List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Crohn's disease. The EFO term Crohn's disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
A Franke, DP McGovern, JC Barrett, K Wang, GL Radford-Smith, T Ahmad, CW Lees, T Balschun, J Lee, R Roberts, CA Anderson, JC Bis, S Bumpstead, D Ellinghaus, EM Festen, M Georges, T Green, T Haritunians, L Jostins, A Latiano, CG Mathew, GW Montgomery, NJ Prescott, S Raychaudhuri, JI Rotter, P Schumm, Y Sharma, LA Simms, KD Taylor, D Whiteman, C Wijmenga, RN Baldassano, M Barclay, TM Bayless, S Brand, C Büning, A Cohen, JF Colombel, M Cottone, L Stronati, T Denson, M De Vos, R D'Inca, M Dubinsky, C Edwards, T Florin, D Franchimont, R Gearry, J Glas, A Van Gossum, SL Guthery, J Halfvarson, HW Verspaget, JP Hugot, A Karban, D Laukens, I Lawrance, M Lemann, A Levine, C Libioulle, E Louis, C Mowat, W Newman, J Panés, A Phillips, DD Proctor, M Regueiro, R Russell, P Rutgeerts, J Sanderson, M Sans, F Seibold, AH Steinhart, PC Stokkers, L Torkvist, G Kullak-Ublick, D Wilson, T Walters, SR Targan, SR Brant, JD Rioux, M D'Amato, RK Weersma, S Kugathasan, AM Griffiths, JC Mansfield, S Vermeire, RH Duerr, MS Silverberg, J Satsangi, S Schreiber, JH Cho, V Annese, H Hakonarson, MJ Daly, M Parkes
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Pancreatic cancer. The EFO term pancreatic carcinoma was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
BM Wolpin, C Rizzato, P Kraft, C Kooperberg, GM Petersen, Z Wang, AA Arslan, L Beane-Freeman, PM Bracci, J Buring, F Canzian, EJ Duell, S Gallinger, GG Giles, GE Goodman, PJ Goodman, EJ Jacobs, A Kamineni, AP Klein, LN Kolonel, MH Kulke, D Li, N Malats, SH Olson, HA Risch, HD Sesso, K Visvanathan, E White, W Zheng, CC Abnet, D Albanes, G Andreotti, MA Austin, R Barfield, D Basso, SI Berndt, MC Boutron-Ruault, M Brotzman, MW Büchler, HB Bueno-de-Mesquita, P Bugert, L Burdette, D Campa, NE Caporaso, G Capurso, C Chung, M Cotterchio, E Costello, J Elena, N Funel, JM Gaziano, NA Giese, EL Giovannucci, M Goggins, MJ Gorman, M Gross, CA Haiman, M Hassan, KJ Helzlsouer, BE Henderson, EA Holly, N Hu, DJ Hunter, F Innocenti, M Jenab, R Kaaks, TJ Key, KT Khaw, EA Klein, M Kogevinas, V Krogh, J Kupcinskas, RC Kurtz, A LaCroix, MT Landi, S Landi, L Le Marchand, A Mambrini, S Mannisto, RL Milne, Y Nakamura, AL Oberg, K Owzar, AV Patel, PH Peeters, U Peters, R Pezzilli, A Piepoli, M Porta, FX Real, E Riboli, N Rothman, A Scarpa, XO Shu, DT Silverman, P Soucek, M Sund, R Talar-Wojnarowska, PR Taylor, GE Theodoropoulos, M Thornquist, A Tjønneland, GS Tobias, D Trichopoulos, P Vodicka, J Wactawski-Wende, N Wentzensen, C Wu, H Yu, K Yu, A Zeleniuch-Jacquotte, R Hoover, P Hartge, C Fuchs, SJ Chanock, RS Stolzenberg-Solomon, LT Amundadottir
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Celiac disease or Rheumatoid arthritis. The EFO term immune system disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
A Zhernakova, EA Stahl, G Trynka, S Raychaudhuri, EA Festen, L Franke, HJ Westra, RS Fehrmann, FA Kurreeman, B Thomson, N Gupta, J Romanos, R McManus, AW Ryan, G Turner, E Brouwer, MD Posthumus, EF Remmers, F Tucci, R Toes, E Grandone, MC Mazzilli, A Rybak, B Cukrowska, MJ Coenen, TR Radstake, PL van Riel, Y Li, PI de Bakker, PK Gregersen, J Worthington, KA Siminovitch, L Klareskog, TW Huizinga, C Wijmenga, RM Plenge
GWAS: forced expiratory volume, response to bronchodilator
Description:
