List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Schizophrenia. The EFO term schizophrenia was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
S Ripke, C O'Dushlaine, K Chambert, JL Moran, AK Kähler, S Akterin, SE Bergen, AL Collins, JJ Crowley, M Fromer, Y Kim, SH Lee, PK Magnusson, N Sanchez, EA Stahl, S Williams, NR Wray, K Xia, F Bettella, AD Borglum, BK Bulik-Sullivan, P Cormican, N Craddock, C de Leeuw, N Durmishi, M Gill, V Golimbet, ML Hamshere, P Holmans, DM Hougaard, KS Kendler, K Lin, DW Morris, O Mors, PB Mortensen, BM Neale, FA O'Neill, MJ Owen, MP Milovancevic, D Posthuma, J Powell, AL Richards, BP Riley, D Ruderfer, D Rujescu, E Sigurdsson, T Silagadze, AB Smit, H Stefansson, S Steinberg, J Suvisaari, S Tosato, M Verhage, JT Walters, DF Levinson, PV Gejman, KS Kendler, C Laurent, BJ Mowry, MC O'Donovan, MJ Owen, AE Pulver, BP Riley, SG Schwab, DB Wildenauer, F Dudbridge, P Holmans, J Shi, M Albus, M Alexander, D Campion, D Cohen, D Dikeos, J Duan, P Eichhammer, S Godard, M Hansen, FB Lerer, KY Liang, W Maier, J Mallet, DA Nertney, G Nestadt, N Norton, FA O'Neill, GN Papadimitriou, R Ribble, AR Sanders, JM Silverman, D Walsh, NM Williams, B Wormley, MJ Arranz, S Bakker, S Bender, E Bramon, D Collier, B Crespo-Facorro, J Hall, C Iyegbe, A Jablensky, RS Kahn, L Kalaydjieva, S Lawrie, CM Lewis, K Lin, DH Linszen, I Mata, A McIntosh, RM Murray, RA Ophoff, J Powell, D Rujescu, J Van Os, M Walshe, M Weisbrod, D Wiersma, P Donnelly, I Barroso, JM Blackwell, E Bramon, MA Brown, JP Casas, AP Corvin, P Deloukas, A Duncanson, J Jankowski, HS Markus, CG Mathew, CN Palmer, R Plomin, A Rautanen, SJ Sawcer, RC Trembath, AC Viswanathan, NW Wood, CC Spencer, G Band, C Bellenguez, C Freeman, G Hellenthal, E Giannoulatou, M Pirinen, RD Pearson, A Strange, Z Su, D Vukcevic, P Donnelly, C Langford, SE Hunt, S Edkins, R Gwilliam, H Blackburn, SJ Bumpstead, S Dronov, M Gillman, E Gray, N Hammond, A Jayakumar, OT McCann, J Liddle, SC Potter, R Ravindrarajah, M Ricketts, A Tashakkori-Ghanbaria, MJ Waller, P Weston, S Widaa, P Whittaker, I Barroso, P Deloukas, CG Mathew, JM Blackwell, MA Brown, AP Corvin, MI McCarthy, CC Spencer, E Bramon, AP Corvin, MC O'Donovan, K Stefansson, E Scolnick, S Purcell, SA McCarroll, P Sklar, CM Hultman, PF Sullivan
Data from GEO GSE194368 and analyzed using GEO2R, only top gene shown. Authors identified transcriptional adaptations of GR signaling in the amygdala of humans with OUD. Thus, GRs, their coregulators and downstream systems may represent viable therapeutic targets to treat the “stress side” of OUD.
Authors:
Stephanie A Carmack, Janaina C M Vendruscolo, M Adrienne McGinn, Jorge Miranda-Barrientos, Vez Repunte-Canonigo, Gabriel D Bosse, Daniele Mercatelli, Federico M Giorgi, Yu Fu, Anthony J Hinrich, Francine M Jodelka, Karen Ling, Robert O Messing, Randall T Peterson, Frank Rigo, Scott Edwards, Pietro P Sanna, Marisela Morales, Michelle L Hastings, George F Koob, Leandro F Vendruscolo
Hippocampus Gene Expression Correlates for LM_PAIR3 measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The LM_PAIR3 measures Activity during 3rd tone shock pairing under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Genes associated with Homo sapiens that interact with the MeSH term 'Carbamazepine' (D002220). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '2,2',4,4'-tetrabromodiphenyl ether' (C511295). Incorporates data from 6 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Plant Extracts' (D010936). Incorporates data from 489 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Valproic Acid' (D014635). Incorporates data from 1238 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Vanadates' (D014638). Incorporates data from 150 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
QTL associated with Avp transcript abundance QTL 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (85473357)
QTL associated with catalepsy susceptibility 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (119618032)
Authors:
Kulikov AV, Bazovkina DV, Kondaurova EM, Popova NK
QTL associated with collagen induced arthritis 10. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (102207023)
Authors:
Glant TT, Adarichev VA, Nesterovitch AB, Szanto S, Oswald JP, Jacobs JJ, Firneisz G, Zhang J, Finnegan A, Mikecz K
QTL associated with directional asymmetry QTL 9. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (119863504)
QTL associated with delta power in slow-wave sleep 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (85473357)
QTL associated with epistatic circling C C57L/J 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (85045485)
Authors:
Cryns K, Van Spaendonck MP, Flothmann K, van Alphen AM, Van De Heyning PH, Timmermans JP, De Zeeuw CI, Van Camp G
QTL associated with ethanol induced low dose activation 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (111229752)
QTL associated with granulosa cell tumorigenesis 9. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (112690498)
Authors:
Dorward AM, Shultz KL, Horton LG, Li R, Churchill GA, Beamer WG
QTL associated with wound healing/regeneration 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (111528941)
Authors:
Heber-Katz E, Chen P, Clark L, Zhang XM, Troutman S, Blankenhorn EP
QTL associated with wound healing/regeneration 8. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (85045485)
Authors:
Heber-Katz E, Leferovich JM, Bedelbaeva K, Gourevitch D
QTL associated with postnatal body weight growth 17. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (101509507)
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