Retrovirus-associated DNA sequences (v-sis) originally isolated from the simian sarcoma virus (SSV). The proto-oncogene c-sis codes for a growth factor which is the B chain of PLATELET-DERIVED GROWTH FACTOR. v-sis or overexpression of c-sis causes tumorigenesis. The human sis gene is located at 22q12.3-13.1 on the long arm of chromosome 22.
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Cellular DNA-binding proteins encoded by the sis gene (GENES, SIS). c-sis proteins make up the B chain of PLATELET-DERIVED GROWTH FACTOR. Overexpression of c-sis causes tumorigenesis.
Generated by gene2mesh v. 1.1.1
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "citrate (Si)-synthase activity", which is defined as "Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the si-face of oxaloacetate; acetyl-CoA thus provides the two carbon atoms of the pro-S carboxymethyl group." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "citrate (Si)-synthase activity", which is defined as "Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the si-face of oxaloacetate; acetyl-CoA thus provides the two carbon atoms of the pro-S carboxymethyl group." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "citrate (Si)-synthase activity", which is defined as "Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the si-face of oxaloacetate; acetyl-CoA thus provides the two carbon atoms of the pro-S carboxymethyl group." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "citrate (Si)-synthase activity", which is defined as "Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the si-face of oxaloacetate; acetyl-CoA thus provides the two carbon atoms of the pro-S carboxymethyl group." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Genes associated with Homo sapiens that interact with the MeSH term 'si-wu-tang' (C403258). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Rattus norvegicus that interact with the MeSH term 'SI 27' (C421267). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Smoking behavior. The EFO term smoking behavior was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
SP David, A Hamidovic, GK Chen, AW Bergen, J Wessel, JL Kasberger, WM Brown, S Petruzella, EL Thacker, Y Kim, MA Nalls, GJ Tranah, YJ Sung, CB Ambrosone, D Arnett, EV Bandera, DM Becker, L Becker, SI Berndt, L Bernstein, WJ Blot, U Broeckel, SG Buxbaum, N Caporaso, G Casey, SJ Chanock, SL Deming, WR Diver, CB Eaton, DS Evans, MK Evans, M Fornage, N Franceschini, TB Harris, BE Henderson, DG Hernandez, B Hitsman, JJ Hu, SC Hunt, SA Ingles, EM John, R Kittles, S Kolb, LN Kolonel, L Le Marchand, Y Liu, KK Lohman, B McKnight, RC Millikan, A Murphy, C Neslund-Dudas, S Nyante, M Press, BM Psaty, DC Rao, S Redline, JL Rodriguez-Gil, BA Rybicki, LB Signorello, AB Singleton, J Smoller, B Snively, B Spring, JL Stanford, SS Strom, GE Swan, KD Taylor, MJ Thun, AF Wilson, JS Witte, Y Yamamura, LR Yanek, K Yu, W Zheng, RG Ziegler, AB Zonderman, E Jorgenson, CA Haiman, H Furberg
"Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the si-face of oxaloacetate; acetyl-CoA thus provides the two carbon atoms of the pro-S carboxymethyl group." [EC:2.3.3.1, ISBN:0121227073]
"Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the si-face of oxaloacetate; acetyl-CoA thus provides the two carbon atoms of the pro-S carboxymethyl group." [EC:2.3.3.1, ISBN:0121227073]
Genes with particular expression in the Substantia innominata. Data represent fold expression difference in structure versus grey matter average expression.
Enzyme that catalyzes the first step of the tricarboxylic acid cycle (CITRIC ACID CYCLE). It catalyzes the reaction of oxaloacetate and acetyl CoA to form citrate and coenzyme A. This enzyme was formerly listed as EC 4.1.3.7.
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Chronic alcohol exposure induced gene expression changes in the zebrafish brain. NimbleGen Array Zv7 385K mappings from various gene identifiers to ZFIN ID and fold change.
Using RNA-sequencing, we quantified whole-brain transcriptome levels in male zebrafish (five generations removed from the wild) treated with a racemic mixture of fluoxetine (n = 9) and control animals (n =10). Differential expression due to racemic fluoxetine treatment identified 411 significant genes.
Genes associated with Danio rerio that interact with the MeSH term 'Atrazine' (D001280). Incorporates data from 6 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Kyoto Encyclopedia of Genes and Genomes (KEGG) Geneset. This geneset contains genes that participate in the "Metabolic pathways" pathway. This set was automatically constructed using the KEGG API and enumerating all zebrafish pathways.
gene2kegg v. 0.1.2
Last updated 2018.01.17
Transcriptomic characterization of zebrafish larvae in response to mercury exposure. Uploaded all deferentially expressed genes from Table S3 with q-value.
Kyoto Encyclopedia of Genes and Genomes (KEGG) Geneset. This geneset contains genes that participate in the "Necroptosis" pathway. This set was automatically constructed using the KEGG API and enumerating all zebrafish pathways.
gene2kegg v. 0.1.2
Last updated 2018.01.17
Transcripts of zebrafish with p values for more accuracy and ease of use
sets include up and down regulated genes
Controls, MOs included within dataset
Transcripts of zebrafish with p values for more accuracy and ease of use
sets include up and down regulated genes
Controls, MOs included within dataset
Genes associated with Danio rerio that interact with the MeSH term 'bisphenol A' (C006780). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
GeneWeaver