QTL associated with radiation-induced apoptosis 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (76902079)
Differential gene expression in nucleus accumbens somatostatin interneurons_cocaine_mice_pvalue
Description:
To characterize transcriptional alterations that cocaine induces in these cells, we perform cell type-specific RNA-sequencing on FACS-isolated nuclei of somatostatin interneurons and identified 1100 DETs enriched for processes related to neural plasticity. To profile the entire (non poly-A selected) transcriptome of NAc somatostatin interneurons, we generated a transgenic reporter line (SST-TLG498 mice) to label the nuclei of these cells with a modified form of EGFP that is retained in the nuclear membrane (EGFP-F)22, enabling their isolation from NAc dissections using FACS. We succeeded in FACS-isolating nuclei suitable for RNA-sequencing from individual SST-TLG498 mice. We proceeded with differential expression analysis of the RNA-sequencing data to identify differentially expressed transcripts (DETs) in NAc somatostatin interneurons in response to repeated cocaine exposure: 778 transcripts were upregulated by cocaine and 322 were downregulated.
Authors:
Efrain A Ribeiro, Marine Salery, Joseph R Scarpa, Erin S Calipari, Peter J Hamilton, Stacy M Ku, Hope Kronman, Immanuel Purushothaman, Barbara Juarez, Mitra Heshmati, Marie Doyle, Casey Lardner, Dominicka Burek, Ana Strat, Stephen Pirpinias, Ezekiell Mouzon, Ming-Hu Han, Rachael L Neve, Rosemary C Bagot, Andrew Kasarskis, Ja Wook Koo, Eric J Nestler
QTL associated with pristane induced arthritis 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (96885628)
Authors:
Jensen JR, Peters LC, Borrego A, Ribeiro OG, Cabrera WH, Starobinas N, Siqueira M, Ibaez OC, De Franco M
QTL associated with susceptibility to Salmonella typhimurium antigens 5. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (96885628)
Authors:
de Souza CM, Morel L, Cabrera WH, Starobinas N, Ribeiro OG, Siqueira M, Ibaez OM, De Franco M
QTL associated with cystic fibrosis survival to weaning 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (100779519)
QTL associated with collagen induced arthritis QTL 5. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (82943273)
Authors:
Johannesson M, Olsson LM, Lindqvist AK, Mller S, Koczan D, Wester-Rosenlf L, Thiesen HJ, Ibrahim S, Holmdahl R
QTL associated with experimental allergic encephalomyelitis susceptibility 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (96445337)
QTL associated with epistatic circling A C57L/J 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (82366294)
Authors:
Cryns K, Van Spaendonck MP, Flothmann K, van Alphen AM, Van De Heyning PH, Timmermans JP, De Zeeuw CI, Van Camp G
QTL associated with induction of brown adipocytes 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (99043650)
QTL associated with periosteal circumference and femur length 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (97981259)
Authors:
Masinde GL, Wergedal J, Davidson H, Mohan S, Li R, Li X, Baylink DJ
QTL associated with proteoglycan induced arthritis 26. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (109147135)
Authors:
Glant TT, Adarichev VA, Nesterovitch AB, Szanto S, Oswald JP, Jacobs JJ, Firneisz G, Zhang J, Finnegan A, Mikecz K
QTL associated with systematic lupus erythematosus susceptibility 11. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (87105519)
Authors:
Haywood ME, Hogarth MB, Slingsby JH, Rose SJ, Allen PJ, Thompson EM, Maibaum MA, Chandler P, Davies KA, Simpson E, Walport MJ, Morley BJ
QTL associated with systemic lupus erythmatosus suppressor 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (78636676)
Authors:
Haywood ME, Gabriel L, Rose SJ, Rogers NJ, Izui S, Morley BJ
QTL associated with tibia bone quality traits 4. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (101827765)
Authors:
Jiao Y, Chiu H, Fan Z, Jiao F, Eckstein EC, Beamer WG, Gu W
QTL associated with total cholesterol level 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (100269519)
Authors:
Shike T, Hirose S, Kobayashi M, Funabiki K, Shirai T, Tomino Y
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