List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Colorectal or endometrial cancer. The EFO term colorectal cancer, endometrial neoplasm was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
TH Cheng, D Thompson, J Painter, T O'Mara, M Gorman, L Martin, C Palles, A Jones, DD Buchanan, A Ko Win, J Hopper, M Jenkins, NM Lindor, PA Newcomb, S Gallinger, D Conti, F Schumacher, G Casey, GG Giles, P Pharoah, J Peto, A Cox, A Swerdlow, F Couch, JM Cunningham, EL Goode, SJ Winham, D Lambrechts, P Fasching, B Burwinkel, H Brenner, H Brauch, J Chang-Claude, HB Salvesen, V Kristensen, H Darabi, J Li, T Liu, A Lindblom, P Hall, ME de Polanco, M Sans, A Carracedo, S Castellvi-Bel, A Rojas-Martinez, S Aguiar Jnr, MR Teixeira, AM Dunning, J Dennis, G Otton, T Proietto, E Holliday, J Attia, K Ashton, RJ Scott, M McEvoy, SC Dowdy, BL Fridley, HM Werner, J Trovik, TS Njolstad, E Tham, M Mints, I Runnebaum, P Hillemanns, T Dörk, F Amant, S Schrauwen, A Hein, MW Beckmann, A Ekici, K Czene, A Meindl, MK Bolla, K Michailidou, JP Tyrer, Q Wang, S Ahmed, CS Healey, M Shah, D Annibali, J Depreeuw, NA Al-Tassan, R Harris, BF Meyer, N Whiffin, FJ Hosking, B Kinnersley, SM Farrington, M Timofeeva, A Tenesa, H Campbell, RW Haile, S Hodgson, L Carvajal-Carmona, JP Cheadle, D Easton, M Dunlop, R Houlston, A Spurdle, I Tomlinson
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Hypothyroidism. The EFO term hypothyroidism was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
N Eriksson, JY Tung, AK Kiefer, DA Hinds, U Francke, JL Mountain, CB Do
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Celiac disease. The EFO term celiac disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
KA Hunt, A Zhernakova, G Turner, GA Heap, L Franke, M Bruinenberg, J Romanos, LC Dinesen, AW Ryan, D Panesar, R Gwilliam, F Takeuchi, WM McLaren, GK Holmes, PD Howdle, JR Walters, DS Sanders, RJ Playford, G Trynka, CJ Mulder, ML Mearin, WH Verbeek, V Trimble, FM Stevens, C O'Morain, NP Kennedy, D Kelleher, DJ Pennington, DP Strachan, WL McArdle, CA Mein, MC Wapenaar, P Deloukas, R McGinnis, R McManus, C Wijmenga, DA van Heel
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Systolic blood pressure. The EFO term systolic blood pressure was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
D Levy, GB Ehret, K Rice, GC Verwoert, LJ Launer, A Dehghan, NL Glazer, AC Morrison, AD Johnson, T Aspelund, Y Aulchenko, T Lumley, A Köttgen, RS Vasan, F Rivadeneira, G Eiriksdottir, X Guo, DE Arking, GF Mitchell, FU Mattace-Raso, AV Smith, K Taylor, RB Scharpf, SJ Hwang, EJ Sijbrands, J Bis, TB Harris, SK Ganesh, CJ O'Donnell, A Hofman, JI Rotter, J Coresh, EJ Benjamin, AG Uitterlinden, G Heiss, CS Fox, JC Witteman, E Boerwinkle, TJ Wang, V Gudnason, MG Larson, A Chakravarti, BM Psaty, CM van Duijn
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Diastolic blood pressure. The EFO term diastolic blood pressure was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
D Levy, GB Ehret, K Rice, GC Verwoert, LJ Launer, A Dehghan, NL Glazer, AC Morrison, AD Johnson, T Aspelund, Y Aulchenko, T Lumley, A Köttgen, RS Vasan, F Rivadeneira, G Eiriksdottir, X Guo, DE Arking, GF Mitchell, FU Mattace-Raso, AV Smith, K Taylor, RB Scharpf, SJ Hwang, EJ Sijbrands, J Bis, TB Harris, SK Ganesh, CJ O'Donnell, A Hofman, JI Rotter, J Coresh, EJ Benjamin, AG Uitterlinden, G Heiss, CS Fox, JC Witteman, E Boerwinkle, TJ Wang, V Gudnason, MG Larson, A Chakravarti, BM Psaty, CM van Duijn
In this AAV association study, eight of the ten regions tested did not show an AAV association, with P values between 0.19 and 0.75 (table 1). Genotypes for all SNPs did not significantly deviate from Hardy-Weinberg equi- librium in either cases or controls.
