List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Age-related macular degeneration. The EFO term age-related macular degeneration was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
Y Yu, TR Bhangale, J Fagerness, S Ripke, G Thorleifsson, PL Tan, EH Souied, AJ Richardson, JE Merriam, GH Buitendijk, R Reynolds, S Raychaudhuri, KA Chin, L Sobrin, E Evangelou, PH Lee, AY Lee, N Leveziel, DJ Zack, B Campochiaro, P Campochiaro, RT Smith, GR Barile, RH Guymer, R Hogg, U Chakravarthy, LD Robman, O Gustafsson, H Sigurdsson, W Ortmann, TW Behrens, K Stefansson, AG Uitterlinden, CM van Duijn, JR Vingerling, CC Klaver, R Allikmets, MA Brantley, PN Baird, N Katsanis, U Thorsteinsdottir, JP Ioannidis, MJ Daly, RR Graham, JM Seddon
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Waist-hip ratio. The EFO term waist-hip ratio was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Thyroid hormone levels. The EFO term thyroid stimulating hormone measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
E Porcu, M Medici, G Pistis, CB Volpato, SG Wilson, AR Cappola, SD Bos, J Deelen, M den Heijer, RM Freathy, J Lahti, C Liu, LM Lopez, IM Nolte, JR O'Connell, T Tanaka, S Trompet, A Arnold, S Bandinelli, M Beekman, S Böhringer, SJ Brown, BM Buckley, C Camaschella, AJ de Craen, G Davies, MC de Visser, I Ford, T Forsen, TM Frayling, L Fugazzola, M Gögele, AT Hattersley, AR Hermus, A Hofman, JJ Houwing-Duistermaat, RA Jensen, E Kajantie, M Kloppenburg, EM Lim, C Masciullo, S Mariotti, C Minelli, BD Mitchell, R Nagaraja, RT Netea-Maier, A Palotie, L Persani, MG Piras, BM Psaty, K Räikkönen, JB Richards, F Rivadeneira, C Sala, MM Sabra, N Sattar, BM Shields, N Soranzo, JM Starr, DJ Stott, FC Sweep, G Usala, MM van der Klauw, D van Heemst, A van Mullem, SH Vermeulen, WE Visser, JP Walsh, RG Westendorp, E Widen, G Zhai, F Cucca, IJ Deary, JG Eriksson, L Ferrucci, CS Fox, JW Jukema, LA Kiemeney, PP Pramstaller, D Schlessinger, AR Shuldiner, EP Slagboom, AG Uitterlinden, B Vaidya, TJ Visser, BH Wolffenbuttel, I Meulenbelt, JI Rotter, TD Spector, AA Hicks, D Toniolo, S Sanna, RP Peeters, S Naitza
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Urate levels. The EFO term urate measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
A Köttgen, E Albrecht, A Teumer, V Vitart, J Krumsiek, C Hundertmark, G Pistis, D Ruggiero, CM O'Seaghdha, T Haller, Q Yang, T Tanaka, AD Johnson, Z Kutalik, AV Smith, J Shi, M Struchalin, RP Middelberg, MJ Brown, AL Gaffo, N Pirastu, G Li, C Hayward, T Zemunik, J Huffman, L Yengo, JH Zhao, A Demirkan, MF Feitosa, X Liu, G Malerba, LM Lopez, P van der Harst, X Li, ME Kleber, AA Hicks, IM Nolte, A Johansson, F Murgia, SH Wild, SJ Bakker, JF Peden, A Dehghan, M Steri, A Tenesa, V Lagou, P Salo, M Mangino, LM Rose, T Lehtimäki, OM Woodward, Y Okada, A Tin, C Müller, C Oldmeadow, M Putku, D Czamara, P Kraft, L Frogheri, GA Thun, A Grotevendt, GK Gislason, TB Harris, LJ Launer, P McArdle, AR Shuldiner, E Boerwinkle, J Coresh, H Schmidt, M Schallert, NG Martin, GW Montgomery, M Kubo, Y Nakamura, T Tanaka, PB Munroe, NJ Samani, DR Jacobs, K Liu, P D'Adamo, S Ulivi, JI Rotter, BM Psaty, P Vollenweider, G Waeber, S Campbell, O Devuyst, P Navarro, I Kolcic, N Hastie, B Balkau, P Froguel, T Esko, A Salumets, KT Khaw, C Langenberg, NJ Wareham, A Isaacs, A Kraja, Q Zhang, PS Wild, RJ Scott, EG Holliday, E Org, M Viigimaa, S Bandinelli, JE Metter, A Lupo, E Trabetti, R Sorice, A Döring, E Lattka, K Strauch, F Theis, M Waldenberger, HE Wichmann, G Davies, AJ Gow, M Bruinenberg, RP Stolk, JS Kooner, W Zhang, BR Winkelmann, BO Boehm, S Lucae, BW Penninx, JH Smit, G Curhan, P Mudgal, RM Plenge, L Portas, I Persico, M Kirin, JF Wilson, I Mateo Leach, WH van Gilst, A Goel, H Ongen, A Hofman, F Rivadeneira, AG Uitterlinden, M Imboden, A von Eckardstein, F Cucca, R Nagaraja, MG Piras, M Nauck, C Schurmann, K Budde, F Ernst, SM Farrington, E Theodoratou, I Prokopenko, M Stumvoll, A Jula, M Perola, V Salomaa, SY Shin, TD Spector, C Sala, PM Ridker, M Kähönen, J Viikari, C