Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "BORC complex", which is defined as "A protein complex that is invovled in positioning of the lysosome within the cytoplasm and which is composed of BLOC1S1, BLOC1S2, BORCS5, BORCS6, BORCS7, BORCS8, KXD1 and SNAPIN. The BORC complex recruits ARL8 at the cytosolic face of lysosomes and couples them to microtubule plus-end-directed kinesin motors." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Schizophrenia. The EFO term schizophrenia was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
S Ripke, C O'Dushlaine, K Chambert, JL Moran, AK Kähler, S Akterin, SE Bergen, AL Collins, JJ Crowley, M Fromer, Y Kim, SH Lee, PK Magnusson, N Sanchez, EA Stahl, S Williams, NR Wray, K Xia, F Bettella, AD Borglum, BK Bulik-Sullivan, P Cormican, N Craddock, C de Leeuw, N Durmishi, M Gill, V Golimbet, ML Hamshere, P Holmans, DM Hougaard, KS Kendler, K Lin, DW Morris, O Mors, PB Mortensen, BM Neale, FA O'Neill, MJ Owen, MP Milovancevic, D Posthuma, J Powell, AL Richards, BP Riley, D Ruderfer, D Rujescu, E Sigurdsson, T Silagadze, AB Smit, H Stefansson, S Steinberg, J Suvisaari, S Tosato, M Verhage, JT Walters, DF Levinson, PV Gejman, KS Kendler, C Laurent, BJ Mowry, MC O'Donovan, MJ Owen, AE Pulver, BP Riley, SG Schwab, DB Wildenauer, F Dudbridge, P Holmans, J Shi, M Albus, M Alexander, D Campion, D Cohen, D Dikeos, J Duan, P Eichhammer, S Godard, M Hansen, FB Lerer, KY Liang, W Maier, J Mallet, DA Nertney, G Nestadt, N Norton, FA O'Neill, GN Papadimitriou, R Ribble, AR Sanders, JM Silverman, D Walsh, NM Williams, B Wormley, MJ Arranz, S Bakker, S Bender, E Bramon, D Collier, B Crespo-Facorro, J Hall, C Iyegbe, A Jablensky, RS Kahn, L Kalaydjieva, S Lawrie, CM Lewis, K Lin, DH Linszen, I Mata, A McIntosh, RM Murray, RA Ophoff, J Powell, D Rujescu, J Van Os, M Walshe, M Weisbrod, D Wiersma, P Donnelly, I Barroso, JM Blackwell, E Bramon, MA Brown, JP Casas, AP Corvin, P Deloukas, A Duncanson, J Jankowski, HS Markus, CG Mathew, CN Palmer, R Plomin, A Rautanen, SJ Sawcer, RC Trembath, AC Viswanathan, NW Wood, CC Spencer, G Band, C Bellenguez, C Freeman, G Hellenthal, E Giannoulatou, M Pirinen, RD Pearson, A Strange, Z Su, D Vukcevic, P Donnelly, C Langford, SE Hunt, S Edkins, R Gwilliam, H Blackburn, SJ Bumpstead, S Dronov, M Gillman, E Gray, N Hammond, A Jayakumar, OT McCann, J Liddle, SC Potter, R Ravindrarajah, M Ricketts, A Tashakkori-Ghanbaria, MJ Waller, P Weston, S Widaa, P Whittaker, I Barroso, P Deloukas, CG Mathew, JM Blackwell, MA Brown, AP Corvin, MI McCarthy, CC Spencer, E Bramon, AP Corvin, MC O'Donovan, K Stefansson, E Scolnick, S Purcell, SA McCarroll, P Sklar, CM Hultman, PF Sullivan
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Arsenic metabolism. The EFO term urinary arsenic measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
BL Pierce, MG Kibriya, L Tong, F Jasmine, M Argos, S Roy, R Paul-Brutus, R Rahaman, M Rakibuz-Zaman, F Parvez, A Ahmed, I Quasem, SK Hore, S Alam, T Islam, V Slavkovich, MV Gamble, M Yunus, M Rahman, JA Baron, JH Graziano, H Ahsan
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Microalbuminuria. The EFO term Microalbuminuria was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
A Teumer, A Tin, R Sorice, M Gorski, NC Yeo, AY Chu, M Li, Y Li, V Mijatovic, YA Ko, D Taliun, A Luciani, MH Chen, Q Yang, MC Foster, M Olden, LT Hiraki, BO Tayo, C Fuchsberger, AK Dieffenbach, AR Shuldiner, AV Smith, AM Zappa, A Lupo, B Kollerits, B Ponte, B Stengel, BK Krämer, B Paulweber, BD Mitchell, C Hayward, C Helmer, C Meisinger, C Gieger, CM Shaffer, C Müller, C Langenberg, D Ackermann, D Siscovick, E Boerwinkle, F Kronenberg, GB Ehret, G Homuth, G Waeber, G Navis, G Gambaro, G Malerba, G Eiriksdottir, G Li, HE Wichmann, H Grallert, H Wallaschofski, H Völzke, H Brenner, H Kramer, I Mateo Leach, I Rudan, HL Hillege, JS Beckmann, JC Lambert, J Luan, JH Zhao, J Chalmers, J Coresh, JC Denny, K Butterbach, LJ Launer, L Ferrucci, L Kedenko, M Haun, M Metzger, M Woodward, MJ Hoffman, M Nauck, M Waldenberger, M Pruijm, M Bochud, M Rheinberger, N Verweij, NJ Wareham, N Endlich, N Soranzo, O Polasek, P van der Harst, PP Pramstaller, P Vollenweider, PS Wild, RT Gansevoort, R Rettig, R Biffar, RJ Carroll, R Katz, RJ Loos, SJ Hwang, S Coassin, S Bergmann, SE Rosas, S Stracke, TB Harris, T Corre, T Zeller, T Illig, T Aspelund, T Tanaka, U Lendeckel, U Völker, V Gudnason, V Chouraki, W Koenig, Z Kutalik, JR O'Connell, A Parsa, IM Heid, AD Paterson, IH de Boer, O Devuyst, J Lazar, K Endlich, K Susztak, J Tremblay, P Hamet, HJ Jacob, CA Böger, CS Fox, C Pattaro, A Köttgen
