List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Systemic lupus erythematosus. The EFO term systemic lupus erythematosus was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JB Harley, ME Alarcón-Riquelme, LA Criswell, CO Jacob, RP Kimberly, KL Moser, BP Tsao, TJ Vyse, CD Langefeld, SK Nath, JM Guthridge, BL Cobb, DB Mirel, MC Marion, AH Williams, J Divers, W Wang, SG Frank, B Namjou, SB Gabriel, AT Lee, PK Gregersen, TW Behrens, KE Taylor, M Fernando, R Zidovetzki, PM Gaffney, JC Edberg, JD Rioux, JO Ojwang, JA James, JT Merrill, GS Gilkeson, MF Seldin, H Yin, EC Baechler, QZ Li, EK Wakeland, GR Bruner, KM Kaufman, JA Kelly
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Systemic lupus erythematosus and Systemic sclerosis. The EFO term systemic lupus erythematosus was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JE Martin, S Assassi, LM Diaz-Gallo, JC Broen, CP Simeon, I Castellvi, E Vicente-Rabaneda, V Fonollosa, N Ortego-Centeno, MA González-Gay, G Espinosa, P Carreira, M Camps, JM Sabio, S D'alfonso, MC Vonk, AE Voskuyl, AJ Schuerwegh, A Kreuter, T Witte, G Riemekasten, N Hunzelmann, P Airo, L Beretta, R Scorza, C Lunardi, J Van Laar, MM Chee, J Worthington, A Herrick, C Denton, C Fonseca, FK Tan, F Arnett, X Zhou, JD Reveille, O Gorlova, BP Koeleman, TR Radstake, T Vyse, MD Mayes, ME Alarcón-Riquelme, J Martin
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Rheumatoid arthritis. The EFO term rheumatoid arthritis was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
EA Stahl, S Raychaudhuri, EF Remmers, G Xie, S Eyre, BP Thomson, Y Li, FA Kurreeman, A Zhernakova, A Hinks, C Guiducci, R Chen, L Alfredsson, CI Amos, KG Ardlie, A Barton, J Bowes, E Brouwer, NP Burtt, JJ Catanese, J Coblyn, MJ Coenen, KH Costenbader, LA Criswell, JB Crusius, J Cui, PI de Bakker, PL De Jager, B Ding, P Emery, E Flynn, P Harrison, LJ Hocking, TW Huizinga, DL Kastner, X Ke, AT Lee, X Liu, P Martin, AW Morgan, L Padyukov, MD Posthumus, TR Radstake, DM Reid, M Seielstad, MF Seldin, NA Shadick, S Steer, PP Tak, W Thomson, AH van der Helm-van Mil, IE van der Horst-Bruinsma, CE van der Schoot, PL van Riel, ME Weinblatt, AG Wilson, GJ Wolbink, BP Wordsworth, C Wijmenga, EW Karlson, RE Toes, N de Vries, AB Begovich, J Worthington, KA Siminovitch, PK Gregersen, L Klareskog, RM Plenge
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Systemic lupus erythematosus and Systemic sclerosis. The EFO term systemic scleroderma, systemic lupus erythematosus was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JE Martin, S Assassi, LM Diaz-Gallo, JC Broen, CP Simeon, I Castellvi, E Vicente-Rabaneda, V Fonollosa, N Ortego-Centeno, MA González-Gay, G Espinosa, P Carreira, M Camps, JM Sabio, S D'alfonso, MC Vonk, AE Voskuyl, AJ Schuerwegh, A Kreuter, T Witte, G Riemekasten, N Hunzelmann, P Airo, L Beretta, R Scorza, C Lunardi, J Van Laar, MM Chee, J Worthington, A Herrick, C Denton, C Fonseca, FK Tan, F Arnett, X Zhou, JD Reveille, O Gorlova, BP Koeleman, TR Radstake, T Vyse, MD Mayes, ME Alarcón-Riquelme, J Martin
Whole Brain Gene Expression Correlates for ACTITOT_DIFF measured in BXD RI Females & Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The ACTITOT_DIFF measures Difference in total distance traveled (cm) (saline-ethanol) under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for ACTITOT_DIFF measured in BXD RI Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The ACTITOT_DIFF measures Difference in total distance traveled (cm) (saline-ethanol) under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Differentially expressed in the Nucleus accumbens following 24 hr continuous 9.5g/kg/day alcohol drinking vs. water drinking in alcohol preferring rats. Estimated BAC in the alcohol exposed group was > 85mg%. The 406 significanlty different probe sets represent 374 uniquely named genes, with most gene expression differences in the range of 1.1-1.3 fold.
Renthal W, Kumar A, Xiao G, Wilkinson M, Covington HE 3rd, Maze I, Sikder D, Robison AJ, LaPlant Q, Dietz DM, Russo SJ, Vialou V, Chakravarty S, Kodadek TJ, Stack A, Kabbaj M, Nestler EJ
QTL for high-dose ethanol actions on Chr14 at D14Mit1 (5.65 Mbp , Build 37)
Description:
high-dose ethanol actions spans 0.00 - 30.65 Mbp (NCBI Build 37) on Chr14. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Erwin VG, Markel PD, Johnson TE, Gehle VM, Jones BC
QTL for METH responses for chewing on Chr14 at D14Mit54 (23.48 Mbp , Build 37)
Description:
METH responses for chewing spans 0.00 - 48.48 Mbp (NCBI Build 37) on Chr14. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for body temperature on Chr14 at Glud (26.89 Mbp , Build 37)
Description:
METH responses for body temperature spans 1.89 - 51.89 Mbp (NCBI Build 37) on Chr14. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for home cage activity on Chr14 at Mtv11 (27.12 Mbp , Build 37)
Description:
METH responses for home cage activity spans 2.12 - 52.12 Mbp (NCBI Build 37) on Chr14. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for home cage activity on Chr14 at Ms15-7 (28.18 Mbp , Build 37)
Description:
METH responses for home cage activity spans 3.18 - 53.18 Mbp (NCBI Build 37) on Chr14. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Genes associated with Oryctolagus cuniculus that interact with the MeSH term 'Ionomycin' (D015759). Incorporates data from 6 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Dexamethasone' (D003907). Incorporates data from 14 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine' (C516138). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'vorinostat' (C111237). Incorporates data from 13 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Melphalan' (D008558). Incorporates data from 2 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Platichthys flesus that interact with the MeSH term 'pentabromodiphenyl ether' (C086401). Incorporates data from 4 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
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