List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Coronary heart disease. The EFO term coronary heart disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JY Lee, BS Lee, DJ Shin, K Woo Park, YA Shin, K Joong Kim, L Heo, J Young Lee, Y Kyoung Kim, Y Jin Kim, C Bum Hong, SH Lee, D Yoon, H Jung Ku, IY Oh, BJ Kim, J Lee, SJ Park, J Kim, HK Kawk, JE Lee, HK Park, JE Lee, HY Nam, HY Park, C Shin, M Yokota, H Asano, M Nakatochi, T Matsubara, H Kitajima, K Yamamoto, HL Kim, BG Han, MC Cho, Y Jang, HS Kim, J Euy Park, JY Lee
To identify candidate genes influencing the active avoidance paradigm, authors utilized the bidirectionally selected Syracuse high- and low-avoidance (SHA and SLA) rat lines that markedly differ in their two-way active avoidance behavior. Rats were phenotyped, rested to allow recovery from testing stress and then hippocampi were dissected for gene expression profiling (Affymetrix U34A chips; approximately 7000 known genes), comparing SLA to SHA.
Authors:
Zhang S, Amstein T, Shen J, Brush FR, Gershenfeld HK
Molecular correlates of emotional learning using genetically selected rat lines. Syracuse high- and low-avoidance (SHA and SLA) rat lines that markedly differ in their two-way active avoidance behavior.
Authors:
Zhang S, Amstein T, Shen J, Brush FR, Gershenfeld HK
Molecular correlates of emotional learning using genetically selected rat lines. Syracuse high- and low-avoidance (SHA and SLA) rat lines that markedly differ in their two-way active avoidance behavior.
Authors:
Zhang S, Amstein T, Shen J, Brush FR, Gershenfeld HK
QTL associated with beta-carboline induced seizures 4. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (34527929)
Authors:
Gershenfeld HK, Neumann PE, Li X, St Jean PL, Paul SM
QTL associated with body weight at 8 weeks QTL 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (180303827)
QTL associated with body weight at 8 weeks QTL 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (136693037)
QTL associated with exploratory and excitability QTL 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (119449003)
Authors:
Zhang S, Lou Y, Amstein TM, Anyango M, Mohibullah N, Osoti A, Stancliffe D, King R, Iraqi F, Gershenfeld HK
QTL associated with exploratory and excitability QTL 4. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (39514309)
Authors:
Zhang S, Lou Y, Amstein TM, Anyango M, Mohibullah N, Osoti A, Stancliffe D, King R, Iraqi F, Gershenfeld HK
QTL associated with fluctuating asymmetry QTL 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (150044898)
Authors:
Zhang S, Lou Y, Amstein TM, Anyango M, Mohibullah N, Osoti A, Stancliffe D, King R, Iraqi F, Gershenfeld HK
QTL associated with fluctuating asymmetry QTL 10. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (20420342)
Authors:
Zhang S, Lou Y, Amstein TM, Anyango M, Mohibullah N, Osoti A, Stancliffe D, King R, Iraqi F, Gershenfeld HK
QTL associated with fluctuating asymmetry QTL 11. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (55517585)
Authors:
Zhang S, Lou Y, Amstein TM, Anyango M, Mohibullah N, Osoti A, Stancliffe D, King R, Iraqi F, Gershenfeld HK
QTL associated with fluctuating asymmetry QTL 5. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (27750456)
Authors:
Zhang S, Lou Y, Amstein TM, Anyango M, Mohibullah N, Osoti A, Stancliffe D, King R, Iraqi F, Gershenfeld HK
QTL associated with fluctuating asymmetry QTL 9. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (80110132)
Authors:
Zhang S, Lou Y, Amstein TM, Anyango M, Mohibullah N, Osoti A, Stancliffe D, King R, Iraqi F, Gershenfeld HK
QTL associated with segregation of mitochondrial DNA QTL 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (21199207)
Differentially expressed genes, with fold changes greater than 1.6, in common between both (A/J vs B6) AND (A/J vs C10 congenic lines) comparisons in P56 hippocampi contributing to anxiety-like behaviors.