Hengstenberg, CP Nelson, JF Meschia, MA Nalls, P Sharma, AB Singleton, N Kamatani, T Zeller, M Burnier, J Attia, M Laan, N Klopp, HL Hillege, S Kloiber, H Choi, M Pirastu, S Tore, NM Probst-Hensch, H Völzke, V Gudnason, A Parsa, R Schmidt, JB Whitfield, M Fornage, P Gasparini, DS Siscovick, O Polašek, H Campbell, I Rudan, N Bouatia-Naji, A Metspalu, RJ Loos, CM van Duijn, IB Borecki, L Ferrucci, G Gambaro, IJ Deary, BH Wolffenbuttel, JC Chambers, W März, PP Pramstaller, H Snieder, U Gyllensten, AF Wright, G Navis, H Watkins, JC Witteman, S Sanna, S Schipf, MG Dunlop, A Tönjes, S Ripatti, N Soranzo, D Toniolo, DI Chasman, O Raitakari, WH Kao, M Ciullo, CS Fox, M Caulfield, M Bochud, C Gieger
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Vascular endothelial growth factor levels. The EFO term vascular endothelial growth factor measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
SH Choi, D Ruggiero, R Sorice, C Song, T Nutile, A Vernon Smith, MP Concas, M Traglia, C Barbieri, NC Ndiaye, MG Stathopoulou, V Lagou, GB Maestrale, C Sala, S Debette, P Kovacs, L Lind, J Lamont, P Fitzgerald, A Tönjes, V Gudnason, D Toniolo, M Pirastu, C Bellenguez, RS Vasan, E Ingelsson, AL Leutenegger, AD Johnson, AL DeStefano, S Visvikis-Siest, S Seshadri, M Ciullo
GWAS: anthropometric measurement, waist-hip ratio, sexual dimorphism
Description:
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Sexual dimorphism in anthropometric traits. The EFO term anthropometric measurement, waist-hip ratio, sexual dimorphism was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JC Randall, TW Winkler, Z Kutalik, SI Berndt, AU Jackson, KL Monda, TO Kilpeläinen, T Esko, R Mägi, S Li, T Workalemahu, MF Feitosa, DC Croteau-Chonka, FR Day, T Fall, T Ferreira, S Gustafsson, AE Locke, I Mathieson, A Scherag, S Vedantam, AR Wood, L Liang, V Steinthorsdottir, G Thorleifsson, ET Dermitzakis, AS Dimas, F Karpe, JL Min, G Nicholson, DJ Clegg, T Person, JP Krohn, S Bauer, C Buechler, K Eisinger, A Bonnefond, P Froguel, JJ Hottenga, I Prokopenko, LL Waite, TB Harris, AV Smith, AR Shuldiner, WL McArdle, MJ Caulfield, PB Munroe, H Grönberg, YD Chen, G Li, JS Beckmann, T Johnson, U Thorsteinsdottir, M Teder-Laving, KT Khaw, NJ Wareham, JH Zhao, N Amin, BA Oostra, AT Kraja, MA Province, LA Cupples, NL Heard-Costa, J Kaprio, S Ripatti, I Surakka, FS Collins, J Saramies, J Tuomilehto, A Jula, V Salomaa, J Erdmann, C Hengstenberg, C Loley, H Schunkert, C Lamina, HE Wichmann, E Albrecht, C Gieger, AA Hicks, A Johansson, PP Pramstaller, S Kathiresan, EK Speliotes, B Penninx, AL Hartikainen, MR Jarvelin, U Gyllensten, DI Boomsma, H Campbell, JF Wilson, SJ Chanock, M Farrall, A Goel, C Medina-Gomez, F Rivadeneira, K Estrada, AG Uitterlinden, A Hofman, MC Zillikens, M den Heijer, LA Kiemeney, A Maschio, P Hall, J Tyrer, A Teumer, H Völzke, P Kovacs, A Tönjes, M Mangino, TD Spector, C Hayward, I Rudan, AS Hall, NJ Samani, AP Attwood, JG Sambrook, J Hung, LJ Palmer, ML Lokki, J Sinisalo, G Boucher, H Huikuri, M Lorentzon, C Ohlsson, N Eklund, JG Eriksson, C Barlassina, C Rivolta, IM Nolte, H Snieder, MM Van der Klauw, JV Van Vliet-Ostaptchouk, PV Gejman, J Shi, KB Jacobs, Z Wang, SJ Bakker, I Mateo Leach, G Navis, P van der Harst, NG Martin, SE Medland, GW Montgomery, J Yang, DI Chasman, PM Ridker, LM Rose, T Lehtimäki, O Raitakari, D Absher, C Iribarren, H Basart, KG Hovingh, E Hyppönen, C Power, D Anderson, JP Beilby, J Hui, J Jolley, H Sager, SR Bornstein, PE Schwarz, K Kristiansson, M Perola, J Lindström, AJ Swift, M Uusitupa, M Atalay, TA Lakka, R Rauramaa, JL Bolton, G Fowkes, RM Fraser, JF Price, K Fischer, K Krjutå Kov, A Metspalu, E Mihailov, C Langenberg, J Luan, KK Ong, PS Chines, SM Keinanen-Kiukaanniemi, TE Saaristo, S Edkins, PW Franks, G Hallmans, D Shungin, AD Morris, CN Palmer, R Erbel, S Moebus, MM Nöthen, S Pechlivanis, K Hveem, N Narisu, A Hamsten, SE Humphries, RJ Strawbridge, E Tremoli, H Grallert, B Thorand, T Illig, W Koenig, M Müller-Nurasyid, A Peters, BO Boehm, ME Kleber, W März, BR Winkelmann, J