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Post bronchodilator FEV1. The EFO term forced expiratory volume, response to bronchodilator was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
SM Lutz, MH Cho, K Young, CP Hersh, PJ Castaldi, ML McDonald, E Regan, M Mattheisen, DL DeMeo, M Parker, M Foreman, BJ Make, RL Jensen, R Casaburi, DA Lomas, SP Bhatt, P Bakke, A Gulsvik, JD Crapo, TH Beaty, NM Laird, C Lange, JE Hokanson, EK Silverman
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Endometrial cancer. The EFO term endometrial carcinoma was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
TH Cheng, DJ Thompson, TA O'Mara, JN Painter, DM Glubb, S Flach, A Lewis, JD French, L Freeman-Mills, D Church, M Gorman, L Martin, S Hodgson, PM Webb, J Attia, EG Holliday, M McEvoy, RJ Scott, AK Henders, NG Martin, GW Montgomery, DR Nyholt, S Ahmed, CS Healey, M Shah, J Dennis, PA Fasching, MW Beckmann, A Hein, AB Ekici, P Hall, K Czene, H Darabi, J Li, T Dörk, M Dürst, P Hillemanns, I Runnebaum, F Amant, S Schrauwen, H Zhao, D Lambrechts, J Depreeuw, SC Dowdy, EL Goode, BL Fridley, SJ Winham, TS Njølstad, HB Salvesen, J Trovik, HM Werner, K Ashton, G Otton, T Proietto, T Liu, M Mints, E Tham, MJ Li, SH Yip, J Wang, MK Bolla, K Michailidou, Q Wang, JP Tyrer, M Dunlop, R Houlston, C Palles, JL Hopper, J Peto, AJ Swerdlow, B Burwinkel, H Brenner, A Meindl, H Brauch, A Lindblom, J Chang-Claude, FJ Couch, GG Giles, VN Kristensen, A Cox, JM Cunningham, PD Pharoah, AM Dunning, SL Edwards, DF Easton, I Tomlinson, AB Spurdle
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Endometrial endometrioid carcinoma. The EFO term endometrial endometrioid carcinoma was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
TH Cheng, DJ Thompson, TA O'Mara, JN Painter, DM Glubb, S Flach, A Lewis, JD French, L Freeman-Mills, D Church, M Gorman, L Martin, S Hodgson, PM Webb, J Attia, EG Holliday, M McEvoy, RJ Scott, AK Henders, NG Martin, GW Montgomery, DR Nyholt, S Ahmed, CS Healey, M Shah, J Dennis, PA Fasching, MW Beckmann, A Hein, AB Ekici, P Hall, K Czene, H Darabi, J Li, T Dörk, M Dürst, P Hillemanns, I Runnebaum, F Amant, S Schrauwen, H Zhao, D Lambrechts, J Depreeuw, SC Dowdy, EL Goode, BL Fridley, SJ Winham, TS Njølstad, HB Salvesen, J Trovik, HM Werner, K Ashton, G Otton, T Proietto, T Liu, M Mints, E Tham, MJ Li, SH Yip, J Wang, MK Bolla, K Michailidou, Q Wang, JP Tyrer, M Dunlop, R Houlston, C Palles, JL Hopper, J Peto, AJ Swerdlow, B Burwinkel, H Brenner, A Meindl, H Brauch, A Lindblom, J Chang-Claude, FJ Couch, GG Giles, VN Kristensen, A Cox, JM Cunningham, PD Pharoah, AM Dunning, SL Edwards, DF Easton, I Tomlinson, AB Spurdle
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Orofacial clefts. The EFO term progranulin measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
KU Ludwig, E Mangold, S Herms, S Nowak, H Reutter, A Paul, J Becker, R Herberz, T AlChawa, E Nasser, AC Böhmer, M Mattheisen, MA Alblas, S Barth, N Kluck, C Lauster, B Braumann, RH Reich, A Hemprich, S Pötzsch, B Blaumeiser, N Daratsianos, T Kreusch, JC Murray, ML Marazita, I Ruczinski, AF Scott, TH Beaty, FJ Kramer, TF Wienker, RP Steegers-Theunissen, M Rubini, PA Mossey, P Hoffmann, C Lange, S Cichon, P Propping, M Knapp, MM Nöthen
GWAS: response to methotrexate, chronic childhood arthritis
Description:
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Response to methotrexate in juvenile idiopathic arthritis. The EFO term response to methotrexate, chronic childhood arthritis was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