Authors:
Kim S, Zhang S, Choi KH, Reister R, Do C, Baykiz AF, Gershenfeld HK
For genetic interventions, ELAV-GeneSwitch-dSir2EP2300 and ELAV-GeneSwitch-DN-Dmp53259H flies were aged for 10 or 40 Days as described for the life span experiments on food containing diluent or RU486. Total RNA was isolated from at least 75 females. Fold change in differential expression is uploaded.
The relationship between DR and resveratrol treatment was examined using RNA from only head/thorax females. Canton-S female flies from the same cohort were grown on high calorie food, low calorie food and high calorie food with resveratrol. GSEA analysis showed that of the 83 KEGG categories that were statistically significant in head/thorax DR, 81% (67 pathways) were shared with resveratrol. Heatmap fold change was uploaded.
Histone H4 acetylation (H4Ac) in response to ethanol was measure using the chromatin-immunoprecipitation assay (ChIP–chip) From Supplemental Data file 1, gene names and score were uploaded.
Authors:
Ghezzi A, Krishnan HR, Lew L, Prado FJ 3rd, Ong DS, Atkinson NS
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Waist-hip ratio. The EFO term waist-hip ratio was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
IM Heid, AU Jackson, JC Randall, TW Winkler, L Qi, V Steinthorsdottir, G Thorleifsson, MC Zillikens, EK Speliotes, R Mägi, T Workalemahu, CC White, N Bouatia-Naji, TB Harris, SI Berndt, E Ingelsson, CJ Willer, MN Weedon, J Luan, S Vedantam, T Esko, TO Kilpeläinen, Z Kutalik, S Li, KL Monda, AL Dixon, CC Holmes, LM Kaplan, L Liang, JL Min, MF Moffatt, C Molony, G Nicholson, EE Schadt, KT Zondervan, MF Feitosa, T Ferreira, H Lango Allen, RJ Weyant, E Wheeler, AR Wood, K Estrada, ME Goddard, G Lettre, M Mangino, DR Nyholt, S Purcell, AV Smith, PM Visscher, J Yang, SA McCarroll, J Nemesh, BF Voight, D Absher, N Amin, T Aspelund, L Coin, NL Glazer, C Hayward, NL Heard-Costa, JJ Hottenga, A Johansson, T Johnson, M Kaakinen, K Kapur, S Ketkar, JW Knowles, P Kraft, AT Kraja, C Lamina, MF Leitzmann, B McKnight, AP Morris, KK Ong, JR Perry, MJ Peters, O Polasek, I Prokopenko, NW Rayner, S Ripatti, F Rivadeneira, NR Robertson, S Sanna, U Sovio, I Surakka, A Teumer, S van Wingerden, V Vitart, JH Zhao, C Cavalcanti-Proença, PS Chines, E Fisher, JR Kulzer, C Lecoeur, N Narisu, C Sandholt, LJ Scott, K Silander, K Stark, ML Tammesoo, TM Teslovich, NJ Timpson, RM Watanabe, R Welch, DI Chasman, MN Cooper, JO Jansson, J Kettunen, RW Lawrence, N Pellikka, M Perola, L Vandenput, H Alavere, P Almgren, LD Atwood, AJ Bennett, R Biffar, LL Bonnycastle, SR Bornstein, TA Buchanan, H Campbell, IN Day, M Dei, M Dörr, P Elliott, MR Erdos, JG Eriksson, NB Freimer, M Fu, S Gaget, EJ Geus, AP Gjesing, H Grallert, J Grässler, CJ Groves, C Guiducci, AL Hartikainen, N Hassanali, AS Havulinna, KH Herzig, AA Hicks, J Hui, W Igl, P Jousilahti, A Jula, E Kajantie, L Kinnunen, I Kolcic, S Koskinen, P Kovacs, HK Kroemer, V Krzelj, J Kuusisto, K Kvaloy, J Laitinen, O Lantieri, GM