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QTL associated with arthropathy in MRL and DBA/1 mice 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (57246565)
Authors:
Oishi H, Miyazaki T, Mizuki S, Kamogawa J, Lu LM, Tsubaki T, Arita N, Ono M, Yamamoto H, Nose M
QTL associated with circulating hormone level QTL 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (56600603)
Authors:
Harper JM, Galecki AT, Burke DT, Pinkosky SL, Miller RA
QTL associated with experimental allergic encephalomyelitis susceptibility 20. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (28475226)
QTL associated with insulin dependent diabetes susceptibility 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (60270627)
Authors:
Moritoki Y, Tsuda M, Tsuneyama K, Zhang W, Yoshida K, Lian ZX, Yang GX, Ridgway WM, Wicker LS, Ansari AA, Gershwin ME
QTL associated with inspiratory timing at baseline QTL 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (51563737)
Authors:
Tankersley CG, DiSilvestre DA, Jedlicka AE, Wilkins HM, Zhang L
QTL associated with novelty/stress induced locomotor activation 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (57246565)
QTL associated with phospholipid transfer protein activity QTL 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (69522098)
Authors:
Korstanje R, Albers JJ, Wolfbauer G, Li R, Tu AY, Churchill GA, Paigen BJ
QTL associated with radiation-induced apoptosis 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (76902079)
QTL associated with suppressor of superoxide production. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (66391506)
Authors:
Mathews CE, Dunn BD, Hannigan MO, Huang CK, Leiter EH
Gene expression correlates in the Hippocampus with HIC phenotypes.
GN11893 from
Philip VM, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
and NIAAA BXD Hippocampus CTL RNA-Seq (Oct20) TPM Log2 p<0.001
Differential gene expression in nucleus accumbens somatostatin interneurons_cocaine_mice_pvalue
Description:
To characterize transcriptional alterations that cocaine induces in these cells, we perform cell type-specific RNA-sequencing on FACS-isolated nuclei of somatostatin interneurons and identified 1100 DETs enriched for processes related to neural plasticity. To profile the entire (non poly-A selected) transcriptome of NAc somatostatin interneurons, we generated a transgenic reporter line (SST-TLG498 mice) to label the nuclei of these cells with a modified form of EGFP that is retained in the nuclear membrane (EGFP-F)22, enabling their isolation from NAc dissections using FACS. We succeeded in FACS-isolating nuclei suitable for RNA-sequencing from individual SST-TLG498 mice. We proceeded with differential expression analysis of the RNA-sequencing data to identify differentially expressed transcripts (DETs) in NAc somatostatin interneurons in response to repeated cocaine exposure: 778 transcripts were upregulated by cocaine and 322 were downregulated.
Authors:
Efrain A Ribeiro, Marine Salery, Joseph R Scarpa, Erin S Calipari, Peter J Hamilton, Stacy M Ku, Hope Kronman, Immanuel Purushothaman, Barbara Juarez, Mitra Heshmati, Marie Doyle, Casey Lardner, Dominicka Burek, Ana Strat, Stephen Pirpinias, Ezekiell Mouzon, Ming-Hu Han, Rachael L Neve, Rosemary C Bagot, Andrew Kasarskis, Ja Wook Koo, Eric J Nestler