J Cobb, E Cule, H Moncrieffe, A Hinks, S Ursu, F Patrick, L Kassoumeri, E Flynn, M Bulatović, N Wulffraat, B van Zelst, R de Jonge, M Bohm, P Dolezalova, S Hirani, S Newman, P Whitworth, TR Southwood, M De Iorio, LR Wedderburn, W Thomson
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Ovarian cancer. The EFO term ovarian carcinoma was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
EL Goode, G Chenevix-Trench, H Song, SJ Ramus, M Notaridou, K Lawrenson, M Widschwendter, RA Vierkant, MC Larson, SK Kjaer, MJ Birrer, A Berchuck, J Schildkraut, I Tomlinson, LA Kiemeney, LS Cook, J Gronwald, M Garcia-Closas, ME Gore, I Campbell, AS Whittemore, R Sutphen, C Phelan, H Anton-Culver, CL Pearce, D Lambrechts, MA Rossing, J Chang-Claude, KB Moysich, MT Goodman, T Dörk, H Nevanlinna, RB Ness, T Rafnar, C Hogdall, E Hogdall, BL Fridley, JM Cunningham, W Sieh, V McGuire, AK Godwin, DW Cramer, D Hernandez, D Levine, K Lu, ES Iversen, RT Palmieri, R Houlston, AM van Altena, KK Aben, LF Massuger, A Brooks-Wilson, LE Kelemen, ND Le, A Jakubowska, J Lubinski, K Medrek, A Stafford, DF Easton, J Tyrer, KL Bolton, P Harrington, D Eccles, A Chen, AN Molina, BN Davila, H Arango, YY Tsai, Z Chen, HA Risch, J McLaughlin, SA Narod, A Ziogas, W Brewster, A Gentry-Maharaj, U Menon, AH Wu, DO Stram, MC Pike, J Beesley, PM Webb, X Chen, AB Ekici, FC Thiel, MW Beckmann, H Yang, N Wentzensen, J Lissowska, PA Fasching, E Despierre, F Amant, I Vergote, J Doherty, R Hein, S Wang-Gohrke, G Lurie, ME Carney, PJ Thompson, I Runnebaum, P Hillemanns, M Dürst, N Antonenkova, N Bogdanova, A Leminen, R Butzow, T Heikkinen, K Stefansson, P Sulem, S Besenbacher, TA Sellers, SA Gayther, PD Pharoah
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Crohn's disease. The EFO term Crohn's disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
L Jostins, S Ripke, RK Weersma, RH Duerr, DP McGovern, KY Hui, JC Lee, LP Schumm, Y Sharma, CA Anderson, J Essers, M Mitrovic, K Ning, I Cleynen, E Theatre, SL Spain, S Raychaudhuri, P Goyette, Z Wei, C Abraham, JP Achkar, T Ahmad, L Amininejad, AN Ananthakrishnan, V Andersen, JM Andrews, L Baidoo, T Balschun, PA Bampton, A Bitton, G Boucher, S Brand, C Büning, A Cohain, S Cichon, M D'Amato, D De Jong, KL Devaney, M Dubinsky, C Edwards, D Ellinghaus, LR Ferguson, D Franchimont, K Fransen, R Gearry, M Georges, C Gieger, J Glas, T Haritunians, A Hart, C Hawkey, M Hedl, X Hu, TH Karlsen, L Kupcinskas, S Kugathasan, A Latiano, D Laukens, IC Lawrance, CW Lees, E Louis, G Mahy, J Mansfield, AR Morgan, C Mowat, W Newman, O Palmieri, CY Ponsioen, U Potocnik, NJ Prescott, M Regueiro, JI Rotter, RK Russell, JD Sanderson, M Sans, J Satsangi, S Schreiber, LA Simms, J Sventoraityte, SR Targan, KD Taylor, M Tremelling, HW Verspaget, M De Vos, C Wijmenga, DC Wilson, J Winkelmann, RJ Xavier, S Zeissig, B Zhang, CK Zhang, H Zhao, MS Silverberg, V Annese, H Hakonarson, SR Brant, G Radford-Smith, CG Mathew, JD Rioux, EE Schadt, MJ Daly, A Franke, M Parkes, S Vermeire, JC Barrett, JH Cho
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Cleft lip. The EFO term cleft lip was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
TH Beaty, JC Murray, ML Marazita, RG Munger, I Ruczinski, JB Hetmanski, KY Liang, T Wu, T Murray, MD Fallin, RA Redett, G Raymond, H Schwender, SC Jin, ME Cooper, M Dunnwald, MA Mansilla, E Leslie, S Bullard, AC Lidral, LM Moreno, R Menezes, AR Vieira, A Petrin, AJ Wilcox, RT Lie, EW Jabs, YH Wu-Chou, PK Chen, H Wang, X Ye, S Huang, V Yeow, SS Chong, SH Jee, B Shi, K Christensen, M Melbye, KF Doheny, EW Pugh, H Ling, EE Castilla, AE Czeizel, L Ma, LL Field, L Brody, F Pangilinan, JL Mills, AM Molloy, PN Kirke, JM Scott, JM Scott, M Arcos-Burgos, AF Scott
