List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Alzheimer's disease (late onset). The EFO term Alzheimers disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
AC Naj, G Jun, GW Beecham, LS Wang, BN Vardarajan, J Buros, PJ Gallins, JD Buxbaum, GP Jarvik, PK Crane, EB Larson, TD Bird, BF Boeve, NR Graff-Radford, PL De Jager, D Evans, JA Schneider, MM Carrasquillo, N Ertekin-Taner, SG Younkin, C Cruchaga, JS Kauwe, P Nowotny, P Kramer, J Hardy, MJ Huentelman, AJ Myers, MM Barmada, FY Demirci, CT Baldwin, RC Green, E Rogaeva, P St George-Hyslop, SE Arnold, R Barber, T Beach, EH Bigio, JD Bowen, A Boxer, JR Burke, NJ Cairns, CS Carlson, RM Carney, SL Carroll, HC Chui, DG Clark, J Corneveaux, CW Cotman, JL Cummings, C DeCarli, ST DeKosky, R Diaz-Arrastia, M Dick, DW Dickson, WG Ellis, KM Faber, KB Fallon, MR Farlow, S Ferris, MP Frosch, DR Galasko, M Ganguli, M Gearing, DH Geschwind, B Ghetti, JR Gilbert, S Gilman, B Giordani, JD Glass, JH Growdon, RL Hamilton, LE Harrell, E Head, LS Honig, CM Hulette, BT Hyman, GA Jicha, LW Jin, N Johnson, J Karlawish, A Karydas, JA Kaye, R Kim, EH Koo, NW Kowall, JJ Lah, AI Levey, AP Lieberman, OL Lopez, WJ Mack, DC Marson, F Martiniuk, DC Mash, E Masliah, WC McCormick, SM McCurry, AN McDavid, AC McKee, M Mesulam, BL Miller, CA Miller, JW Miller, JE Parisi, DP Perl, E Peskind, RC Petersen, WW Poon, JF Quinn, RA Rajbhandary, M Raskind, B Reisberg, JM Ringman, ED Roberson, RN Rosenberg, M Sano, LS Schneider, W Seeley, ML Shelanski, MA Slifer, CD Smith, JA Sonnen, S Spina, RA Stern, RE Tanzi, JQ Trojanowski, JC Troncoso, VM Van Deerlin, HV Vinters, JP Vonsattel, S Weintraub, KA Welsh-Bohmer, J Williamson, RL Woltjer, LB Cantwell, BA Dombroski, D Beekly, KL Lunetta, ER Martin, MI Kamboh, AJ Saykin, EM Reiman, DA Bennett, JC Morris, TJ Montine, AM Goate, D Blacker, DW Tsuang, H Hakonarson, WA Kukull, TM Foroud, JL Haines, R Mayeux, MA Pericak-Vance, LA Farrer, GD Schellenberg
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Alzheimer's disease in APOE e4- carriers. The EFO term Alzheimers disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
G Jun, CA Ibrahim-Verbaas, M Vronskaya, JC Lambert, J Chung, AC Naj, BW Kunkle, LS Wang, JC Bis, C Bellenguez, D Harold, KL Lunetta, AL Destefano, B Grenier-Boley, R Sims, GW Beecham, AV Smith, V Chouraki, KL Hamilton-Nelson, MA Ikram, N Fievet, N Denning, ER Martin, H Schmidt, Y Kamatani, ML Dunstan, O Valladares, AR Laza, D Zelenika, A Ramirez, TM Foroud, SH Choi, A Boland, T Becker, WA Kukull, SJ van der Lee, F Pasquier, C Cruchaga, D Beekly, AL Fitzpatrick, O Hanon, M Gill, R Barber, V Gudnason, D Campion, S Love, DA Bennett, N Amin, C Berr, M Tsolaki, JD Buxbaum, OL Lopez, V Deramecourt, NC Fox, LB Cantwell, L Tárraga, C Dufouil, J Hardy, PK Crane, G Eiriksdottir, D Hannequin, R Clarke, D Evans, TH Mosley, L Letenneur, C Brayne, W Maier, P De Jager, V Emilsson, JF Dartigues, H Hampel, MI Kamboh, RF de Bruijn, C Tzourio, P Pastor, EB Larson, JI Rotter, MC O'Donovan, TJ Montine, MA Nalls, S Mead, EM Reiman, PV Jonsson, C Holmes, PH St George-Hyslop, M Boada, P Passmore, JR Wendland, R Schmidt, K Morgan, AR Winslow, JF Powell, M Carasquillo, SG Younkin, J Jakobsdóttir, JS Kauwe, KC Wilhelmsen, D Rujescu, MM Nöthen, A Hofman, L Jones, JL Haines, BM Psaty, C Van Broeckhoven, P Holmans, LJ Launer, R Mayeux, M Lathrop, AM Goate, V Escott-Price, S Seshadri, MA Pericak-Vance, P Amouyel, J Williams, CM van Duijn, GD Schellenberg, LA Farrer
QTL for METH responses for body temperature on Chr19 at Gnblps1 (0.00 Mbp , Build 37)
Description:
METH responses for body temperature spans 0.00 - 25.00 Mbp (NCBI Build 37) on Chr19. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for body temperature on Chr19 at Lybp2 (2.15 Mbp , Build 37)
Description:
METH responses for body temperature spans 0.00 - 27.15 Mbp (NCBI Build 37) on Chr19. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for body temperature on Chr19 at Pomc-2 (14.21 Mbp , Build 37)
Description:
METH responses for body temperature spans 0.00 - 39.21 Mbp (NCBI Build 37) on Chr19. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for body temperature on Chr19 at Lpc1 (23.27 Mbp , Build 37)
Description:
METH responses for body temperature spans 0.00 - 48.27 Mbp (NCBI Build 37) on Chr19. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for alcohol preference locus on Chr19 at D19Mit46 (29.54 Mbp , Build 37)
Description:
alcohol preference locus spans 4.54 - 54.54 Mbp (NCBI Build 37) on Chr19. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for alcohol preference locus on Chr19 at D19Mit46 (29.54 Mbp , Build 37)
Description:
alcohol preference locus spans 4.54 - 54.54 Mbp (NCBI Build 37) on Chr19. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Genes associated with Oryctolagus cuniculus that interact with the MeSH term 'Ionomycin' (D015759). Incorporates data from 6 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Copper Sulfate' (D019327). Incorporates data from 72 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '3,4,5,3',4'-pentachlorobiphenyl' (C023035). Incorporates data from 644 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Equus caballus that interact with the MeSH term 'Castor Oil' (D002368). Incorporates data from 887 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Oryctolagus cuniculus that interact with the MeSH term 'Lipopolysaccharides' (D008070). Incorporates data from 23 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Oryctolagus cuniculus that interact with the MeSH term 'Tetradecanoylphorbol Acetate' (D013755). Incorporates data from 2 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Grape Seed Proanthocyanidins' (C511402). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Nickel' (D009532). Incorporates data from 166 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Catechin' (D002392). Incorporates data from 12 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Calcitriol' (D002117). Incorporates data from 260 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Benzo(a)pyrene' (D001564). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Acetaminophen' (D000082). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
QTL associated with "alcohol preference locus 23, male specific". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (33009697)
QTL associated with "alcohol preference locus 24, female specific". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (33009697)
QTL associated with bone response to mechanical loading 12. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (3645155)
Authors:
Kesavan C, Baylink DJ, Kapoor S, Mohan S
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