List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Glaucoma. The EFO term glaucoma was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
KP Burdon, S Macgregor, AW Hewitt, S Sharma, G Chidlow, RA Mills, P Danoy, R Casson, AC Viswanathan, JZ Liu, J Landers, AK Henders, J Wood, E Souzeau, A Crawford, P Leo, JJ Wang, E Rochtchina, DR Nyholt, NG Martin, GW Montgomery, P Mitchell, MA Brown, DA Mackey, JE Craig
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Glioma (high-grade). The EFO term central nervous system cancer was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
M Wrensch, RB Jenkins, JS Chang, RF Yeh, Y Xiao, PA Decker, KV Ballman, M Berger, JC Buckner, S Chang, C Giannini, C Halder, TM Kollmeyer, ML Kosel, DH LaChance, L McCoy, BP O'Neill, J Patoka, AR Pico, M Prados, C Quesenberry, T Rice, AL Rynearson, I Smirnov, T Tihan, J Wiemels, P Yang, JK Wiencke
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Cancer (pleiotropy). The EFO term lung carcinoma, estrogen-receptor negative breast cancer, colorectal cancer, ovarian endometrioid carcinoma, prostate carcinoma, ovarian serous carcinoma, breast carcinoma, ovarian carcinoma, lung adenocarcinoma, squamous cell lung carcinoma was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Type 2 diabetes. The EFO term type II diabetes mellitus was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Myocardial infarction. The EFO term myocardial infarction was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
A Helgadottir, G Thorleifsson, A Manolescu, S Gretarsdottir, T Blondal, A Jonasdottir, A Jonasdottir, A Sigurdsson, A Baker, A Palsson, G Masson, DF Gudbjartsson, KP Magnusson, K Andersen, AI Levey, VM Backman, S Matthiasdottir, T Jonsdottir, S Palsson, H Einarsdottir, S Gunnarsdottir, A Gylfason, V Vaccarino, WC Hooper, MP Reilly, CB Granger, H Austin, DJ Rader, SH Shah, AA Quyyumi, JR Gulcher, G Thorgeirsson, U Thorsteinsdottir, A Kong, K Stefansson
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Nasopharyngeal carcinoma. The EFO term nasopharyngeal neoplasm was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JX Bei, Y Li, WH Jia, BJ Feng, G Zhou, LZ Chen, QS Feng, HQ Low, H Zhang, F He, ES Tai, T Kang, ET Liu, J Liu, YX Zeng
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Vertical cup-disc ratio. The EFO term optic disc size measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
WD Ramdas, LM van Koolwijk, MK Ikram, NM Jansonius, PT de Jong, AA Bergen, A Isaacs, N Amin, YS Aulchenko, RC Wolfs, A Hofman, F Rivadeneira, BA Oostra, AG Uitterlinden, P Hysi, CJ Hammond, HG Lemij, JR Vingerling, CC Klaver, CM van Duijn
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Glaucoma (primary open-angle). The EFO term open-angle glaucoma was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Chronic lymphocytic leukemia. The EFO term chronic lymphocytic leukemia was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
SI Berndt, CF Skibola, V Joseph, NJ Camp, A Nieters, Z Wang, W Cozen, A Monnereau, SS Wang, RS Kelly, Q Lan, LR Teras, N Chatterjee, CC Chung, M Yeager, AR Brooks-Wilson, P Hartge, MP Purdue, BM Birmann, BK Armstrong, P Cocco, Y Zhang, G Severi, A Zeleniuch-Jacquotte, C Lawrence, L Burdette, J Yuenger, A Hutchinson, KB Jacobs, TG Call, TD Shanafelt, AJ Novak, NE Kay, M Liebow, AH Wang, KE Smedby, HO Adami, M Melbye, B Glimelius, ET Chang, M Glenn, K Curtin, LA Cannon-Albright, B Jones, WR Diver, BK Link, GJ Weiner, L Conde, PM Bracci, J Riby, EA Holly, MT Smith, RD Jackson, LF Tinker, Y Benavente, N Becker, P Boffetta, P Brennan, L Foretova, M Maynadie, J McKay, A Staines, KG Rabe, SJ Achenbach, CM Vachon, LR Goldin, SS Strom, MC Lanasa, LG Spector, JF Leis, JM Cunningham, JB Weinberg, VA Morrison, NE Caporaso, AD Norman, MS Linet, AJ De Roos, LM Morton, RK Severson, E Riboli, P Vineis, R Kaaks, D Trichopoulos, G Masala, E Weiderpass, MD Chirlaque, RC Vermeulen, RC Travis, GG Giles, D Albanes, J Virtamo, S Weinstein, J Clavel, T Zheng, TR Holford, K Offit, A Zelenetz, RJ Klein, JJ Spinelli, KA Bertrand, F Laden, E Giovannucci, P Kraft, A Kricker, J Turner, CM Vajdic, MG Ennas, GM Ferri, L Miligi, L Liang, J Sampson, S Crouch, JH Park, KE North, A Cox, JA Snowden, J Wright, A Carracedo, C Lopez-Otin, S Bea, I Salaverria, D Martin-Garcia, E Campo, JF Fraumeni, S de Sanjose, H Hjalgrim, JR Cerhan, SJ Chanock, N Rothman, SL Slager