Authors:
Carr EJ, Niederer HA, Williams J, Harper L, Watts RA, Lyons PA, Smith KG
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Hematocrit. The EFO term hematocrit was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
SK Ganesh, NA Zakai, FJ van Rooij, N Soranzo, AV Smith, MA Nalls, MH Chen, A Kottgen, NL Glazer, A Dehghan, B Kuhnel, T Aspelund, Q Yang, T Tanaka, A Jaffe, JC Bis, GC Verwoert, A Teumer, CS Fox, JM Guralnik, GB Ehret, K Rice, JF Felix, A Rendon, G Eiriksdottir, D Levy, KV Patel, E Boerwinkle, JI Rotter, A Hofman, JG Sambrook, DG Hernandez, G Zheng, S Bandinelli, AB Singleton, J Coresh, T Lumley, AG Uitterlinden, JM Vangils, LJ Launer, LA Cupples, BA Oostra, JJ Zwaginga, WH Ouwehand, SL Thein, C Meisinger, P Deloukas, M Nauck, TD Spector, C Gieger, V Gudnason, CM van Duijn, BM Psaty, L Ferrucci, A Chakravarti, A Greinacher, CJ O'Donnell, JC Witteman, S Furth, M Cushman, TB Harris, JP Lin
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Celiac disease or Rheumatoid arthritis. The EFO term immune system disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
A Zhernakova, EA Stahl, G Trynka, S Raychaudhuri, EA Festen, L Franke, HJ Westra, RS Fehrmann, FA Kurreeman, B Thomson, N Gupta, J Romanos, R McManus, AW Ryan, G Turner, E Brouwer, MD Posthumus, EF Remmers, F Tucci, R Toes, E Grandone, MC Mazzilli, A Rybak, B Cukrowska, MJ Coenen, TR Radstake, PL van Riel, Y Li, PI de Bakker, PK Gregersen, J Worthington, KA Siminovitch, L Klareskog, TW Huizinga, C Wijmenga, RM Plenge
GWAS: type I diabetes mellitus, autoantibody measurement
Description:
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Type 1 diabetes autoantibodies. The EFO term type I diabetes mellitus, autoantibody measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
V Plagnol, JM Howson, DJ Smyth, N Walker, JP Hafler, C Wallace, H Stevens, L Jackson, MJ Simmonds, PJ Bingley, SC Gough, JA Todd
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Soluble ICAM-1. The EFO term ICAM-1 measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Diastolic blood pressure. The EFO term diastolic blood pressure was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
C Newton-Cheh, T Johnson, V Gateva, MD Tobin, M Bochud, L Coin, SS Najjar, JH Zhao, SC Heath, S Eyheramendy, K Papadakis, BF Voight, LJ Scott, F Zhang, M Farrall, T Tanaka, C Wallace, JC Chambers, KT Khaw, P Nilsson, P van der Harst, S Polidoro, DE Grobbee, NC Onland-Moret, ML Bots, LV Wain, KS Elliott, A Teumer, J Luan, G Lucas, J Kuusisto, PR Burton, D Hadley, WL McArdle, M Brown, A Dominiczak, SJ Newhouse, NJ Samani, J Webster, E Zeggini, JS Beckmann, S Bergmann, N Lim, K Song, P Vollenweider, G Waeber, DM Waterworth, X Yuan, L Groop, M Orho-Melander, A Allione, A Di Gregorio, S Guarrera, S Panico, F Ricceri, V Romanazzi, C Sacerdote, P Vineis, I Barroso, MS Sandhu, RN Luben, GJ Crawford, P Jousilahti, M Perola, M Boehnke, LL Bonnycastle, FS Collins, AU Jackson, KL Mohlke, HM Stringham, TT Valle, CJ Willer, RN Bergman, MA Morken, A Döring, C Gieger, T Illig, T Meitinger, E Org, A Pfeufer, HE Wichmann, S Kathiresan, J Marrugat, CJ O'Donnell, SM Schwartz, DS Siscovick, I Subirana, NB Freimer, AL Hartikainen, MI McCarthy, PF O'Reilly, L Peltonen, A Pouta, PE de Jong, H Snieder, WH van Gilst, R Clarke, A Goel, A Hamsten, JF Peden, U Seedorf, AC Syvänen, G Tognoni, EG Lakatta, S Sanna, P Scheet, D Schlessinger, A Scuteri, M Dörr, F Ernst, SB Felix, G Homuth, R Lorbeer, T Reffelmann, R Rettig, U Völker, P Galan, IG Gut, S Hercberg, GM Lathrop, D Zelenika, P Deloukas, N Soranzo, FM Williams, G Zhai, V Salomaa, M Laakso, R Elosua, NG Forouhi, H Völzke, CS Uiterwaal, YT van der Schouw, ME Numans, G Matullo, G Navis, G Berglund, SA Bingham, JS Kooner, JM Connell, S Bandinelli, L Ferrucci, H Watkins, TD Spector, J Tuomilehto, D Altshuler, DP Strachan, M Laan, P Meneton, NJ Wareham, M Uda, MR Jarvelin, V Mooser, O Melander, RJ Loos, P Elliott, GR Abecasis, M Caulfield, PB Munroe
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Peripheral artery disease. The EFO term peripheral arterial disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
IJ Kullo, K Shameer, H Jouni, TG Lesnick, J Pathak, CG Chute, M de Andrade
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Vitiligo. The EFO term Vitiligo was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