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Atopic dermatitis. The EFO term atopic eczema was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
T Hirota, A Takahashi, M Kubo, T Tsunoda, K Tomita, M Sakashita, T Yamada, S Fujieda, S Tanaka, S Doi, A Miyatake, T Enomoto, C Nishiyama, N Nakano, K Maeda, K Okumura, H Ogawa, S Ikeda, E Noguchi, T Sakamoto, N Hizawa, K Ebe, H Saeki, T Sasaki, T Ebihara, M Amagai, S Takeuchi, M Furue, Y Nakamura, M Tamari
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Type 2 diabetes. The EFO term type II diabetes mellitus was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
A Mahajan, MJ Go, W Zhang, JE Below, KJ Gaulton, T Ferreira, M Horikoshi, AD Johnson, MC Ng, I Prokopenko, D Saleheen, X Wang, E Zeggini, GR Abecasis, LS Adair, P Almgren, M Atalay, T Aung, D Baldassarre, B Balkau, Y Bao, AH Barnett, I Barroso, A Basit, LF Been, J Beilby, GI Bell, R Benediktsson, RN Bergman, BO Boehm, E Boerwinkle, LL Bonnycastle, N Burtt, Q Cai, H Campbell, J Carey, S Cauchi, M Caulfield, JC Chan, LC Chang, TJ Chang, YC Chang, G Charpentier, CH Chen, H Chen, YT Chen, KS Chia, M Chidambaram, PS Chines, NH Cho, YM Cho, LM Chuang, FS Collins, MC Cornelis, DJ Couper, AT Crenshaw, RM van Dam, J Danesh, D Das, U de Faire, G Dedoussis, P Deloukas, AS Dimas, C Dina, AS Doney, PJ Donnelly, M Dorkhan, C van Duijn, J Dupuis, S Edkins, P Elliott, V Emilsson, R Erbel, JG Eriksson, J Escobedo, T Esko, E Eury, JC Florez, P Fontanillas, NG Forouhi, T Forsen, C Fox, RM Fraser, TM Frayling, P Froguel, P Frossard, Y Gao, K Gertow, C Gieger, B Gigante, H Grallert, GB Grant, LC Grrop, CJ Groves, E Grundberg, C Guiducci, A Hamsten, BG Han, K Hara, N Hassanali, AT Hattersley, C Hayward, AK Hedman, C Herder, A Hofman, OL Holmen, K Hovingh, AB Hreidarsson, C Hu, FB Hu, J Hui, SE Humphries, SE Hunt, DJ Hunter, K Hveem, ZI Hydrie, H Ikegami, T Illig, E Ingelsson, M Islam, B Isomaa, AU Jackson, T Jafar, A James, W Jia, KH Jöckel, A Jonsson, JB Jowett, T Kadowaki, HM Kang, S Kanoni, WH Kao, S Kathiresan, N Kato, P Katulanda, KM Keinanen-Kiukaanniemi, AM Kelly, H Khan, KT Khaw, CC Khor, HL Kim, S Kim, YJ Kim, L Kinnunen, N Klopp, A Kong, E Korpi-Hyövälti, S Kowlessur, P Kraft, J Kravic, MM Kristensen, S Krithika, A Kumar, J Kumate, J Kuusisto, SH Kwak, M Laakso, V Lagou, TA Lakka, C Langenberg, C Langford, R Lawrence, K Leander, JM Lee, NR Lee, M Li, X Li, Y Li, J Liang, S Liju, WY Lim, L Lind, CM Lindgren, E Lindholm, CT Liu, JJ Liu, S Lobbens, J Long, RJ Loos, W Lu, J Luan, V Lyssenko, RC Ma, S Maeda, R Mägi, S Männisto, DR Matthews, JB Meigs, O Melander, A Metspalu, J Meyer, G Mirza, E Mihailov, S Moebus, V Mohan, KL Mohlke, AD Morris, TW Mühleisen, M Müller-Nurasyid, B Musk, J Nakamura, E Nakashima, P Navarro, PK Ng, AC Nica, PM Nilsson, I Njølstad, MM Nöthen, K Ohnaka, TH Ong, KR Owen, CN Palmer, JS Pankow, KS Park, M Parkin, S Pechlivanis, NL Pedersen, L Peltonen, JR Perry, A Peters, JM Pinidiyapathirage, CG Platou, S Potter, JF Price, L Qi, V Radha, L Rallidis, A Rasheed, W Rathman, R Rauramaa, S Raychaudhuri, NW Rayner, SD Rees, E Rehnberg, S Ripatti, N Robertson, M Roden, EJ Rossin, I Rudan, D Rybin, TE Saaristo, V Salomaa, J Saltevo, M Samuel, DK Sanghera, J Saramies, J Scott, LJ Scott, RA Scott, AV Segrè, J Sehmi, B Sennblad, N