QTL associated with susceptibility to lung cancer 21. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (134229745)
QTL associated with susceptibility to lung cancer 6. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (137502609)
QTL associated with lung tumor shape-determining 4. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (137502609)
QTL associated with fluctuating asymmetry QTL 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (150044898)
Authors:
Zhang S, Lou Y, Amstein TM, Anyango M, Mohibullah N, Osoti A, Stancliffe D, King R, Iraqi F, Gershenfeld HK
Differential gene expression in nucleus accumbens somatostatin interneurons_cocaine_mice_pvalue
Description:
To characterize transcriptional alterations that cocaine induces in these cells, we perform cell type-specific RNA-sequencing on FACS-isolated nuclei of somatostatin interneurons and identified 1100 DETs enriched for processes related to neural plasticity. To profile the entire (non poly-A selected) transcriptome of NAc somatostatin interneurons, we generated a transgenic reporter line (SST-TLG498 mice) to label the nuclei of these cells with a modified form of EGFP that is retained in the nuclear membrane (EGFP-F)22, enabling their isolation from NAc dissections using FACS. We succeeded in FACS-isolating nuclei suitable for RNA-sequencing from individual SST-TLG498 mice. We proceeded with differential expression analysis of the RNA-sequencing data to identify differentially expressed transcripts (DETs) in NAc somatostatin interneurons in response to repeated cocaine exposure: 778 transcripts were upregulated by cocaine and 322 were downregulated.
Authors:
Efrain A Ribeiro, Marine Salery, Joseph R Scarpa, Erin S Calipari, Peter J Hamilton, Stacy M Ku, Hope Kronman, Immanuel Purushothaman, Barbara Juarez, Mitra Heshmati, Marie Doyle, Casey Lardner, Dominicka Burek, Ana Strat, Stephen Pirpinias, Ezekiell Mouzon, Ming-Hu Han, Rachael L Neve, Rosemary C Bagot, Andrew Kasarskis, Ja Wook Koo, Eric J Nestler
QTL associated with insulin dependent diabetes susceptibility 9. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (124439115)
Authors:
Cox SL, Stolp J, Hallahan NL, Counotte J, Zhang W, Serreze DV, Basten A, Silveira PA
QTL associated with body weight at 8 weeks QTL 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (136693037)
QTL associated with circulating hormone level QTL 16. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (138171253)
QTL associated with light induced retinal degeneration 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (141401276)
Authors:
Danciger M, Lyon J, Worrill D, Hoffman S, Lem J, Reme CE, Wenzel A, Grimm C
QTL associated with bone response to mechanical loading 13. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (150944103)
QTL associated with autoimmune renal vasculitis 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (124575015)
Authors:
Qu WM, Miyazaki T, Terada M, Lu LM, Nishihara M, Yamada A, Mori S, Nakamura Y, Ogasawara H, Yazawa C, Nakatsuru S, Nose M
QTL associated with dystrophic cardiac calcinosis 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (127792502)
QTL associated with insulin dependent diabetes susceptibility 25. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (133341830)
QTL associated with recognized antigen from MCA-induced tumor 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (133923341)
QTL associated with SGC/Knj cross B6 QTL 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (133341830)
Authors:
Hamano Y, Tsukamoto K, Abe M, Sun GD, Zhang D, Fujii H, Matsuoka S, Tanaka M, Ishida-Okawara A, Tachikawa H, Nishimura H, Tokunaka K, Hirose S, Suzuki K
QTL associated with triglyceride level suppressor 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (127039007)
Authors:
Shike T, Hirose S, Kobayashi M, Funabiki K, Shirai T, Tomino Y
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