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Type 2 diabetes. The EFO term type II diabetes mellitus was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
R Saxena, BF Voight, V Lyssenko, NP Burtt, PI de Bakker, H Chen, JJ Roix, S Kathiresan, JN Hirschhorn, MJ Daly, TE Hughes, L Groop, D Altshuler, P Almgren, JC Florez, J Meyer, K Ardlie, K Bengtsson Boström, B Isomaa, G Lettre, U Lindblad, HN Lyon, O Melander, C Newton-Cheh, P Nilsson, M Orho-Melander, L Råstam, EK Speliotes, MR Taskinen, T Tuomi, C Guiducci, A Berglund, J Carlson, L Gianniny, R Hackett, L Hall, J Holmkvist, E Laurila, M Sjögren, M Sterner, A Surti, M Svensson, M Svensson, R Tewhey, B Blumenstiel, M Parkin, M Defelice, R Barry, W Brodeur, J Camarata, N Chia, M Fava, J Gibbons, B Handsaker, C Healy, K Nguyen, C Gates, C Sougnez, D Gage, M Nizzari, SB Gabriel, GW Chirn, Q Ma, H Parikh, D Richardson, D Ricke, S Purcell
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Type 2 diabetes. The EFO term type II diabetes mellitus was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
LJ Scott, KL Mohlke, LL Bonnycastle, CJ Willer, Y Li, WL Duren, MR Erdos, HM Stringham, PS Chines, AU Jackson, L Prokunina-Olsson, CJ Ding, AJ Swift, N Narisu, T Hu, R Pruim, R Xiao, XY Li, KN Conneely, NL Riebow, AG Sprau, M Tong, PP White, KN Hetrick, MW Barnhart, CW Bark, JL Goldstein, L Watkins, F Xiang, J Saramies, TA Buchanan, RM Watanabe, TT Valle, L Kinnunen, GR Abecasis, EW Pugh, KF Doheny, RN Bergman, J Tuomilehto, FS Collins, M Boehnke
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Type 2 diabetes. The EFO term type II diabetes mellitus was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
E Zeggini, MN Weedon, CM Lindgren, TM Frayling, KS Elliott, H Lango, NJ Timpson, JR Perry, NW Rayner, RM Freathy, JC Barrett, B Shields, AP Morris, S Ellard, CJ Groves, LW Harries, JL Marchini, KR Owen, B Knight, LR Cardon, M Walker, GA Hitman, AD Morris, AS Doney, MI McCarthy, AT Hattersley
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Glioma. The EFO term central nervous system cancer was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
S Shete, FJ Hosking, LB Robertson, SE Dobbins, M Sanson, B Malmer, M Simon, Y Marie, B Boisselier, JY Delattre, K Hoang-Xuan, S El Hallani, A Idbaih, D Zelenika, U Andersson, R Henriksson, AT Bergenheim, M Feychting, S Lönn, A Ahlbom, J Schramm, M Linnebank, K Hemminki, R Kumar, SJ Hepworth, A Price, G Armstrong, Y Liu, X Gu, R Yu, C Lau, M Schoemaker, K Muir, A Swerdlow, M Lathrop, M Bondy, RS Houlston
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Glaucoma. The EFO term glaucoma was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
M Takamoto, T Kaburaki, A Mabuchi, M Araie, S Amano, M Aihara, A Tomidokoro, A Iwase, F Mabuchi, K Kashiwagi, S Shirato, N Yasuda, H Kawashima, F Nakajima, J Numaga, Y Kawamura, T Sasaki, K Tokunaga
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Intracranial aneurysm. The EFO term brain aneurysm was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
K Yasuno, K Bilguvar, P Bijlenga, SK Low, B Krischek, G Auburger, M Simon, D Krex, Z Arlier, N Nayak, YM Ruigrok, M Niemelä, A Tajima, M von und zu Fraunberg, T Dóczi, F Wirjatijasa, A Hata, J Blasco, A Oszvald, H Kasuya, G Zilani, B Schoch, P Singh, C Stüer, R Risselada, J Beck, T Sola, F Ricciardi, A Aromaa, T Illig, S Schreiber, CM van Duijn, LH van den Berg, C Perret, C Proust, C Roder, AK Ozturk, E Gaál, D Berg, C Geisen, CM Friedrich, P Summers, AF Frangi, MW State, HE Wichmann, MM Breteler, C Wijmenga, S Mane, L Peltonen, V Elio, MC Sturkenboom, P Lawford, J Byrne, J Macho, EI Sandalcioglu, B Meyer, A Raabe, H Steinmetz, D Rüfenacht, JE Jääskeläinen, J Hernesniemi, GJ Rinkel, H Zembutsu, I Inoue, A Palotie, F Cambien, Y Nakamura, RP Lifton, M Günel
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Oral cavity cancer. The EFO term oral cavity cancer was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Glaucoma (primary open-angle). The EFO term open-angle glaucoma was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
