GWAS: pulmonary function measurement, FEV/FEC ratio
Description:
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Pulmonary function. The EFO term pulmonary function measurement, FEV/FEC ratio was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
M Soler Artigas, DW Loth, LV Wain, SA Gharib, M Obeidat, W Tang, G Zhai, JH Zhao, AV Smith, JE Huffman, E Albrecht, CM Jackson, DM Evans, G Cadby, M Fornage, A Manichaikul, LM Lopez, T Johnson, MC Aldrich, T Aspelund, I Barroso, H Campbell, PA Cassano, DJ Couper, G Eiriksdottir, N Franceschini, M Garcia, C Gieger, GK Gislason, I Grkovic, CJ Hammond, DB Hancock, TB Harris, A Ramasamy, SR Heckbert, M Heliövaara, G Homuth, PG Hysi, AL James, S Jankovic, BR Joubert, S Karrasch, N Klopp, B Koch, SB Kritchevsky, LJ Launer, Y Liu, LR Loehr, K Lohman, RJ Loos, T Lumley, KA Al Balushi, WQ Ang, RG Barr, J Beilby, JD Blakey, M Boban, V Boraska, J Brisman, JR Britton, GG Brusselle, C Cooper, I Curjuric, S Dahgam, IJ Deary, S Ebrahim, M Eijgelsheim, C Francks, D Gaysina, R Granell, X Gu, JL Hankinson, R Hardy, SE Harris, J Henderson, A Henry, AD Hingorani, A Hofman, PG Holt, J Hui, ML Hunter, M Imboden, KA Jameson, SM Kerr, I Kolcic, F Kronenberg, JZ Liu, J Marchini, T McKeever, AD Morris, AC Olin, DJ Porteous, DS Postma, SS Rich, SM Ring, F Rivadeneira, T Rochat, AA Sayer, I Sayers, PD Sly, GD Smith, A Sood, JM Starr, AG Uitterlinden, JM Vonk, SG Wannamethee, PH Whincup, C Wijmenga, OD Williams, A Wong, M Mangino, KD Marciante, WL McArdle, B Meibohm, AC Morrison, KE North, E Omenaas, LJ Palmer, KH Pietiläinen, I Pin, O Pola Sbreve Ek, A Pouta, BM Psaty, AL Hartikainen, T Rantanen, S Ripatti, JI Rotter, I Rudan, AR Rudnicka, H Schulz, SY Shin, TD Spector, I Surakka, V Vitart, H Völzke, NJ Wareham, NM Warrington, HE Wichmann, SH Wild, JB Wilk, M Wjst, AF Wright, L Zgaga, T Zemunik, CE Pennell, F Nyberg, D Kuh, JW Holloway, HM Boezen, DA Lawlor, RW Morris, N Probst-Hensch, J Kaprio, JF Wilson, C Hayward, M Kähönen, J Heinrich, AW Musk, DL Jarvis, S Gläser, MR Järvelin, BH Ch Stricker, P Elliott, GT O'Connor, DP Strachan, SJ London, IP Hall, V Gudnason, MD Tobin
Cerebellum Gene Expression Correlates for NEPDIST45 measured in BXD RI Females obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The NEPDIST45 measures Novel environment locomotion (cm) 30-45 min in the periphery under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Neocortex Gene Expression Correlates for COCA_TIME_PCT_CHANGE measured in BXD RI Females obtained using GeneNetwork Neocortex ILM6v1.1 (Feb08) RankInv. The COCA_TIME_PCT_CHANGE measures Cocaine CPP - difference in percent test time spent relative to preconditioning under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
QTL for ethanol withdrawal on Chr13 at D13Ncvs35 (71.29 Mbp , Build 37)
Description:
ethanol withdrawal spans 46.29 - 96.29 Mbp (NCBI Build 37) on Chr13. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Genes associated with Homo sapiens that interact with the MeSH term '8-Bromo Cyclic Adenosine Monophosphate' (D015124). Incorporates data from 233 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Ovis aries that interact with the MeSH term 'Progesterone' (D011374). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with nan that interact with the MeSH term 'Aluminum' (D000535). Incorporates data from 24 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
QTL associated with spontaneous crescentic glomerulonephritis QTL 5. The confidence interval is Chr13:35968794-96872609 bp,+strand
Authors:
Hamano Y, Tsukamoto K, Abe M, Sun GD, Zhang D, Fujii H, Matsuoka S, Tanaka M, Ishida-Okawara A, Tachikawa H, Nishimura H, Tokunaka K, Hirose S, Suzuki K
QTL associated with Angiostrongylus costaricensis nematode susceptibility 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (53042863)
QTL associated with Avp transcript abundance QTL 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (85473357)
QTL associated with castaneus 10 week body weight 4. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (72374309)
QTL associated with cystic fibrosis body weight 5. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (55673906)
QTL associated with cocaine induced activation 11. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (54579545)
QTL associated with "cerebellum pattern fissures, declival 5". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (56582797)
QTL associated with circadian period of locomotor activity 11. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (55673906)
Authors:
Hofstetter JR, Trofatter JA, Kernek KL, Nurnberger JI, Mayeda AR
QTL associated with Crh transcript abundance QTL 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (56786703)
QTL associated with delta power in slow-wave sleep 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (85473357)
QTL associated with experimental allergic encephalomyelitis susceptibility 13. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (67271283)
Authors:
Butterfield RJ, Blankenhorn EP, Roper RJ, Zachary JF, Doerge RW, Sudweeks J, Rose J, Teuscher C
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