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QTL associated with autoimmune epididymitis resistance 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (5706639)
QTL associated with radiation-induced apoptosis 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (31984189)
Authors:
Upton AL, Salichon N, Lebrand C, Ravary A, Blakely R, Seif I, Gaspar P
Differential gene expression in nucleus accumbens somatostatin interneurons_cocaine_mice_pvalue
Description:
To characterize transcriptional alterations that cocaine induces in these cells, we perform cell type-specific RNA-sequencing on FACS-isolated nuclei of somatostatin interneurons and identified 1100 DETs enriched for processes related to neural plasticity. To profile the entire (non poly-A selected) transcriptome of NAc somatostatin interneurons, we generated a transgenic reporter line (SST-TLG498 mice) to label the nuclei of these cells with a modified form of EGFP that is retained in the nuclear membrane (EGFP-F)22, enabling their isolation from NAc dissections using FACS. We succeeded in FACS-isolating nuclei suitable for RNA-sequencing from individual SST-TLG498 mice. We proceeded with differential expression analysis of the RNA-sequencing data to identify differentially expressed transcripts (DETs) in NAc somatostatin interneurons in response to repeated cocaine exposure: 778 transcripts were upregulated by cocaine and 322 were downregulated.
Authors:
Efrain A Ribeiro, Marine Salery, Joseph R Scarpa, Erin S Calipari, Peter J Hamilton, Stacy M Ku, Hope Kronman, Immanuel Purushothaman, Barbara Juarez, Mitra Heshmati, Marie Doyle, Casey Lardner, Dominicka Burek, Ana Strat, Stephen Pirpinias, Ezekiell Mouzon, Ming-Hu Han, Rachael L Neve, Rosemary C Bagot, Andrew Kasarskis, Ja Wook Koo, Eric J Nestler
QTL associated with Alzheimer's disease modifier 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (63242083)
Authors:
Sebastiani G, Krzywkowski P, Dudal S, Yu M, Paquette J, Malo D, Gervais F, Tremblay P
QTL associated with non-insulin-dependent diabetes mellitus 1 in NSY. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (56498226)
Authors:
Kaput J, Klein KG, Reyes EJ, Kibbe WA, Cooney CA, Jovanovic B, Visek WJ, Wolff GL
QTL associated with cytokine induced activation 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (68422759)
Authors:
Krulov M, Havelkov H, Kosarov M, Holn V, Hart AA, Demant P, Lipoldov M
QTL associated with determination of interleukin 4 commitment 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (11616475)
QTL associated with compensatory renal hypertrophy QTL 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (98544969)
QTL associated with experimental allergic encephalomyelitis susceptibility 7. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (86874328)
Authors:
Karlsson J, Zhao X, Lonskaya I, Neptin M, Holmdahl R, Andersson A
QTL associated with autoimmune orchitis resistance 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (79736435)
QTL associated with pulmonary adenoma susceptibility 5a. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (98544969)
Authors:
Wang M, Zhang Z, Zhang Z, Vikis H, Yan Y, Wang Y, You M
QTL associated with total body bone mineral density 5. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (83656096)
Authors:
Masinde GL, Li X, Gu W, Wergedal J, Mohan S, Baylink DJ
QTL for nicotine sensitivity on Chr16 at D16Mit131 (8.72 Mbp , Build 37)
Description:
nicotine sensitivity spans 0.00 - 33.72 Mbp (NCBI Build 37) on Chr16. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
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