Lathrop, ML Lokki, RN Luben, B Ludwig, WL McArdle, A McCarthy, MA Morken, M Nelis, MJ Neville, G Paré, AN Parker, JF Peden, I Pichler, KH Pietiläinen, CG Platou, A Pouta, M Ridderstråle, NJ Samani, J Saramies, J Sinisalo, JH Smit, RJ Strawbridge, HM Stringham, AJ Swift, M Teder-Laving, B Thomson, G Usala, JB van Meurs, GJ van Ommen, V Vatin, CB Volpato, H Wallaschofski, GB Walters, E Widen, SH Wild, G Willemsen, DR Witte, L Zgaga, P Zitting, JP Beilby, AL James, M Kähönen, T Lehtimäki, MS Nieminen, C Ohlsson, LJ Palmer, O Raitakari, PM Ridker, M Stumvoll, A Tönjes, J Viikari, B Balkau, Y Ben-Shlomo, RN Bergman, H Boeing, GD Smith, S Ebrahim, P Froguel, T Hansen, C Hengstenberg, K Hveem, B Isomaa, T Jørgensen, F Karpe, KT Khaw, M Laakso, DA Lawlor, M Marre, T Meitinger, A Metspalu, K Midthjell, O Pedersen, V Salomaa, PE Schwarz, T Tuomi, J Tuomilehto, TT Valle, NJ Wareham, AM Arnold, JS Beckmann, S Bergmann, E Boerwinkle, DI Boomsma, MJ Caulfield, FS Collins, G Eiriksdottir, V Gudnason, U Gyllensten, A Hamsten, AT Hattersley, A Hofman, FB Hu, T Illig, C Iribarren, MR Jarvelin, WH Kao, J Kaprio, LJ Launer, PB Munroe, B Oostra, BW Penninx, PP Pramstaller, BM Psaty, T Quertermous, A Rissanen, I Rudan, AR Shuldiner, N Soranzo, TD Spector, AC Syvanen, M Uda, A Uitterlinden, H Völzke, P Vollenweider, JF Wilson, JC Witteman, AF Wright, GR Abecasis, M Boehnke, IB Borecki, P Deloukas, TM Frayling, LC Groop, T Haritunians, DJ Hunter, RC Kaplan, KE North, JR O'Connell, L Peltonen, D Schlessinger, DP Strachan, JN Hirschhorn, TL Assimes, HE Wichmann, U Thorsteinsdottir, CM van Duijn, K Stefansson, LA Cupples, RJ Loos, I Barroso, MI McCarthy, CS Fox, KL Mohlke, CM Lindgren
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Coronary arterial lesions in patients with Kawasaki disease. The EFO term mucocutaneous lymph node syndrome was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JJ Kim, YM Park, D Yoon, KY Lee, M Seob Song, H Doo Lee, KJ Kim, IS Park, HK Nam, S Weon Yun, M Ki Han, Y Mi Hong, G Young Jang, JK Lee
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Helicobacter pylori serologic status. The EFO term anti-Heliobacter pylori serum IgG measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
J Mayerle, CM den Hoed, C Schurmann, L Stolk, G Homuth, MJ Peters, LG Capelle, K Zimmermann, F Rivadeneira, S Gruska, H Völzke, AC de Vries, U Völker, A Teumer, JB van Meurs, I Steinmetz, M Nauck, F Ernst, FU Weiss, A Hofman, M Zenker, HK Kroemer, H Prokisch, AG Uitterlinden, MM Lerch, EJ Kuipers, E Kuipers
GWAS: cardiovascular measurement, left ventricular hypertrophy
Description:
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Cardiac muscle measurement. The EFO term cardiovascular measurement, left ventricular hypertrophy was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
DK Arnett, KJ Meyers, RB Devereux, HK Tiwari, CC Gu, LK Vaughan, RT Perry, A Patki, SA Claas, YV Sun, U Broeckel, SL Kardia
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