M Nakano, Y Ikeda, Y Tokuda, M Fuwa, N Omi, M Ueno, K Imai, H Adachi, M Kageyama, K Mori, S Kinoshita, K Tashiro
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Coronary heart disease. The EFO term coronary heart disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
X Lu, L Wang, S Chen, L He, X Yang, Y Shi, J Cheng, L Zhang, CC Gu, J Huang, T Wu, Y Ma, J Li, J Cao, J Chen, D Ge, Z Fan, Y Li, L Zhao, H Li, X Zhou, L Chen, D Liu, J Chen, X Duan, Y Hao, L Wang, F Lu, Z Liu, C Yao, C Shen, X Pu, L Yu, X Fang, L Xu, J Mu, X Wu, R Zheng, N Wu, Q Zhao, Y Li, X Liu, M Wang, D Yu, D Hu, X Ji, D Guo, D Sun, Q Wang, Y Yang, F Liu, Q Mao, X Liang, J Ji, P Chen, X Mo, D Li, G Chai, Y Tang, X Li, Z Du, X Liu, C Dou, Z Yang, Q Meng, D Wang, R Wang, J Yang, H Schunkert, NJ Samani, S Kathiresan, MP Reilly, J Erdmann, X Peng, X Wu, D Liu, Y Yang, R Chen, B Qiang, D Gu
cell cycle and proliferation genes that are upregulated in the presence of LPS and differentially expressed in response to CBD + LPS. Mouse BV-2 microglial cells were pretreated with 10 uM CBD for 2 h, followed by addition of LPS for an additional 4 h. Gene expression was evaluated via microarray analysis. Data taken from Supplementary Table S2. Values presented are fold-change. Data available at GEO with accession number GSE70689.
Authors:
Ana Juknat, Maciej Pietr, Ewa Kozela, Neta Rimmerman, Rivka Levy, Fuying Gao, Giovanni Coppola, Daniel Geschwind, Zvi Vogel
cell cycle and proliferation genes that are upregulated in the presence of LPS and differentially expressed in response to THC + LPS. Mouse BV-2 microglial cells were pretreated with 10 uM THC for 2 h, followed by addition of LPS for an additional 4 h. Gene expression was evaluated via microarray analysis. Data taken from Supplementary Table S2. Values presented are fold-change. Data available at GEO with accession number GSE70689.
Authors:
Ana Juknat, Maciej Pietr, Ewa Kozela, Neta Rimmerman, Rivka Levy, Fuying Gao, Giovanni Coppola, Daniel Geschwind, Zvi Vogel
cell cycle and proliferation genes that are upregulated in the presence of LPS and differentially expressed in response to CBD. Mouse BV-2 microglial cells were pretreated with 10 uM CBD for 2 h. Gene expression was evaluated via microarray analysis. Data taken from Supplementary Table S2. Values presented are fold-change. Data available at GEO with accession number GSE70689.
Authors:
Ana Juknat, Maciej Pietr, Ewa Kozela, Neta Rimmerman, Rivka Levy, Fuying Gao, Giovanni Coppola, Daniel Geschwind, Zvi Vogel
cell cycle and proliferation genes that are upregulated in the presence of LPS and differentially expressed in response to THC. Mouse BV-2 microglial cells were pretreated with 10 uM THC for 2 h. Gene expression was evaluated via microarray analysis. Data taken from Supplementary Table S2. Values presented are fold-change. Data available at GEO with accession number GSE70689.
Authors:
Ana Juknat, Maciej Pietr, Ewa Kozela, Neta Rimmerman, Rivka Levy, Fuying Gao, Giovanni Coppola, Daniel Geschwind, Zvi Vogel
Genes that are upregulated in the presence of LPS and further enhanced in response to CBD. Mouse BV-2 microglial cells were pretreated with 10 uM CBD for 2 h, followed by LPS for an additional 4 h. Gene expression was evaluated via microarray analysis. Data taken from Table 2. Values presented are fold-change compared to untreated. Data available at GEO with accession number GSE70689.
Authors:
Ana Juknat, Maciej Pietr, Ewa Kozela, Neta Rimmerman, Rivka Levy, Fuying Gao, Giovanni Coppola, Daniel Geschwind, Zvi Vogel
Genes that are upregulated in the presence of LPS and further enhanced in response to THC. Mouse BV-2 microglial cells were pretreated with 10 uM THC for 2 h, followed by LPS for an additional 4 h. Gene expression was evaluated via microarray analysis. Data taken from Table 2. Values presented are fold-change compared to untreated. Data available at GEO with accession number GSE70689.
Authors:
Ana Juknat, Maciej Pietr, Ewa Kozela, Neta Rimmerman, Rivka Levy, Fuying Gao, Giovanni Coppola, Daniel Geschwind, Zvi Vogel
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