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Systolic blood pressure. The EFO term systolic blood pressure was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
X Lu, L Wang, X Lin, J Huang, C Charles Gu, M He, H Shen, J He, J Zhu, H Li, JE Hixson, T Wu, J Dai, L Lu, C Shen, S Chen, L He, Z Mo, Y Hao, X Mo, X Yang, J Li, J Cao, J Chen, Z Fan, Y Li, L Zhao, H Li, F Lu, C Yao, L Yu, L Xu, J Mu, X Wu, Y Deng, D Hu, W Zhang, X Ji, D Guo, Z Guo, Z Zhou, Z Yang, R Wang, J Yang, X Zhou, W Yan, N Sun, P Gao, D Gu
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Hypertension. The EFO term hypertension was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
X Lu, L Wang, X Lin, J Huang, C Charles Gu, M He, H Shen, J He, J Zhu, H Li, JE Hixson, T Wu, J Dai, L Lu, C Shen, S Chen, L He, Z Mo, Y Hao, X Mo, X Yang, J Li, J Cao, J Chen, Z Fan, Y Li, L Zhao, H Li, F Lu, C Yao, L Yu, L Xu, J Mu, X Wu, Y Deng, D Hu, W Zhang, X Ji, D Guo, Z Guo, Z Zhou, Z Yang, R Wang, J Yang, X Zhou, W Yan, N Sun, P Gao, D Gu
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Diastolic blood pressure. The EFO term diastolic blood pressure was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
X Lu, L Wang, X Lin, J Huang, C Charles Gu, M He, H Shen, J He, J Zhu, H Li, JE Hixson, T Wu, J Dai, L Lu, C Shen, S Chen, L He, Z Mo, Y Hao, X Mo, X Yang, J Li, J Cao, J Chen, Z Fan, Y Li, L Zhao, H Li, F Lu, C Yao, L Yu, L Xu, J Mu, X Wu, Y Deng, D Hu, W Zhang, X Ji, D Guo, Z Guo, Z Zhou, Z Yang, R Wang, J Yang, X Zhou, W Yan, N Sun, P Gao, D Gu
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Prostate cancer. The EFO term prostate carcinoma was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
RA Eeles, AA Olama, S Benlloch, EJ Saunders, DA Leongamornlert, M Tymrakiewicz, M Ghoussaini, C Luccarini, J Dennis, S Jugurnauth-Little, T Dadaev, DE Neal, FC Hamdy, JL Donovan, K Muir, GG Giles, G Severi, F Wiklund, H Gronberg, CA Haiman, F Schumacher, BE Henderson, L Le Marchand, S Lindstrom, P Kraft, DJ Hunter, S Gapstur, SJ Chanock, SI Berndt, D Albanes, G Andriole, J Schleutker, M Weischer, F Canzian, E Riboli, TJ Key, RC Travis, D Campa, SA Ingles, EM John, RB Hayes, PD Pharoah, N Pashayan, KT Khaw, JL Stanford, EA Ostrander, LB Signorello, SN Thibodeau, D Schaid, C Maier, W Vogel, AS Kibel, C Cybulski, J Lubinski, L Cannon-Albright, H Brenner, JY Park, R Kaneva, J Batra, AB Spurdle, JA Clements, MR Teixeira, E Dicks, A Lee, AM Dunning, C Baynes, D Conroy, MJ Maranian, S Ahmed, K Govindasami, M Guy, RA Wilkinson, EJ Sawyer, A Morgan, DP Dearnaley, A Horwich, RA Huddart, VS Khoo, CC Parker, NJ Van As, CJ Woodhouse, A Thompson, T Dudderidge, C Ogden, CS Cooper, A Lophatananon, A Cox, MC Southey, JL Hopper, DR English, M Aly, J Adolfsson, J Xu, SL Zheng, M Yeager, R Kaaks, WR Diver, MM Gaudet, MC Stern, R Corral, AD Joshi, A Shahabi, T Wahlfors, TL Tammela, A Auvinen, J Virtamo, P Klarskov, BG Nordestgaard, MA Røder, SF Nielsen, SE Bojesen, A Siddiq, LM Fitzgerald, S Kolb, EM Kwon, DM Karyadi, WJ Blot, W Zheng, Q Cai, SK McDonnell, AE Rinckleb, B Drake, G Colditz, D Wokolorczyk, RA Stephenson, C Teerlink, H Muller, D Rothenbacher, TA Sellers, HY Lin, C Slavov, V Mitev, F Lose, S Srinivasan, S Maia, P Paulo, E Lange, KA Cooney, AC Antoniou, D Vincent, F Bacot, DC Tessier, Z Kote-Jarai, DF Easton
Data from GEO GSE194368 and analyzed using GEO2R, only top gene shown. Authors identified transcriptional adaptations of GR signaling in the amygdala of humans with OUD. Thus, GRs, their coregulators and downstream systems may represent viable therapeutic targets to treat the “stress side” of OUD.