Shah, S Shah, AS Shera, XO Shu, AR Shuldiner, G Sigurđsson, E Sijbrands, A Silveira, X Sim, S Sivapalaratnam, KS Small, WY So, A Stančáková, K Stefansson, G Steinbach, V Steinthorsdottir, K Stirrups, RJ Strawbridge, HM Stringham, Q Sun, C Suo, AC Syvänen, R Takayanagi, F Takeuchi, WT Tay, TM Teslovich, B Thorand, G Thorleifsson, U Thorsteinsdottir, E Tikkanen, J Trakalo, E Tremoli, MD Trip, FJ Tsai, T Tuomi, J Tuomilehto, AG Uitterlinden, A Valladares-Salgado, S Vedantam, F Veglia, BF Voight, C Wang, NJ Wareham, R Wennauer, AR Wickremasinghe, T Wilsgaard, JF Wilson, S Wiltshire, W Winckler, TY Wong, AR Wood, JY Wu, Y Wu, K Yamamoto, T Yamauchi, M Yang, L Yengo, M Yokota, R Young, D Zabaneh, F Zhang, R Zhang, W Zheng, PZ Zimmet, D Altshuler, DW Bowden, YS Cho, NJ Cox, M Cruz, CL Hanis, J Kooner, JY Lee, M Seielstad, YY Teo, M Boehnke, EJ Parra, JC Chambers, ES Tai, MI McCarthy, AP Morris
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Rheumatoid arthritis. The EFO term rheumatoid arthritis was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
Y Okada, D Wu, G Trynka, T Raj, C Terao, K Ikari, Y Kochi, K Ohmura, A Suzuki, S Yoshida, RR Graham, A Manoharan, W Ortmann, T Bhangale, JC Denny, RJ Carroll, AE Eyler, JD Greenberg, JM Kremer, DA Pappas, L Jiang, J Yin, L Ye, DF Su, J Yang, G Xie, E Keystone, HJ Westra, T Esko, A Metspalu, X Zhou, N Gupta, D Mirel, EA Stahl, D Diogo, J Cui, K Liao, MH Guo, K Myouzen, T Kawaguchi, MJ Coenen, PL van Riel, MA van de Laar, HJ Guchelaar, TW Huizinga, P Dieudé, X Mariette, SL Bridges, A Zhernakova, RE Toes, PP Tak, C Miceli-Richard, SY Bang, HS Lee, J Martin, MA Gonzalez-Gay, L Rodriguez-Rodriguez, S Rantapää-Dahlqvist, L Arlestig, HK Choi, Y Kamatani, P Galan, M Lathrop, S Eyre, J Bowes, A Barton, N de Vries, LW Moreland, LA Criswell, EW Karlson, A Taniguchi, R Yamada, M Kubo, JS Liu, SC Bae, J Worthington, L Padyukov, L Klareskog, PK Gregersen, S Raychaudhuri, BE Stranger, PL De Jager, L Franke, PM Visscher, MA Brown, H Yamanaka, T Mimori, A Takahashi, H Xu, TW Behrens, KA Siminovitch, S Momohara, F Matsuda, K Yamamoto, RM Plenge
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Immunoglobulin A. The EFO term protein measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
RC Ferreira, Q Pan-Hammarström, RR Graham, V Gateva, G Fontán, AT Lee, W Ortmann, E Urcelay, M Fernández-Arquero, C Núñez, G Jorgensen, BR Ludviksson, S Koskinen, K Haimila, HF Clark, L Klareskog, PK Gregersen, TW Behrens, L Hammarström
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Inflammatory bowel disease. The EFO term inflammatory bowel disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JZ Liu, S van Sommeren, H Huang, SC Ng, R Alberts, A Takahashi, S Ripke, JC Lee, L Jostins, T Shah, S Abedian, JH Cheon, J Cho, NE Daryani, L Franke, Y Fuyuno, A Hart, RC Juyal, G Juyal, WH Kim, AP Morris, H Poustchi, WG Newman, V Midha, TR Orchard, H Vahedi, A Sood, JJ Sung, R Malekzadeh, HJ Westra, K Yamazaki, SK Yang, JC Barrett, A Franke, BZ Alizadeh, M Parkes, T B K, MJ Daly, M Kubo, CA Anderson, RK Weersma
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Crohn's disease. The EFO term Crohn's disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JZ Liu, S van Sommeren, H Huang, SC Ng, R Alberts, A Takahashi, S Ripke, JC Lee, L Jostins, T Shah, S Abedian, JH Cheon, J Cho, NE Daryani, L Franke, Y Fuyuno, A Hart, RC Juyal, G Juyal, WH Kim, AP Morris, H Poustchi, WG Newman, V Midha, TR Orchard, H Vahedi, A Sood, JJ Sung, R Malekzadeh, HJ Westra, K Yamazaki, SK Yang, JC Barrett, A Franke, BZ Alizadeh, M Parkes, T B K, MJ Daly, M Kubo, CA Anderson, RK Weersma
