DESCRIPTION:

QTL associated with bitterness sensitivity 4. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (20420342)

LABEL:

QTL-Bits4-Mouse-Chr 19

SCORE TYPE:

Binary

DATE ADDED:

2012-04-02

DATE UPDATED:

2020-05-06

SPECIES:

URI:

http://www.informatics.jax.org/searches/accession_report.cgi?id=MGI:2150766

AUTHORS:

Le Roy I, Pager J, Roubertoux PL

TITLE:

Genetic dissection of gustatory sensitivity to bitterness (sucrose octaacetate) in mice.

JOURNAL:

Comptes rendus de l\'Academie des sciences. Serie III, Sciences de la vie Oct 1999, Vol 322, pp. 831-6

ABSTRACT:

Genes implicated in consumption of a bitter compound, sucrose octaacetate (SOA), were investigated using a full genomic scanning strategy. For a 0.1 mM concentration, two QTL reached 5.8 and 6.5 lod scores on chromosomes 2 (77 cM) and 11 (14 cM), respectively. For a 1 mM concentration, the Soa linkage on chromosome 6 (58 cM, lod score 9.4) was replicated, and another QTL was found on chromosome 19 (15 cM, lod score 3.2). Candidacy of previously identified genes in the close vicinity of the peak of the QTL was examined. PUBMED: 10609087
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