Kuusisto, M Laakso, D Arveiler, G Cesana, K Kuulasmaa, J Virtamo, JW Yarnell, D Kuh, A Wong, L Lind, U de Faire, B Gigante, PK Magnusson, NL Pedersen, G Dedoussis, M Dimitriou, G Kolovou, S Kanoni, K Stirrups, LL Bonnycastle, I Njølstad, T Wilsgaard, A Ganna, E Rehnberg, A Hingorani, M Kivimaki, M Kumari, TL Assimes, I Barroso, M Boehnke, IB Borecki, P Deloukas, CS Fox, T Frayling, LC Groop, T Haritunians, D Hunter, E Ingelsson, R Kaplan, KL Mohlke, JR O'Connell, D Schlessinger, DP Strachan, K Stefansson, CM van Duijn, GR Abecasis, MI McCarthy, JN Hirschhorn, L Qi, RJ Loos, CM Lindgren, KE North, IM Heid
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Chronic kidney disease. The EFO term chronic kidney disease, serum creatinine measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Serum VEGFR2 concentration. The EFO term serum VEGFR2 concentration measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
ML Maitland, CF Xu, YC Cheng, E Kistner-Griffin, KA Ryan, TG Karrison, S Das, D Torgerson, ER Gamazon, V Thomeas, MR Levine, PA Wilson, N Bing, Y Liu, LR Cardon, LN Pandite, JR O'Connell, NJ Cox, BD Mitchell, MJ Ratain, AR Shuldiner
Gene expression changes in the post-mortem nucleus accumbens of chronic heroin abusers. Overall, little overlap in gene expression profiles was seen between the two drug-abusing cohorts: out of the approximately 39,000 transcripts investigated, the abundance of only 25 was significantly changed in both cocaine and heroin abusers, with nearly one-half of these being altered in opposite directions. 1050 Transcripts had different in abundance between the majority of heroin subjects and their matched controls.
Hippocampus Gene Expression Correlates for C1VCOUNT15 measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C1VCOUNT15 measures Open Field rears 0-15 min post cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C1VCOUNT30 measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C1VCOUNT30 measures Open Field rears 15-30 min post cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C2VCOUNT45 measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C2VCOUNT45 measures Open Field rears 30-45 min post 2nd cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for NEINVCOUNT30 measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The NEINVCOUNT30 measures Novel environment rears 15-30 min in the center under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for SEN_CHCL_VCOUNT_4 measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The SEN_CHCL_VCOUNT_4 measures Cocaine Sensitization - TOTAL rears under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
QTL for ethanol conditioned taste aversion on Chr17 at D17Ncvs39 (23.83 Mbp , Build 37)
Description:
ethanol conditioned taste aversion spans 0.00 - 48.83 Mbp (NCBI Build 37) on Chr17. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for differences in cocaine responsiveness on Chr17 at Ck-2 (45.25 Mbp , Build 37)
Description:
differences in cocaine responsiveness spans 20.25 - 70.25 Mbp (NCBI Build 37) on Chr17. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for differences in cocaine responsiveness on Chr17 at D17MIt7 (51.99 Mbp , Build 37)
Description:
differences in cocaine responsiveness spans 26.99 - 76.99 Mbp (NCBI Build 37) on Chr17. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for t-psl on Chr17 at Hp (53.97 Mbp , Build 37)
Description:
t-psl spans 28.97 - 78.97 Mbp (NCBI Build 37) on Chr17. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for differences in cocaine responsiveness on Chr17 at DI7Mft3 (64.20 Mbp , Build 37)
Description:
differences in cocaine responsiveness spans 39.20 - 89.20 Mbp (NCBI Build 37) on Chr17. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for home cage activity on Chr17 at D17Mit3 (70.84 Mbp , Build 37)
Description:
METH responses for home cage activity spans 45.84 - 95.84 Mbp (NCBI Build 37) on Chr17. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
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