List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Response to mTOR inhibitor (everolimus). The EFO term response to mTOR inhibitor was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
J Jiang, BL Fridley, Q Feng, RP Abo, A Brisbin, A Batzler, G Jenkins, PA Long, L Wang
Pathway Commons (PC) Geneset. This geneset contains genes that participate in the "mTOR signaling pathway" pathway. This set was automatically constructed using the PC API.
The original source of this geneset is pid.
gene2pc v. 0.1.0
Last updated 2015.08.31
Kyoto Encyclopedia of Genes and Genomes (KEGG) Geneset. This geneset contains genes that participate in the "mTOR signaling pathway" pathway. This set was automatically constructed using the KEGG API and enumerating all rat pathways.
gene2kegg v. 0.1.1
Last updated 2015.09.10
Kyoto Encyclopedia of Genes and Genomes (KEGG) Geneset. This geneset contains genes that participate in the "mTOR signaling pathway" pathway. This set was automatically constructed using the KEGG API and enumerating all mouse pathways.
gene2kegg v. 0.1.1
Last updated 2015.09.10
Kyoto Encyclopedia of Genes and Genomes (KEGG) Geneset. This geneset contains genes that participate in the "mTOR signaling pathway" pathway. This set was automatically constructed using the KEGG API and enumerating all human pathways.
gene2kegg v. 0.1.1
Last updated 2015.09.10
Kyoto Encyclopedia of Genes and Genomes (KEGG) Geneset. This geneset contains genes that participate in the "mTOR signaling pathway" pathway. This set was automatically constructed using the KEGG API and enumerating all zebrafish pathways.
gene2kegg v. 0.1.2
Last updated 2018.01.17
"A protein complex that contains the mTOR (mammalian target of rapamycin) serine/threonine kinase, the peptidyl-prolyl cis-trans isomerase FKBP12 (FKBP1A) and rapamycin (sirolimus)." [GOC:sl, PMID:20005306, PMID:7822316]
"A protein complex that contains the mTOR (mammalian target of rapamycin) serine/threonine kinase, the peptidyl-prolyl cis-trans isomerase FKBP12 (FKBP1A) and rapamycin (sirolimus)." [GOC:sl, PMID:20005306, PMID:7822316]
Kyoto Encyclopedia of Genes and Genomes (KEGG) Geneset. This geneset contains genes that participate in the "mTOR signaling pathway" pathway. This set was automatically constructed using the KEGG API and enumerating all rhesus monkey pathways.
gene2kegg v. 0.1.1
Last updated 2015.09.10
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Corneal curvature. The EFO term corneal topography was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
P Chen, M Miyake, Q Fan, J Liao, K Yamashiro, MK Ikram, M Chew, EN Vithana, CC Khor, T Aung, ES Tai, TY Wong, YY Teo, N Yoshimura, SM Saw, CY Cheng
18 genes differentially expressed in the prefrontal cortex (PFC) following morphine self-administration normalized to vehicle self-administration (VhSA) in adult male Lewis rats. Expression levels were measured with RT-qPCR. Values presented are fold-change from Table 1.
Authors:
Marcos Ucha, Santiago M Coria, Adrián E Núñez, Raquel Santos-Toscano, David Roura-Martínez, Javier Fernández-Ruiz, Alejandro Higuera-Matas, Emilio Ambrosio
18 genes differentially expressed in the nucleus accumbens (NAcc) following morphine self-administration normalized to vehicle self-administration (VhSA) in adult male Lewis rats. Expression levels were measured with RT-qPCR. Values presented are fold-change from Table 1.
Authors:
Marcos Ucha, Santiago M Coria, Adrián E Núñez, Raquel Santos-Toscano, David Roura-Martínez, Javier Fernández-Ruiz, Alejandro Higuera-Matas, Emilio Ambrosio
18 genes differentially expressed in the amygdala (Amy) following morphine self-administration normalized to vehicle self-administration (VhSA) in adult male Lewis rats. Expression levels were measured with RT-qPCR. Values presented are fold-change taken from table Table 1.
Authors:
Marcos Ucha, Santiago M Coria, Adrián E Núñez, Raquel Santos-Toscano, David Roura-Martínez, Javier Fernández-Ruiz, Alejandro Higuera-Matas, Emilio Ambrosio
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Monobrow thickness. The EFO term facial hair thickness measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
K Adhikari, T Fontanil, S Cal, J Mendoza-Revilla, M Fuentes-Guajardo, JC Chacón-Duque, F Al-Saadi, JA Johansson, M Quinto-Sanchez, V Acuña-Alonzo, C Jaramillo, W Arias, R Barquera Lozano, G Macín Pérez, J Gómez-Valdés, H Villamil-Ramírez, T Hunemeier, V Ramallo, CC Silva de Cerqueira, M Hurtado, V Villegas, V Granja, C Gallo, G Poletti, L Schuler-Faccini, FM Salzano, MC Bortolini, S Canizales-Quinteros, F Rothhammer, G Bedoya, R Gonzalez-José, D Headon, C López-Otín, DJ Tobin, D Balding, A Ruiz-Linares
The total transcriptome including genes that are differentially expressed in cocaine addicts compared to control subjects. Post-mortem brain samples were collected from the dorsolateral prefrontal cortex (dlPFC) of the cocaine addict group and the control group. To assess gene expression, RNA-seq was performed. Data taken from Supplementary Table 2. Values presented are k.diff values. Data available from GEO with accession number GSE99349."
Authors:
Efrain A Ribeiro, Joseph R Scarpa, Susanna P Garamszegi, Andrew Kasarskis, Deborah C Mash, Eric J Nestler
Data from GEO GSE194368 and analyzed using GEO2R, only top gene shown. Authors identified transcriptional adaptations of GR signaling in the amygdala of humans with OUD. Thus, GRs, their coregulators and downstream systems may represent viable therapeutic targets to treat the “stress side” of OUD.
Authors:
Stephanie A Carmack, Janaina C M Vendruscolo, M Adrienne McGinn, Jorge Miranda-Barrientos, Vez Repunte-Canonigo, Gabriel D Bosse, Daniele Mercatelli, Federico M Giorgi, Yu Fu, Anthony J Hinrich, Francine M Jodelka, Karen Ling, Robert O Messing, Randall T Peterson, Frank Rigo, Scott Edwards, Pietro P Sanna, Marisela Morales, Michelle L Hastings, George F Koob, Leandro F Vendruscolo
Neocortex Gene Expression Correlates for HP_LATENCY measured in BXD RI Females & Males obtained using GeneNetwork Neocortex ILM6v1.1 (Feb08) RankInv. The HP_LATENCY measures Thermal Nociception Hot Plate Latency under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for AMCNT105 measured in BXD RI Females & Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The AMCNT105 measures Morphine photocell counts minutes 90-105 under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for AMCNT120 measured in BXD RI Females & Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The AMCNT120 measures Morphine photocell counts minutes 105-120 under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for AMCNT120 measured in BXD RI Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The AMCNT120 measures Morphine photocell counts minutes 105-120 under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for AMCNT135 measured in BXD RI Females & Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The AMCNT135 measures Morphine photocell counts minutes 120-135 under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
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