List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Parkinson's disease. The EFO term Parkinson's disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
CC Spencer, V Plagnol, A Strange, M Gardner, C Paisan-Ruiz, G Band, RA Barker, C Bellenguez, K Bhatia, H Blackburn, JM Blackwell, E Bramon, MA Brown, MA Brown, D Burn, JP Casas, PF Chinnery, CE Clarke, A Corvin, N Craddock, P Deloukas, S Edkins, J Evans, C Freeman, E Gray, J Hardy, G Hudson, S Hunt, J Jankowski, C Langford, AJ Lees, HS Markus, CG Mathew, MI McCarthy, KE Morrison, CN Palmer, JP Pearson, L Peltonen, M Pirinen, R Plomin, S Potter, A Rautanen, SJ Sawcer, Z Su, RC Trembath, AC Viswanathan, NW Williams, HR Morris, P Donnelly, NW Wood
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Parkinson's disease. The EFO term Parkinson's disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
TL Edwards, WK Scott, C Almonte, A Burt, EH Powell, GW Beecham, L Wang, S Züchner, I Konidari, G Wang, C Singer, F Nahab, B Scott, JM Stajich, M Pericak-Vance, J Haines, JM Vance, ER Martin
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Parkinson's disease. The EFO term Parkinson's disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
J Simón-Sánchez, C Schulte, JM Bras, M Sharma, JR Gibbs, D Berg, C Paisan-Ruiz, P Lichtner, SW Scholz, DG Hernandez, R Krüger, M Federoff, C Klein, A Goate, J Perlmutter, M Bonin, MA Nalls, T Illig, C Gieger, H Houlden, M Steffens, MS Okun, BA Racette, MR Cookson, KD Foote, HH Fernandez, BJ Traynor, S Schreiber, S Arepalli, R Zonozi, K Gwinn, M van der Brug, G Lopez, SJ Chanock, A Schatzkin, Y Park, A Hollenbeck, J Gao, X Huang, NW Wood, D Lorenz, G Deuschl, H Chen, O Riess, JA Hardy, AB Singleton, T Gasser
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Parkinson's disease. The EFO term Parkinson's disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
W Satake, Y Nakabayashi, I Mizuta, Y Hirota, C Ito, M Kubo, T Kawaguchi, T Tsunoda, M Watanabe, A Takeda, H Tomiyama, K Nakashima, K Hasegawa, F Obata, T Yoshikawa, H Kawakami, S Sakoda, M Yamamoto, N Hattori, M Murata, Y Nakamura, T Toda
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Parkinson's disease. The EFO term Parkinson's disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
CM Lill, JT Roehr, MB McQueen, FK Kavvoura, S Bagade, BM Schjeide, LM Schjeide, E Meissner, U Zauft, NC Allen, T Liu, M Schilling, KJ Anderson, G Beecham, D Berg, JM Biernacka, A Brice, AL DeStefano, CB Do, N Eriksson, SA Factor, MJ Farrer, T Foroud, T Gasser, T Hamza, JA Hardy, P Heutink, EM Hill-Burns, C Klein, JC Latourelle, DM Maraganore, ER Martin, M Martinez, RH Myers, MA Nalls, N Pankratz, H Payami, W Satake, WK Scott, M Sharma, AB Singleton, K Stefansson, T Toda, JY Tung, J Vance, NW Wood, CP Zabetian, P Young, RE Tanzi, MJ Khoury, F Zipp, H Lehrach, JP Ioannidis, L Bertram
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Parkinson's disease. The EFO term Parkinson's disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
MA Nalls, V Plagnol, DG Hernandez, M Sharma, UM Sheerin, M Saad, J Simón-Sánchez, C Schulte, S Lesage, S Sveinbjörnsdóttir, K Stefánsson, M Martinez, J Hardy, P Heutink, A Brice, T Gasser, AB Singleton, NW Wood
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Parkinson's disease. The EFO term Parkinson's disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
MA Nalls, N Pankratz, CM Lill, CB Do, DG Hernandez, M Saad, AL DeStefano, E Kara, J Bras, M Sharma, C Schulte, MF Keller, S Arepalli, C Letson, C Edsall, H Stefansson, X Liu, H Pliner, JH Lee, R Cheng, MA Ikram, JP Ioannidis, GM Hadjigeorgiou, JC Bis, M Martinez, JS Perlmutter, A Goate, K Marder, B Fiske, M Sutherland, G Xiromerisiou, RH Myers, LN Clark, K Stefansson, JA Hardy, P Heutink, H Chen, NW Wood, H Houlden, H Payami, A Brice, WK Scott, T Gasser, L Bertram, N Eriksson, T Foroud, AB Singleton
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Parkinson's disease. The EFO term Parkinson's disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
TH Hamza, CP Zabetian, A Tenesa, A Laederach, J Montimurro, D Yearout, DM Kay, KF Doheny, J Paschall, E Pugh, VI Kusel, R Collura, J Roberts, A Griffith, A Samii, WK Scott, J Nutt, SA Factor, H Payami
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Parkinson's disease. The EFO term Parkinson's disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
