QTL spans- 118.3-168.3 Mbp (NCBI Build 37) on Chr3. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org). Ethanol consumption in mice was analyzed in selectively breed mice derived from an F2 population of intercrossed (C57BL/6J x DBA/2J)F1 mice. Whereas C57BL/6J are high consumers of alcohol and DBA/2J are low consumers. The concentration of ethanol used was 10%. With low preference mice and high preference mice mated for a maximum of 4 generations. In generation 4 of the Low selected line a significant QTL was observed and associated with D3Mit17. Authors suggest Adh1 may be a candidate gene.
Ethanol Induced Hypothermia Chr# 3 rs3710548 (145932289) with right flanking marker rs3719390 (85222358) and left marker rs30801216 (156802752). This was mapped in 300 + (b6x129)F2 mice.
QTL associated with activity response to ethanol 5. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (147806689)
Authors:
Malmanger B, Lawler M, Coulombe S, Murray R, Cooper S, Polyakov Y, Belknap J, Hitzemann R
QTL associated with "alcohol preference locus 3, male specific". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (147694263)
QTL associated with atherosclerotic lesion area 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (147806703)
QTL associated with bone response to mechanical loading 4. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (143227451)
QTL associated with circulating hormone level QTL 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (142848413)
Authors:
Harper JM, Galecki AT, Burke DT, Pinkosky SL, Miller RA
QTL associated with experimental allergic encephalomyelitis susceptibility10. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (143310189)
QTL associated with epistatic bone marrow graft rejection 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (156321292)
Authors:
Johansson MH, Taylor MA, Jagodic M, Tus K, Schatzle JD, Wakeland EK, Bennett M
QTL associated with ethanol induced loss of righting response 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (142848413)
QTL associated with hepatic lipase activity in BSB 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (147407716)
QTL associated with lymphoproliferation modifier 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (136736060)
Authors:
Qu WM, Miyazaki T, Terada M, Lu LM, Nishihara M, Yamada A, Mori S, Nakamura Y, Ogasawara H, Yazawa C, Nakatsuru S, Nose M
QTL associated with novelty/stress induced locomotor activation 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (131569282)
QTL associated with periosteal circumference 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (143227451)
Authors:
Kesavan C, Mohan S, Srivastava AK, Kapoor S, Wergedal JE, Yu H, Baylink DJ
QTL associated with colon tumor susceptibility 7. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (147407716)
Authors:
van Wezel T, Ruivenkamp CA, Stassen AP, Moen CJ, Demant P
QTL associated with salmonella enteritidis susceptibility 9. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (136014535)
Differential gene expression of RNA-Seq data for alcohol dependence. Gene Symbol and p-value (unadjusted). Samples were from twenty-three hippocampi from eight people with a history of alcohol user, seven people with a history of cocaine uses, and eight matched control subjects.
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