitus was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
V Steinthorsdottir, G Thorleifsson, I Reynisdottir, R Benediktsson, T Jonsdottir, GB Walters, U Styrkarsdottir, S Gretarsdottir, V Emilsson, S Ghosh, A Baker, S Snorradottir, H Bjarnason, MC Ng, T Hansen, Y Bagger, RL Wilensky, MP Reilly, A Adeyemo, Y Chen, J Zhou, V Gudnason, G Chen, H Huang, K Lashley, A Doumatey, WY So, RC Ma, G Andersen, K Borch-Johnsen, T Jorgensen, JV van Vliet-Ostaptchouk, MH Hofker, C Wijmenga, C Christiansen, DJ Rader, C Rotimi, M Gurney, JC Chan, O Pedersen, G Sigurdsson, JR Gulcher, U Thorsteinsdottir, A Kong, K Stefansson
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Type 2 diabetes. The EFO term type II diabetes mellitus was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
LJ Scott, KL Mohlke, LL Bonnycastle, CJ Willer, Y Li, WL Duren, MR Erdos, HM Stringham, PS Chines, AU Jackson, L Prokunina-Olsson, CJ Ding, AJ Swift, N Narisu, T Hu, R Pruim, R Xiao, XY Li, KN Conneely, NL Riebow, AG Sprau, M Tong, PP White, KN Hetrick, MW Barnhart, CW Bark, JL Goldstein, L Watkins, F Xiang, J Saramies, TA Buchanan, RM Watanabe, TT Valle, L Kinnunen, GR Abecasis, EW Pugh, KF Doheny, RN Bergman, J Tuomilehto, FS Collins, M Boehnke
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Type 2 diabetes. The EFO term type II diabetes mellitus was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JT Salonen, P Uimari, JM Aalto, M Pirskanen, J Kaikkonen, B Todorova, J Hyppönen, VP Korhonen, J Asikainen, C Devine, TP Tuomainen, J Luedemann, M Nauck, W Kerner, RH Stephens, JP New, WE Ollier, JM Gibson, A Payton, MA Horan, N Pendleton, W Mahoney, D Meyre, J Delplanque, P Froguel, O Luzzatto, B Yakir, A Darvasi
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Type 2 diabetes. The EFO term type II diabetes mellitus was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
MC Ng, D Shriner, BH Chen, J Li, WM Chen, X Guo, J Liu, SJ Bielinski, LR Yanek, MA Nalls, ME Comeau, LJ Rasmussen-Torvik, RA Jensen, DS Evans, YV Sun, P An, SR Patel, Y Lu, J Long, LL Armstrong, L Wagenknecht, L Yang, BM Snively, ND Palmer, P Mudgal, CD Langefeld, KL Keene, BI Freedman, JC Mychaleckyj, U Nayak, LJ Raffel, MO Goodarzi, YD Chen, HA Taylor, A Correa, M Sims, D Couper, JS Pankow, E Boerwinkle, A Adeyemo, A Doumatey, G Chen, RA Mathias, D Vaidya, AB Singleton, AB Zonderman, RP Igo, JR Sedor, EK Kabagambe, DS Siscovick, B McKnight, K Rice, Y Liu, WC Hsueh, W Zhao, LF Bielak, A Kraja, MA Province, EP Bottinger, O Gottesman, Q Cai, W Zheng, WJ Blot, WL Lowe, JA Pacheco, DC Crawford, E Grundberg, SS Rich, MG Hayes, XO Shu, RJ Loos, IB Borecki, PA Peyser, SR Cummings, BM Psaty, M Fornage, SK Iyengar, MK Evans, DM Becker, WH Kao, JG Wilson, JI Rotter, MM Sale, S Liu, CN Rotimi, DW Bowden
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Two-hour glucose challenge. The EFO term glucose tolerance test was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
R Saxena, MF Hivert, C Langenberg, T Tanaka, JS Pankow, P Vollenweider, V Lyssenko, N Bouatia-Naji, J Dupuis, AU Jackson, WH Kao, M Li, NL Glazer, AK Manning, J Luan, HM Stringham, I Prokopenko, T Johnson, N Grarup, TW Boesgaard, C Lecoeur, P Shrader, J O'Connell, E Ingelsson, DJ Couper, K Rice, K Song, CH Andreasen, C Dina, A Köttgen, O Le Bacquer, F Pattou, J Taneera, V Steinthorsdottir, D Rybin, K Ardlie, M Sampson, L Qi, M van Hoek, MN Weedon, YS Aulchenko, BF Voight, H Grallert, B Balkau, RN Bergman, SJ Bielinski, A Bonnefond, LL Bonnycastle, K Borch-Johnsen, Y Böttcher, E Brunner, TA Buchanan, SJ Bumpstead, C Cavalcanti-Proença, G Charpentier, YD Chen, PS Chines, FS Collins, M Cornelis, G J Crawford, J Delplanque, A Doney, JM Egan, MR Erdos, M Firmann, NG Forouhi, CS Fox, MO Goodarzi, J Graessler, A Hingorani, B Isomaa, T Jørgensen, M Kivimaki, P Kovacs, K Krohn, M Kumari, T Lauritzen, C Lévy-Marchal, V Mayor, JB McAteer, D Meyre, BD Mitchell, KL Mohlke, MA Morken, N Narisu, CN Palmer, R Pakyz, L Pascoe, F Payne, D Pearson, W Rathmann, A Sandbaek, AA Sayer, LJ Scott, SJ Sharp, E Sijbrands, A Singleton, DS Siscovick, NL Smith, T Sparsø, AJ Swift, H Syddall, G Thorleifsson, A Tönjes, T Tuomi, J Tuomilehto, TT Valle, G Waeber, A Walley, DM Waterworth, E Zeggini, JH Zhao, T Illig, HE Wichmann, JF Wilson, C van Duijn, FB Hu, AD Morris, TM Frayling, AT Hattersley, U Thorsteinsdottir, K Stefansson, P Nilsson, AC Syvänen, AR Shuldiner, M Walker, SR Bornstein, P Schwarz, GH Williams, DM Nathan, J Kuusisto, M Laakso, C Cooper, M Marmot, L Ferrucci, V Mooser, M Stumvoll, RJ Loos, D Altshuler, BM Psaty, JI Rotter, E Boerwinkle, T Hansen, O Pedersen, JC Florez, MI McCarthy, M Boehnke, I Barroso, R Sladek, P Froguel, JB Meigs, L Groop, NJ Wareham, RM Watanabe
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Type 2 diabetes nephropathy. The EFO term type 2 diabetes nephropathy was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
S Maeda, N Osawa, T Hayashi, S Tsukada, M Kobayashi, R Kikkawa
Whole brain expression correlates of ethanol withdrawal in BXD RI mice based on phenotype data in the 1997 Buck et al manuscript. Expression correlates were generated using GeneNetwork.org
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