GWAS: anthropometric measurement, waist-hip ratio, sexual dimorphism
Description:
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Sexual dimorphism in anthropometric traits. The EFO term anthropometric measurement, waist-hip ratio, sexual dimorphism was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JC Randall, TW Winkler, Z Kutalik, SI Berndt, AU Jackson, KL Monda, TO Kilpeläinen, T Esko, R Mägi, S Li, T Workalemahu, MF Feitosa, DC Croteau-Chonka, FR Day, T Fall, T Ferreira, S Gustafsson, AE Locke, I Mathieson, A Scherag, S Vedantam, AR Wood, L Liang, V Steinthorsdottir, G Thorleifsson, ET Dermitzakis, AS Dimas, F Karpe, JL Min, G Nicholson, DJ Clegg, T Person, JP Krohn, S Bauer, C Buechler, K Eisinger, A Bonnefond, P Froguel, JJ Hottenga, I Prokopenko, LL Waite, TB Harris, AV Smith, AR Shuldiner, WL McArdle, MJ Caulfield, PB Munroe, H Grönberg, YD Chen, G Li, JS Beckmann, T Johnson, U Thorsteinsdottir, M Teder-Laving, KT Khaw, NJ Wareham, JH Zhao, N Amin, BA Oostra, AT Kraja, MA Province, LA Cupples, NL Heard-Costa, J Kaprio, S Ripatti, I Surakka, FS Collins, J Saramies, J Tuomilehto, A Jula, V Salomaa, J Erdmann, C Hengstenberg, C Loley, H Schunkert, C Lamina, HE Wichmann, E Albrecht, C Gieger, AA Hicks, A Johansson, PP Pramstaller, S Kathiresan, EK Speliotes, B Penninx, AL Hartikainen, MR Jarvelin, U Gyllensten, DI Boomsma, H Campbell, JF Wilson, SJ Chanock, M Farrall, A Goel, C Medina-Gomez, F Rivadeneira, K Estrada, AG Uitterlinden, A Hofman, MC Zillikens, M den Heijer, LA Kiemeney, A Maschio, P Hall, J Tyrer, A Teumer, H Völzke, P Kovacs, A Tönjes, M Mangino, TD Spector, C Hayward, I Rudan, AS Hall, NJ Samani, AP Attwood, JG Sambrook, J Hung, LJ Palmer, ML Lokki, J Sinisalo, G Boucher, H Huikuri, M Lorentzon, C Ohlsson, N Eklund, JG Eriksson, C Barlassina, C Rivolta, IM Nolte, H Snieder, MM Van der Klauw, JV Van Vliet-Ostaptchouk, PV Gejman, J Shi, KB Jacobs, Z Wang, SJ Bakker, I Mateo Leach, G Navis, P van der Harst, NG Martin, SE Medland, GW Montgomery, J Yang, DI Chasman, PM Ridker, LM Rose, T Lehtimäki, O Raitakari, D Absher, C Iribarren, H Basart, KG Hovingh, E Hyppönen, C Power, D Anderson, JP Beilby, J Hui, J Jolley, H Sager, SR Bornstein, PE Schwarz, K Kristiansson, M Perola, J Lindström, AJ Swift, M Uusitupa, M Atalay, TA Lakka, R Rauramaa, JL Bolton, G Fowkes, RM Fraser, JF Price, K Fischer, K Krjutå Kov, A Metspalu, E Mihailov, C Langenberg, J Luan, KK Ong, PS Chines, SM Keinanen-Kiukaanniemi, TE Saaristo, S Edkins, PW Franks, G Hallmans, D Shungin, AD Morris, CN Palmer, R Erbel, S Moebus, MM Nöthen, S Pechlivanis, K Hveem, N Narisu, A Hamsten, SE Humphries, RJ Strawbridge, E Tremoli, H Grallert, B Thorand, T Illig, W Koenig, M Müller-Nurasyid, A Peters, BO Boehm, ME Kleber, W März, BR Winkelmann, J Kuusisto, M Laakso, D Arveiler, G Cesana, K Kuulasmaa, J Virtamo, JW Yarnell, D Kuh, A Wong, L Lind, U de Faire, B Gigante, PK Magnusson, NL Pedersen, G Dedoussis, M Dimitriou, G Kolovou, S Kanoni, K Stirrups, LL Bonnycastle, I Njølstad, T Wilsgaard, A Ganna, E Rehnberg, A Hingorani, M Kivimaki, M Kumari, TL Assimes, I Barroso, M Boehnke, IB Borecki, P Deloukas, CS Fox, T Frayling, LC Groop, T Haritunians, D Hunter, E Ingelsson, R Kaplan, KL Mohlke, JR O'Connell, D Schlessinger, DP Strachan, K Stefansson, CM van Duijn, GR Abecasis, MI McCarthy, JN Hirschhorn, L Qi, RJ Loos, CM Lindgren, KE North, IM Heid
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Myopia (pathological). The EFO term pathological myopia was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
Q Fan, VA Barathi, CY Cheng, X Zhou, A Meguro, I Nakata, CC Khor, LK Goh, YJ Li, W Lim, CE Ho, F Hawthorne, Y Zheng, D Chua, H Inoko, K Yamashiro, K Ohno-Matsui, K Matsuo, F Matsuda, E Vithana, M Seielstad, N Mizuki, RW Beuerman, ES Tai, N Yoshimura, T Aung, TL Young, TY Wong, YY Teo, SM Saw
Striatum Gene Expression Correlates for BEC measured in BXD RI Females & Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The BEC measures blood ethanol concentration in mg/dl under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C1HCOUNT60 measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C1HCOUNT60 measures Open Field locomotion 45-60 min post cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for NEPCOUNT45 measured in BXD RI Females obtained using INIA Brain mRNA M430 (Jun06) RMA. The NEPCOUNT45 measures Novel environment locomotion (activity beam breaks) 30-45 min in the periphery under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Whole Brain Gene Expression Correlates for