Y Jin, SA Birlea, PR Fain, TM Ferrara, S Ben, SL Riccardi, JB Cole, K Gowan, PJ Holland, DC Bennett, RM Luiten, A Wolkerstorfer, JP van der Veen, A Hartmann, S Eichner, G Schuler, N van Geel, J Lambert, EH Kemp, DJ Gawkrodger, AP Weetman, A Taïeb, T Jouary, K Ezzedine, MR Wallace, WT McCormack, M Picardo, G Leone, A Overbeck, NB Silverberg, RA Spritz
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Retinal vascular caliber. The EFO term eye measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
MK Ikram, X Sim, S Xueling, RA Jensen, MF Cotch, AW Hewitt, MA Ikram, JJ Wang, R Klein, BE Klein, MM Breteler, N Cheung, G Liew, P Mitchell, AG Uitterlinden, F Rivadeneira, A Hofman, PT de Jong, CM van Duijn, L Kao, CY Cheng, AV Smith, NL Glazer, T Lumley, B McKnight, BM Psaty, F Jonasson, G Eiriksdottir, T Aspelund, TB Harris, LJ Launer, KD Taylor, X Li, SK Iyengar, Q Xi, TA Sivakumaran, DA Mackey, S Macgregor, NG Martin, TL Young, JC Bis, KL Wiggins, SR Heckbert, CJ Hammond, T Andrew, S Fahy, J Attia, EG Holliday, RJ Scott, FM Islam, JI Rotter, AK McAuley, E Boerwinkle, ES Tai, V Gudnason, DS Siscovick, JR Vingerling, TY Wong
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Platelet count. The EFO term platelet count was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Eosinophil counts. The EFO term eosinophil count was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
DF Gudbjartsson, US Bjornsdottir, E Halapi, A Helgadottir, P Sulem, GM Jonsdottir, G Thorleifsson, H Helgadottir, V Steinthorsdottir, H Stefansson, C Williams, J Hui, J Beilby, NM Warrington, A James, LJ Palmer, GH Koppelman, A Heinzmann, M Krueger, HM Boezen, A Wheatley, J Altmuller, HD Shin, ST Uh, HS Cheong, B Jonsdottir, D Gislason, CS Park, LM Rasmussen, C Porsbjerg, JW Hansen, V Backer, T Werge, C Janson, UB Jönsson, MC Ng, J Chan, WY So, R Ma, SH Shah, CB Granger, AA Quyyumi, AI Levey, V Vaccarino, MP Reilly, DJ Rader, MJ Williams, AM van Rij, GT Jones, E Trabetti, G Malerba, PF Pignatti, A Boner, L Pescollderungg, D Girelli, O Olivieri, N Martinelli, BR Ludviksson, D Ludviksdottir, GI Eyjolfsson, D Arnar, G Thorgeirsson, K Deichmann, PJ Thompson, M Wjst, IP Hall, DS Postma, T Gislason, J Gulcher, A Kong, I Jonsdottir, U Thorsteinsdottir, K Stefansson
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Beta-2 microglubulin plasma levels. The EFO term beta-2 microglobulin measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
A Tin, BC Astor, E Boerwinkle, RC Hoogeveen, J Coresh, WH Kao
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Hypertension. The EFO term hypertension was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
D Levy, GB Ehret, K Rice, GC Verwoert, LJ Launer, A Dehghan, NL Glazer, AC Morrison, AD Johnson, T Aspelund, Y Aulchenko, T Lumley, A Köttgen, RS Vasan, F Rivadeneira, G Eiriksdottir, X Guo, DE Arking, GF Mitchell, FU Mattace-Raso, AV Smith, K Taylor, RB Scharpf, SJ Hwang, EJ Sijbrands, J Bis, TB Harris, SK Ganesh, CJ O'Donnell, A Hofman, JI Rotter, J Coresh, EJ Benjamin, AG Uitterlinden, G Heiss, CS Fox, JC Witteman, E Boerwinkle, TJ Wang, V Gudnason, MG Larson, A Chakravarti, BM Psaty, CM van Duijn
Striatum Gene Expression Correlates for HOTPLATE_MEANOF2 measured in BXD RI Females & Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The HOTPLATE_MEANOF2 measures Thermal Nociception Hot Plate Avg of 2Trials under the domain Pain. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for COCA_TIME_COND_CHG measured in BXD RI Females & Males obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The COCA_TIME_COND_CHG measures Cocaine CPP - difference in time spent relative to baseline drug exposure under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for COCA_TIME_COND_CHG measured in BXD RI Females obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The COCA_TIME_COND_CHG measures Cocaine CPP - difference in time spent relative to baseline drug exposure under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Genes with a mean fold change > 1.5 or < 0.7 were selected and annotated. Values are taken from microarray analysis and represent mean ratios of alcoholic cases compared with matched control cases(n = 6). P values were from t-test; from Flatscher-Bader et al., 2005
Authors:
Flatscher-Bader T, van der Brug M, Hwang JW, Gochee PA, Matsumoto I, Niwa S, Wilce PA
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