Striatum Gene Expression Correlates for LD_PCT_LIGHT_TIME measured in BXD RI Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The LD_PCT_LIGHT_TIME measures Light-Dark Box Percentage time in light under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for OF_REAR_15_20 measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The OF_REAR_15_20 measures Open Field - Total rears 15-20 minutes under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
QTL for nicotine sensitivity on Chr14 at D14Mit155 (49.05 Mbp , Build 37)
Description:
nicotine sensitivity spans 24.05 - 74.05 Mbp (NCBI Build 37) on Chr14. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for home cage activity on Chr14 at Gnrh (75.38 Mbp , Build 37)
Description:
METH responses for home cage activity spans 50.38 - 100.38 Mbp (NCBI Build 37) on Chr14. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for chronic alcohol withdrawal severity on Chr14 at D14mit160 (75.81 Mbp , Build 37)
Description:
chronic alcohol withdrawal severity spans 50.81 - 100.81 Mbp (NCBI Build 37) on Chr14. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Bergeson SE, Kyle Warren R, Crabbe JC, Metten P, Gene Erwin V, Belknap JK
QTL for METH responses for climbing on Chr14 at Es10 (78.19 Mbp , Build 37)
Description:
METH responses for climbing spans 53.19 - 103.19 Mbp (NCBI Build 37) on Chr14. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
None - Schizophrenic vs. Control Quantitative reverse transcriptase-polymerase chain reaction Change in gene expression Postmortem parameters, such as age, sex, ethnicity, medication history, mental illness status, cigarette smoking history, and alcohol use, were evaluated through hospital, autopsy, and neuropathology reports. Family members and physicians were also interviewed to detail the smoking and alcohol history of the subject, including packs of cigarettes smoked per day, and the quantity and type of alcohol consumed. All of the subjects who had used alcohol prior to death had consumed no more than two dr two-way ANOVA; Fisher's exact test; Student's t test Values for each sample were normalized to GAPDH. Relative expression values were log10 transformed and differences in mean gene expression were determined using a Student's t test (P < 0.05). For QRT-PCR results, mean relative mRNA amounts +/- standard error of the mean (SEM) for each experimental group were graphed in Sigma Plot 2000. (NIF Method ID 129)
Authors:
Mexal S, Frank M, Berger R, Adams CE, Ross RG, Freedman R, Leonard S
Chronic nicotine - Nicotine vs. Control Quantitative reverse transcriptase-polymerase chain reaction Change in gene expression Postmortem parameters, such as age, sex, ethnicity, medication history, mental illness status, cigarette smoking history, and alcohol use, were evaluated through hospital, autopsy, and neuropathology reports. Family members and physicians were also interviewed to detail the smoking and alcohol history of the subject, including packs of cigarettes smoked per day, and the quantity and type of alcohol consumed. All of the subjects who had used alcohol prior to death had consumed no more than two dr two-way ANOVA; Fisher's exact test; Student's t test Values for each sample were normalized to GAPDH. Relative expression values were log10 transformed and differences in mean gene expression were determined using a Student's t test (P < 0.05). For QRT-PCR results, mean relative mRNA amounts +/- standard error of the mean (SEM) for each experimental group were graphed in Sigma Plot 2000. (NIF Method ID 130)
Authors:
Mexal S, Frank M, Berger R, Adams CE, Ross RG, Freedman R, Leonard S
Chronic nicotine - Schizophrenic vs. Control Quantitative reverse transcriptase-polymerase chain reaction Change in gene expression Postmortem parameters, such as age, sex, ethnicity, medication history, mental illness status, cigarette smoking history, and alcohol use, were evaluated through hospital, autopsy, and neuropathology reports. Family members and physicians were also interviewed to detail the smoking and alcohol history of the subject, including packs of cigarettes smoked per day, and the quantity and type of alcohol consumed. All of the subjects who had used alcohol prior to death had consumed no more than two dr two-way ANOVA; Fisher's exact test; Student's t test Values for each sample were normalized to GAPDH. Relative expression values were log10 transformed and differences in mean gene expression were determined using a Student's t test (P < 0.05). For QRT-PCR results, mean relative mRNA amounts +/- standard error of the mean (SEM) for each experimental group were graphed in Sigma Plot 2000. (NIF Method ID 131)
Authors:
Mexal S, Frank M, Berger R, Adams CE, Ross RG, Freedman R, Leonard S
Genes associated with Oryctolagus cuniculus that interact with the MeSH term 'Ionomycin' (D015759). Incorporates data from 6 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Coumestrol' (D003375). Incorporates data from 6 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Vitamin K 3' (D024483). Incorporates data from 82 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine' (C516138). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '2,3-bis(3'-hydroxybenzyl)butyrolactone' (C029497). Incorporates data from 2 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'cobaltous chloride' (C018021). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Cyclosporine' (D016572). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Curcumin' (D003474). Incorporates data from 6 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Hydrogen Peroxide' (D006861). Incorporates data from 4 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'potassium chromate(VI)' (C027373). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide' (C459179). Incorporates data from 9 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
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