QTL associated with methamphetamine response QTL 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (125309605)
Authors:
Palmer AA, Verbitsky M, Suresh R, Kamens HM, Reed CL, Li N, Burkhart-Kasch S, McKinnon CS, Belknap JK, Gilliam TC, Phillips TJ
QTL associated with thymic lymphoma susceptibility 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (93726231)
Authors:
Kodama Y, Yoshikai Y, Tamura Y, Wakana S, Takagi R, Niwa O, Kominami R
Differential gene expression in nucleus accumbens somatostatin interneurons_cocaine_mice_pvalue
Description:
To characterize transcriptional alterations that cocaine induces in these cells, we perform cell type-specific RNA-sequencing on FACS-isolated nuclei of somatostatin interneurons and identified 1100 DETs enriched for processes related to neural plasticity. To profile the entire (non poly-A selected) transcriptome of NAc somatostatin interneurons, we generated a transgenic reporter line (SST-TLG498 mice) to label the nuclei of these cells with a modified form of EGFP that is retained in the nuclear membrane (EGFP-F)22, enabling their isolation from NAc dissections using FACS. We succeeded in FACS-isolating nuclei suitable for RNA-sequencing from individual SST-TLG498 mice. We proceeded with differential expression analysis of the RNA-sequencing data to identify differentially expressed transcripts (DETs) in NAc somatostatin interneurons in response to repeated cocaine exposure: 778 transcripts were upregulated by cocaine and 322 were downregulated.
Authors:
Efrain A Ribeiro, Marine Salery, Joseph R Scarpa, Erin S Calipari, Peter J Hamilton, Stacy M Ku, Hope Kronman, Immanuel Purushothaman, Barbara Juarez, Mitra Heshmati, Marie Doyle, Casey Lardner, Dominicka Burek, Ana Strat, Stephen Pirpinias, Ezekiell Mouzon, Ming-Hu Han, Rachael L Neve, Rosemary C Bagot, Andrew Kasarskis, Ja Wook Koo, Eric J Nestler
QTL associated with circulating hormone level QTL 11. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (125309605)
QTL associated with "early growth rate, direct effect 1". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (112715734)
QTL associated with dopamine-induced hypothermia. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (115413178)
Authors:
Stoddart CW, Martin-Iverson MT, Jablensky A, Urosevi N
QTL associated with lymph node cytotoxic T lymphocyte percentage 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (96820800)
QTL associated with circulating hormone level QTL 14. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (93561953)
Average rotarod training latency Chr# 5 rs13478110 (9741228) with right flanking marker rs13478092(3595407) and left marker rs3718776 (150393227). This was mapped in 300 + (b6x129)F2 mice.
QTL associated with body weight females and males day 10. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (126842654)
QTL associated with correlation in cytokine production 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (132603914)
Authors:
Kosarov M, Havelkov H, Krulov M, Demant P, Lipoldov M
QTL associated with dextran sodium sulfate induced colitis QTL1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (132580851)
QTL associated with Theiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 7. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (130061274)
Authors:
Butterfield RJ, Roper RJ, Rhein DM, Melvold RW, Haynes L, Ma RZ, Doerge RW, Teuscher C
QTL associated with activity-distance traveled 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (113601539)
QTL associated with autoimmune extremity vasculitis in MRL mice 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (119175776)
Authors:
Yamada A, Miyazaki T, Lu LM, Ono M, Ito MR, Terada M, Mori S, Hata K, Nozaki Y, Nakatsuru S, Nakamura Y, Onji M, Nose M
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