M Saad, S Lesage, A Saint-Pierre, JC Corvol, D Zelenika, JC Lambert, M Vidailhet, GD Mellick, E Lohmann, F Durif, P Pollak, P Damier, F Tison, PA Silburn, C Tzourio, S Forlani, MA Loriot, M Giroud, C Helmer, F Portet, P Amouyel, M Lathrop, A Elbaz, A Durr, M Martinez, A Brice
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Parkinson's disease. The EFO term Parkinson's disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
CB Do, JY Tung, E Dorfman, AK Kiefer, EM Drabant, U Francke, JL Mountain, SM Goldman, CM Tanner, JW Langston, A Wojcicki, N Eriksson
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Parkinson's disease (familial). The EFO term Parkinson's disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
N Pankratz, JB Wilk, JC Latourelle, AL DeStefano, C Halter, EW Pugh, KF Doheny, JF Gusella, WC Nichols, T Foroud, RH Myers
Data from GEO GSE194368 and analyzed using GEO2R, only top gene shown. Authors identified transcriptional adaptations of GR signaling in the amygdala of humans with OUD. Thus, GRs, their coregulators and downstream systems may represent viable therapeutic targets to treat the “stress side” of OUD.
Authors:
Stephanie A Carmack, Janaina C M Vendruscolo, M Adrienne McGinn, Jorge Miranda-Barrientos, Vez Repunte-Canonigo, Gabriel D Bosse, Daniele Mercatelli, Federico M Giorgi, Yu Fu, Anthony J Hinrich, Francine M Jodelka, Karen Ling, Robert O Messing, Randall T Peterson, Frank Rigo, Scott Edwards, Pietro P Sanna, Marisela Morales, Michelle L Hastings, George F Koob, Leandro F Vendruscolo
Using a two-stage process, several genes were initially identified using microarray analyses of cerebellar tissue from ethanol-treated PKCgamma mutant and wild-type mice. This geneset consists of genes related to PKCgamma wild-type expression changes due to chronic ethanol diet.
Authors:
Bowers BJ, Radcliffe RA, Smith AM, Miyamoto-Ditmon J, Wehner JM
To monitor the expression levels of a large number of genes and to identify genes not previously implicated in traumatic brain injury pathophysiology, a high-density oligonucleotide array containing 8,800 genes was interrogated. RNA samples were prepared from ipsilateral hippocampi 3 hr and 24 hr following lateral cortical impact injury and compared to samples from sham-operated controls.
Authors:
Matzilevich DA, Rall JM, Moore AN, Grill RJ, Dash PK
This gene set comprises 17 ethanol-dependence genes that were downregulated in the PKC-gamma mutant mice tested during the experiment. Background: Study shows that PKC-gamma wild-type mice develop tolerance to the sedative-hypnotic effects of ethanol after chronic ethanol treatment but mutant mice do not, making these genotypes a suitable model for identifying changes in gene expression related developing tolerance toward ethanol.
Authors:
Bowers BJ, Radcliffe RA, Smith AM, Miyamoto-Ditmon J, Wehner JM
This gene set contains 12 downregulated genes that were differentially expressed in five brain regions (amygdale, frontal cortex, striatum, nucleus acumbens, and hippocampus) in congenic mice strains in which inbred alcohol preferring (iP) chromosome 4 QTL interval was transferred to inbred non-alcohol preferring (iNP) mice strain (NP.P) mice. This study identified genes in the chromosome 4 QTL interval that affect alcoholic predisposition in these strain (NP.P) mice.
Striatum Gene Expression Correlates for C2HCOUNT30 measured in BXD RI Females obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The C2HCOUNT30 measures Open Field locomotion (activity beam breaks) 15-30 min post 2nd cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for C2HDIS30 measured in BXD RI Females obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The C2HDIS30 measures Open Field locomotion (cm) 15-30 min post 2nd cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for LM_PS_INTVL3 measured in BXD RI Females obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The LM_PS_INTVL3 measures Activity in 30 second interval post 3rd tone shock pairing under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for OF_DIST_10_15 measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The OF_DIST_10_15 measures Open Field - Total distance traveled 10-15 minutes under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
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