DESCRIPTION:

QTL associated with cystic fibrosis body weight 5. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (55673906)

LABEL:

QTL-Cfbw5-Mouse-Chr 13

SCORE TYPE:

Binary

DATE ADDED:

2012-04-02

DATE UPDATED:

2020-05-06

SPECIES:

URI:

http://www.informatics.jax.org/searches/accession_report.cgi?id=MGI:2661707

AUTHORS:

Nadeau JH

TITLE:

Modifier genes and protective alleles in humans and mice.

JOURNAL:

Current opinion in genetics & development Jun 2003, Vol 13, pp. 290-5

ABSTRACT:

Interest in modifier genes is growing rapidly because of their ability to modulate the phenotype of individuals with monogenic and multigenic traits and diseases. A neglected class of modifiers is protective alleles that can suppress disease in otherwise susceptible individuals. Together these modifier genes and protective alleles provide important glimpses into the molecular and cellular basis for the functional networks that provide robustness and homeostasis in complex biological systems. PUBMED: 12787792
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