NEPCOUNT60 measured in BXD RI Females obtained using INIA Brain mRNA M430 (Jun06) RMA. The NEPCOUNT60 measures Novel environment locomotion (activity beam breaks) 45-60 min in the periphery under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Whole Brain Gene Expression Correlates for NEPDIST45 measured in BXD RI Females obtained using INIA Brain mRNA M430 (Jun06) RMA. The NEPDIST45 measures Novel environment locomotion (cm) 30-45 min in the periphery under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Whole Brain Gene Expression Correlates for OF_HAB_RATIO measured in BXD RI Females obtained using INIA Brain mRNA M430 (Jun06) RMA. The OF_HAB_RATIO measures Open Field - Habituation ratio (First:Last intervals) under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for ACTI20_SAL measured in BXD RI Females obtained using INIA Brain mRNA M430 (Jun06) RMA. The ACTI20_SAL measures Distance traveled (cm) during the fourth five minute bin after saline under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Genes containing SNPs associated with Alcohol Dependence in Netherlands Study of Depression and Anxiety Sample. The analysis is a case-control study of 178 female and 140 male alcohol dependent cases and 929 female and 313 male controls. Alcohol dependence is defined as ever reporting a CAGE score > 2. Controls never reported a CAGE score > 2.
Authors:
Lind PA, Macgregor S, Vink JM, Pergadia ML, Hansell NK, de Moor MH, Smit AB, Hottenga JJ, Richter MM, Heath AC, Martin NG, Willemsen G, de Geus EJ, Vogelzangs N, Penninx BW, Whitfield JB, Montgomery GW, Boomsma DI, Madden PA
cocaine related behavior 2 (Cocrb2) spans 144.050573 - 194.050573 Mbp (NCBI Build 37) on Chr 1. Obtained from MGI (http://www.informatics.jax.org) by searching for QTLs containing the keyword .
QTL for ethanol conditioned taste aversion on Chr1 at NA (167.59 Mbp , Build 37)
Description:
ethanol conditioned taste aversion spans 142.59 - 192.59 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for cocaine related behavior on Chr1 at D1Ncvs12 (169.05 Mbp , Build 37)
Description:
cocaine related behavior spans 144.05 - 194.05 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for climbing on Chr1 at D1Ncvs12 (169.05 Mbp , Build 37)
Description:
METH responses for climbing spans 144.05 - 194.05 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for Acute ethanol sensitivity on Chr1 at NA (174.52 Mbp , Build 37)
Description:
Acute ethanol sensitivity spans 149.52 - 199.52 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Radcliffe RA, Bohl ML, Lowe MV, Cycowski CS, Wehner JM
QTL for differences in cocaine responsiveness on Chr1 at Mpmv-22 (181.89 Mbp , Build 37)
Description:
differences in cocaine responsiveness spans 156.89 - 206.89 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for differences in cocaine responsiveness on Chr1 at Pmv-21 (181.89 Mbp , Build 37)
Description:
differences in cocaine responsiveness spans 156.89 - 206.89 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for differences in cocaine responsiveness on Chr1 at D1MIt17 (181.89 Mbp , Build 37)
Description:
differences in cocaine responsiveness spans 156.89 - 206.89 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for activity response to ethanol on Chr1 at NA (184.43 Mbp , Build 37)
Description:
activity response to ethanol spans 159.43 - 209.43 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for morphine preference on Chr1 at NA (185.54 Mbp , Build 37)
Description:
morphine preference spans 160.54 - 210.54 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Berrettini WH, Ferraro TN, Alexander RC, Buchberg AM, Vogel WH
QTL for ethanol withdrawal on Chr1 at Xmv41 (190.14 Mbp , Build 37)
Description:
ethanol withdrawal spans 165.14 - 215.14 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for alcohol withdrawal on Chr1 at D1Mit206 (191.91 Mbp , Build 37)
Description:
alcohol withdrawal spans 166.91 - 216.91 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for ethanol induced locomotion on Chr1 at NA (200.10 Mbp , Build 37)
Description:
ethanol induced locomotion spans 175.10 - 225.10 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Hitzemann R, Demarest K, Koyner J, Cipp L, Patel N, Rasmussen E, McCaughran J Jr
QTL for alcohol consumption on Chr1 at D1Mit221 (204.10 Mbp , Build 37)
Description:
alcohol consumption spans 179.10 - 229.10 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Vadasz C, Saito M, Gyetvai B, Mikics E, Vadasz C 2nd
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