Pathway Commons (PC) Geneset. This geneset contains genes that participate in the "IFN-gamma pathway" pathway. This set was automatically constructed using the PC API.
The original source of this geneset is pid.
gene2pc v. 0.1.0
Last updated 2015.08.31
QTL associated with C. trachomatis resistance QTL 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (57728239)
Authors:
Coers J, Bernstein-Hanley I, Grotsky D, Parvanova I, Howard JC, Taylor GA, Dietrich WF, Starnbach MN
There are discrete populations of IL-17 and IFN-γ-producing T-helper cells in psoriatic and normal dermis and peripheral blood.18 As murine Th17 cells can produce both IL-17 and IL-22,15 we wanted to investigate whether IL-17-producing cells in normal human skin and peripheral blood could also produce IL-22. We assessed expression and localization of receptors for IL-17 (IL-17R) and IL-22 (IL-22R1) on cells in normal human skin using immunohistochemical staining (n = 5).
Authors:
Nograles KE, Zaba LC, Guttman-Yassky E, Fuentes-Duculan J, Surez-Farias M, Cardinale I, Khatcherian A, Gonzalez J, Pierson KC, White TR, Pensabene C, Coats I, Novitskaya I, Lowes MA, Krueger JG
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was IFN-related cytopenia. The EFO term Chronic Hepatitis C infection was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
AJ Thompson, PJ Clark, A Singh, D Ge, J Fellay, M Zhu, Q Zhu, TJ Urban, K Patel, HL Tillmann, S Naggie, NH Afdhal, IM Jacobson, R Esteban, F Poordad, EJ Lawitz, J McCone, ML Shiffman, GW Galler, JW King, PY Kwo, KV Shianna, S Noviello, LD Pedicone, CA Brass, JK Albrecht, MS Sulkowski, DB Goldstein, JG McHutchison, AJ Muir
GWAS: Chronic Hepatitis C infection, response to interferon, depressive symptom measurement
Description:
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Depression in response to interferon-based therapy in chronic hepatitis C. The EFO term Chronic Hepatitis C infection, response to interferon, depressive symptom measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
K Matsunami, N Nishida, N Kaneko, K Ikeo, L Toyo-Oka, H Takeuchi, K Matsuura, A Tamori, H Nomura, H Yoshiji, M Imamura, N Masaki, T Hayakawa, T Ide, N Shimada, F Ikeda, K Hino, S Nishiguchi, C Okuse, S Nojiri, K Sawamoto, K Tokunaga, T Joh, Y Tanaka
GWAS: multiple sclerosis, response to interferon beta
Description:
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Response to interferon beta in multiple sclerosis. The EFO term multiple sclerosis, response to interferon beta was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
F Clarelli, G Liberatore, M Sorosina, AM Osiceanu, F Esposito, E Mascia, S Santoro, G Pavan, B Colombo, L Moiola, V Martinelli, G Comi, F Martinelli-Boneschi
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Response to interferon beta therapy. The EFO term response to interferon beta was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
F Weber, S Cepok, C Wolf, A Berthele, M Uhr, T Bettecken, D Buck, HP Hartung, F Holsboer, B Müller-Myhsok, B Hemmer
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Response to hepatitis C treatment. The EFO term Chronic Hepatitis C infection was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
H Ochi, T Maekawa, H Abe, Y Hayashida, R Nakano, M Imamura, N Hiraga, Y Kawakami, S Aimitsu, JH Kao, M Kubo, T Tsunoda, H Kumada, Y Nakamura, CN Hayes, K Chayama
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Response to hepatitis C treatment. The EFO term Chronic Hepatitis C infection was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
Y Tanaka, M Kurosaki, N Nishida, M Sugiyama, K Matsuura, N Sakamoto, N Enomoto, H Yatsuhashi, S Nishiguchi, K Hino, S Hige, Y Itoh, E Tanaka, S Mochida, M Honda, Y Hiasa, A Koike, F Sugauchi, S Kaneko, N Izumi, K Tokunaga, M Mizokami
QTL associated with "murine leukemia virus infection QTL, 1". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (151795777)
Authors:
Panoutsakopoulou V, Little CS, Sieck TG, Blankenhorn EP, Blank KJ
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Interferon alpha levels in systemic lupus erythematosus. The EFO term interferon alpha measurement, systemic lupus erythematosus was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
SN Kariuki, Y Ghodke-Puranik, JM Dorschner, BS Chrabot, JA Kelly, BP Tsao, RP Kimberly, ME Alarcón-Riquelme, CO Jacob, LA Criswell, KL Sivils, CD Langefeld, JB Harley, AD Skol, TB Niewold
QTL associated with inflammatory bowel disease QTL 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (57745571)
Authors:
Bamias G, Mishina M, Nyce M, Ross WG, Kollias G, Rivera-Nieves J, Pizarro TT, Cominelli F
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Response to hepatitis C treatment. The EFO term Chronic Hepatitis C infection was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
V Suppiah, M Moldovan, G Ahlenstiel, T Berg, M Weltman, ML Abate, M Bassendine, U Spengler, GJ Dore, E Powell, S Riordan, D Sheridan, A Smedile, V Fragomeli, T Müller, M Bahlo, GJ Stewart, DR Booth, J George
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Immune response to measles-mumps-rubella vaccine. The EFO term response to vaccine was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
RB Kennedy, IG Ovsyannikova, IH Haralambieva, ND Lambert, VS Pankratz, GA Poland
QTL associated with TNF-induced lethal shock susceptibility 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (110909916)
Authors:
Wielockx B, Staelens J, Puimge L, Vanlaere I, Van Roy M, van Lint P, Van Roy F, Libert C
QTL associated with TNF-induced lethal shock susceptibility 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (84734943)
Authors:
Wielockx B, Staelens J, Puimge L, Vanlaere I, Van Roy M, van Lint P, Van Roy F, Libert C
significantly different proteins from severe patients
Description:
People with severe cases of Covid-19 express these proteins at significantly higher levels than people with mild cases of Covid-19. Data from Figure 2 of the paper: plasma cytokine levels in patients with Covid-19.
Authors:
Guang Chen, Di Wu, Wei Guo, Yong Cao, Da Huang, Hongwu Wang, Tao Wang, Xiaoyun Zhang, Huilong Chen, Haijing Yu, Xiaoping Zhang, Minxia Zhang, Shiji Wu, Jianxin Song, Tao Chen, Meifang Han, Shusheng Li, Xiaoping Luo, Jianping Zhao, Qin Ning
Study aimed to identify specific gene signatures in peripheral blood cells (PBCs) of Behcet's disease patients with active disease using novel gene expression and network analysis. 179 genes were modulated in 10 PBCs of BD patients when compared to 10 healthy donors.
Authors:
Antonio Puccetti, Piera Filomena Fiore, Andrea Pelosi, Elisa Tinazzi, Giuseppe Patuzzo, Giuseppe Argentino, Francesca Moretta, Claudio Lunardi, Marzia Dolcino
The production of 12 out of 27 measured factors was induced by CEsHUT including IL-1β, TNF and IL-1Ra. In contrast to sIL-1Ra production, that of IL-1β and TNF was inhibited by HDL, corroborating previous results. In addition, CEsHUT induced monocytes to produce factors involved in their localization, survival and differentiation such as CCL5 (RANTES), CCL2 (MCP-1), interferon-γ (IFNγ), granulocyte-macrophage colony-stimulating factor (GM-CSF), and macrophage-CSF (M-CSF). The production of the latter was moderate and it was not affected by HDL.
Authors:
Gruaz L, Delucinge-Vivier C, Descombes P, Dayer JM, Burger D
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