Authors:
Stephanie A Carmack, Janaina C M Vendruscolo, M Adrienne McGinn, Jorge Miranda-Barrientos, Vez Repunte-Canonigo, Gabriel D Bosse, Daniele Mercatelli, Federico M Giorgi, Yu Fu, Anthony J Hinrich, Francine M Jodelka, Karen Ling, Robert O Messing, Randall T Peterson, Frank Rigo, Scott Edwards, Pietro P Sanna, Marisela Morales, Michelle L Hastings, George F Koob, Leandro F Vendruscolo
Hippocampus Gene Expression Correlates for C1HCOUNT30 measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C1HCOUNT30 measures Open Field locomotion 15-30 min post cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C1HCOUNT45 measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C1HCOUNT45 measures Open Field locomotion 30-45 min post cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C2HCOUNT30 measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C2HCOUNT30 measures Open Field locomotion (activity beam breaks) 15-30 min post 2nd cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C2HCOUNT45 measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C2HCOUNT45 measures Open Field locomotion (activity beam breaks) 30-45 min post 2nd cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C2HDIS30 measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C2HDIS30 measures Open Field locomotion (cm) 15-30 min post 2nd cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C2HDIS45 measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C2HDIS45 measures Open Field locomotion (cm) 30-45 min post 2nd cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for LOC_CHCL_ACOUNT_3 measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The LOC_CHCL_ACOUNT_3 measures Cocaine TOTAL locomotion (activity beam breaks) under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for LOC_CHCL_ADIST_3 measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The LOC_CHCL_ADIST_3 measures Cocaine TOTAL locomotion ( cm in 1 hr) under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for SEN_CHCL_ACOUNT_4 measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The SEN_CHCL_ACOUNT_4 measures Cocaine Sensitization - TOTAL locomotion (activity beam breaks) under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for SEN_CHCL_ADIST_4 measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The SEN_CHCL_ADIST_4 measures Cocaine Sensitization - TOTAL locomotion ( cm in 1 hr) under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for COCA_TEST_VEHICLE measured in BXD RI Females obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The COCA_TEST_VEHICLE measures Cocaine CPP - Time (s) in saline paired compartment a under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Renthal W, Kumar A, Xiao G, Wilkinson M, Covington HE 3rd, Maze I, Sikder D, Robison AJ, LaPlant Q, Dietz DM, Russo SJ, Vialou V, Chakravarty S, Kodadek TJ, Stack A, Kabbaj M, Nestler EJ
Renthal W, Kumar A, Xiao G, Wilkinson M, Covington HE 3rd, Maze I, Sikder D, Robison AJ, LaPlant Q, Dietz DM, Russo SJ, Vialou V, Chakravarty S, Kodadek TJ, Stack A, Kabbaj M, Nestler EJ
QTL for METH responses for body temperature on Chr19 at Lpc1 (23.27 Mbp , Build 37)
Description:
METH responses for body temperature spans 0.00 - 48.27 Mbp (NCBI Build 37) on Chr19. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for alcohol preference locus on Chr19 at D19Mit46 (29.54 Mbp , Build 37)
Description:
alcohol preference locus spans 4.54 - 54.54 Mbp (NCBI Build 37) on Chr19. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for alcohol preference locus on Chr19 at D19Mit46 (29.54 Mbp , Build 37)
Description:
alcohol preference locus spans 4.54 - 54.54 Mbp (NCBI Build 37) on Chr19. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
GeneWeaver