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Epithelial ovarian cancer. The EFO term Malignant epithelial tumor of ovary was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
KB Kuchenbaecker, SJ Ramus, J Tyrer, A Lee, HC Shen, J Beesley, K Lawrenson, L McGuffog, S Healey, JM Lee, TJ Spindler, YG Lin, T Pejovic, Y Bean, Q Li, S Coetzee, D Hazelett, A Miron, M Southey, MB Terry, DE Goldgar, SS Buys, R Janavicius, CM Dorfling, EJ van Rensburg, SL Neuhausen, YC Ding, TV Hansen, L Jønson, AM Gerdes, B Ejlertsen, D Barrowdale, J Dennis, J Benitez, A Osorio, MJ Garcia, I Komenaka, JN Weitzel, P Ganschow, P Peterlongo, L Bernard, A Viel, B Bonanni, B Peissel, S Manoukian, P Radice, L Papi, L Ottini, F Fostira, I Konstantopoulou, J Garber, D Frost, J Perkins, R Platte, S Ellis, AK Godwin, RK Schmutzler, A Meindl, C Engel, C Sutter, OM Sinilnikova, F Damiola, S Mazoyer, D Stoppa-Lyonnet, K Claes, K De Leeneer, J Kirk, GC Rodriguez, M Piedmonte, DM O'Malley, M de la Hoya, T Caldes, K Aittomäki, H Nevanlinna, JM Collée, MA Rookus, JC Oosterwijk, L Tihomirova, N Tung, U Hamann, C Isaccs, M Tischkowitz, EN Imyanitov, MA Caligo, IG Campbell, FB Hogervorst, E Olah, O Diez, I Blanco, J Brunet, C Lazaro, MA Pujana, A Jakubowska, J Gronwald, J Lubinski, G Sukiennicki, RB Barkardottir, M Plante, J Simard, P Soucy, M Montagna, S Tognazzo, MR Teixeira, VS Pankratz, X Wang, N Lindor, CI Szabo, N Kauff, J Vijai, CA Aghajanian, G Pfeiler, A Berger, CF Singer, MK Tea, CM Phelan, MH Greene, PL Mai, G Rennert, AM Mulligan, S Tchatchou, IL Andrulis, G Glendon, AE Toland, UB Jensen, TA Kruse, M Thomassen, A Bojesen, J Zidan, E Friedman, Y Laitman, M Soller, A Liljegren, B Arver, Z Einbeigi, M Stenmark-Askmalm, OI Olopade, RL Nussbaum, TR Rebbeck, KL Nathanson, SM Domchek, KH Lu, BY Karlan, C Walsh, J Lester, A Hein, AB Ekici, MW Beckmann, PA Fasching, D Lambrechts, E Van Nieuwenhuysen, I Vergote, S Lambrechts, E Dicks, JA Doherty, KG Wicklund, MA Rossing, A Rudolph, J Chang-Claude, S Wang-Gohrke, U Eilber, KB Moysich, K Odunsi, L Sucheston, S Lele, LR Wilkens, MT Goodman, PJ Thompson, YB Shvetsov, IB Runnebaum, M Dürst, P Hillemanns, T Dörk, N Antonenkova, N Bogdanova, A Leminen, LM Pelttari, R Butzow, F Modugno, JL Kelley, RP Edwards, RB Ness, A du Bois, F Heitz, I Schwaab, P Harter, K Matsuo, S Hosono, S Orsulic, A Jensen, SK Kjaer, E Hogdall, HN Hasmad, MA Azmi, SH Teo, YL Woo, BL Fridley, EL Goode, JM Cunningham, RA Vierkant, F Bruinsma, GG Giles, D Liang, MA Hildebrandt, X Wu, DA Levine, M Bisogna, A Berchuck, ES Iversen, JM Schildkraut, P Concannon, RP Weber, DW Cramer, KL Terry, EM Poole, SS Tworoger, EV Bandera, I Orlow, SH Olson, C Krakstad, HB Salvesen, IL Tangen, L Bjorge, AM van Altena, KK Aben, LA Kiemeney, LF Massuger, M Kellar, A Brooks-Wilson, LE Kelemen, LS Cook, ND Le, C Cybulski, H Yang, J Lissowska, LA Brinton, N Wentzensen, C Hogdall, L Lundvall, L Nedergaard, H Baker, H Song, D Eccles, I McNeish, J Paul, K Carty, N Siddiqui, R Glasspool, AS Whittemore, JH Rothstein, V McGuire, W Sieh, BT Ji, W Zheng, XO Shu, YT Gao, B Rosen, HA Risch, JR McLaughlin, SA Narod, AN Monteiro, A Chen, HY Lin, J Permuth-Wey, TA Sellers, YY Tsai, Z Chen, A Ziogas, H Anton-Culver, A Gentry-Maharaj, U Menon, P Harrington, AW Lee, AH Wu, CL Pearce, G Coetzee, MC Pike, A Dansonka-Mieszkowska, A Timorek, IK Rzepecka, J Kupryjanczyk, M Freedman, H Noushmehr, DF Easton, K Offit, FJ Couch, S Gayther, PP Pharoah, AC Antoniou, G Chenevix-Trench
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Orofacial clefts. The EFO term cleft lip was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
SF Grant, K Wang, H Zhang, W Glaberson, K Annaiah, CE Kim, JP Bradfield, JT Glessner, KA Thomas, M Garris, EC Frackelton, FG Otieno, RM Chiavacci, HD Nah, RE Kirschner, H Hakonarson
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Orofacial clefts. The EFO term cleft lip was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
S Birnbaum, KU Ludwig, H Reutter, S Herms, M Steffens, M Rubini, C Baluardo, M Ferrian, N Almeida de Assis, MA Alblas, S Barth, J Freudenberg, C Lauster, G Schmidt, M Scheer, B Braumann, SJ Bergé, RH Reich, F Schiefke, A Hemprich, S Pötzsch, RP Steegers-Theunissen, B Pötzsch, S Moebus, B Horsthemke, FJ Kramer, TF Wienker, PA Mossey, P Propping, S Cichon, P Hoffmann, M Knapp, MM Nöthen, E Mangold
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Metabolite levels (Dihydroxy docosatrienoic acid). The EFO term dihydroxy docosatrienoic acid measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
B Yu, Y Zheng, D Alexander, TA Manolio, A Alonso, JA Nettleton, E Boerwinkle
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Celiac disease. The EFO term celiac disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
PC Dubois, G Trynka, L Franke, KA Hunt, J Romanos, A Curtotti, A Zhernakova, GA Heap, R Adány, A Aromaa, MT Bardella, LH van den Berg, NA Bockett, EG de la Concha, B Dema, RS Fehrmann, M Fernández-Arquero, S Fiatal, E Grandone, PM Green, HJ Groen, R Gwilliam, RH Houwen, SE Hunt, K Kaukinen, D Kelleher, I Korponay-Szabo, K Kurppa, P MacMathuna, M Mäki, MC Mazzilli, OT McCann, ML Mearin, CA Mein, MM Mirza, V Mistry, B Mora, KI Morley, CJ Mulder, JA Murray, C Núñez, E Oosterom, RA Ophoff, I Polanco, L Peltonen, M Platteel, A Rybak, V Salomaa, JJ Schweizer, MP Sperandeo, GJ Tack, G Turner, JH Veldink, WH Verbeek, RK Weersma, VM Wolters, E Urcelay, B Cukrowska, L Greco, SL Neuhausen, R McManus, D Barisani, P Deloukas, JC Barrett, P Saavalainen, C Wijmenga, DA van Heel
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Ovarian cancer. The EFO term ovarian carcinoma was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
PD Pharoah, YY Tsai, SJ Ramus, CM Phelan, EL Goode, K Lawrenson, M Buckley, BL Fridley, JP Tyrer, H Shen, R Weber, R Karevan, MC Larson, H Song, DC Tessier, F Bacot, D Vincent, JM Cunningham, J Dennis, E Dicks, KK Aben, H Anton-Culver, N Antonenkova, SM Armasu, L Baglietto, EV Bandera, MW Beckmann, MJ Birrer, G Bloom, N Bogdanova, JD Brenton, LA Brinton, A Brooks-Wilson, R Brown, R Butzow, I Campbell, ME Carney, RS Carvalho, J Chang-Claude, YA Chen, Z Chen, WH Chow, MS Cicek, G Coetzee, LS Cook, DW Cramer, C Cybulski, A Dansonka-Mieszkowska, E Despierre, JA Doherty, T Dörk, A du Bois, M Dürst, D Eccles, R Edwards, AB Ekici, PA Fasching, D Fenstermacher, J Flanagan, YT Gao, M Garcia-Closas, A Gentry-Maharaj, G Giles, A Gjyshi, M Gore, J Gronwald, Q Guo, MK Halle, P Harter, A Hein, F Heitz, P Hillemanns, M Hoatlin, E Høgdall, CK Høgdall, S Hosono, A Jakubowska, A Jensen, KR Kalli, BY Karlan, LE Kelemen, LA Kiemeney, SK Kjaer, GE Konecny, C Krakstad, J Kupryjanczyk, D Lambrechts, S Lambrechts, ND Le, N Lee, J Lee, A Leminen, BK Lim, J Lissowska, J Lubiński, L Lundvall, G Lurie, LF Massuger, K Matsuo, V McGuire, JR McLaughlin, U Menon, F Modugno, KB Moysich, T Nakanishi, SA Narod, RB Ness, H Nevanlinna, S Nickels, H Noushmehr, K Odunsi, S Olson, I Orlow, J Paul, T Pejovic, LM Pelttari, J Permuth-Wey, MC Pike, EM Poole, X Qu, HA Risch, L Rodriguez-Rodriguez, MA Rossing, A Rudolph, I Runnebaum, IK Rzepecka, HB Salvesen, I Schwaab, G Severi, H Shen, V Shridhar, XO Shu, W Sieh, MC Southey, P Spellman, K Tajima, SH Teo, KL Terry, PJ Thompson, A Timorek, SS Tworoger, AM van Altena, D van den Berg, I Vergote, RA Vierkant, AF Vitonis, S Wang-Gohrke, N Wentzensen, AS Whittemore, E Wik, B Winterhoff, YL Woo, AH Wu, HP Yang, W Zheng, A Ziogas, F Zulkifli, MT Goodman, P Hall, DF Easton, CL Pearce, A Berchuck, G Chenevix-Trench, E Iversen, AN Monteiro, SA Gayther, JM Schildkraut, TA Sellers
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Diffuse large B cell lymphoma. The EFO term diffuse large B-cell lymphoma was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JR Cerhan, SI Berndt, J Vijai, H Ghesquières, J McKay, SS Wang, Z Wang, M Yeager, L Conde, PI de Bakker, A Nieters, D Cox, L Burdett, A Monnereau, CR Flowers, AJ De Roos, AR Brooks-Wilson, Q Lan, G Severi, M Melbye, J Gu, RD Jackson, E Kane, LR Teras, MP Purdue, CM Vajdic, JJ Spinelli, GG Giles, D Albanes, RS Kelly, M Zucca, KA Bertrand, A Zeleniuch-Jacquotte, C Lawrence, A Hutchinson, D Zhi, TM Habermann, BK Link, AJ Novak, A Dogan, YW Asmann, M Liebow, CA Thompson, SM Ansell, TE Witzig, GJ Weiner, AS Veron, D Zelenika, H Tilly, C Haioun, TJ Molina, H Hjalgrim, B Glimelius, HO Adami, PM Bracci, J Riby, MT Smith, EA Holly, W Cozen, P Hartge, LM Morton, RK Severson, LF Tinker, KE North, N Becker, Y Benavente, P Boffetta, P Brennan, L Foretova, M Maynadie, A Staines, T Lightfoot, S Crouch, A Smith, E Roman, WR Diver, K Offit, A Zelenetz, RJ Klein, DJ Villano, T Zheng, Y Zhang, TR Holford, A Kricker, J Turner, MC Southey, J Clavel, J Virtamo, S Weinstein, E Riboli, P Vineis, R Kaaks, D Trichopoulos, RC Vermeulen, H Boeing, A Tjonneland, E Angelucci, S Di Lollo, M Rais, BM Birmann, F Laden, E Giovannucci, P Kraft, J Huang, B Ma, Y Ye, BC Chiu, J Sampson, L Liang, JH Park, CC Chung, DD Weisenburger, N Chatterjee, JF Fraumeni, SL Slager, X Wu, S de Sanjose, KE Smedby, G Salles, CF Skibola, N Rothman, SJ Chanock
This set describes genes whose transcription is down-regulated in the whole blood of COVID-19 patients versus healthy donors. Genes listed in table S2 were entered using the core ENSEMBL Gene identifiers. Values are the reported log2 fold-change.
Authors:
Anna C Aschenbrenner, Maria Mouktaroudi, Benjamin Krämer, Marie Oestreich, Nikolaos Antonakos, Melanie Nuesch-Germano, Konstantina Gkizeli, Lorenzo Bonaguro, Nico Reusch, Kevin Baßler, Maria Saridaki, Rainer Knoll, Tal Pecht, Theodore S Kapellos, Sarandia Doulou, Charlotte Kröger, Miriam Herbert, Lisa Holsten, Arik Horne, Ioanna D Gemünd, Nikoletta Rovina, Shobhit Agrawal, Kilian Dahm, Martina van Uelft, Anna Drews, Lena Lenkeit, Niklas Bruse, Jelle Gerretsen, Jannik Gierlich, Matthias Becker, Kristian Händler, Michael Kraut, Heidi Theis, Simachew Mengiste, Elena De Domenico, Jonas Schulte-Schrepping, Lea Seep, Jan Raabe, Christoph Hoffmeister, Michael ToVinh, Verena Keitel, Gereon Rieke, Valentina Talevi, Dirk Skowasch, N Ahmad Aziz, Peter Pickkers, Frank L van de Veerdonk, Mihai G Netea, Joachim L Schultze, Matthijs Kox, Monique M B Breteler, Jacob Nattermann, Antonia Koutsoukou, Evangelos J Giamarellos-Bourboulis, Thomas Ulas,
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