List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Body fat percentage. The EFO term body fat percentage was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
Y Lu, FR Day, S Gustafsson, ML Buchkovich, J Na, V Bataille, DL Cousminer, Z Dastani, AW Drong, T Esko, DM Evans, M Falchi, MF Feitosa, T Ferreira, ÅK Hedman, R Haring, PG Hysi, MM Iles, AE Justice, S Kanoni, V Lagou, R Li, X Li, A Locke, C Lu, R Mägi, JR Perry, TH Pers, Q Qi, M Sanna, EM Schmidt, WR Scott, D Shungin, A Teumer, AA Vinkhuyzen, RW Walker, HJ Westra, M Zhang, W Zhang, JH Zhao, Z Zhu, U Afzal, TS Ahluwalia, SJ Bakker, C Bellis, A Bonnefond, K Borodulin, AS Buchman, T Cederholm, AC Choh, HJ Choi, JE Curran, LC de Groot, PL De Jager, RA Dhonukshe-Rutten, AW Enneman, E Eury, DS Evans, T Forsen, N Friedrich, F Fumeron, ME Garcia, S Gärtner, BG Han, AS Havulinna, C Hayward, D Hernandez, H Hillege, T Ittermann, JW Kent, I Kolcic, T Laatikainen, J Lahti, I Mateo Leach, CG Lee, JY Lee, T Liu, Y Liu, S Lobbens, M Loh, LP Lyytikäinen, C Medina-Gomez, K Michaëlsson, MA Nalls, CM Nielson, L Oozageer, L Pascoe, L Paternoster, O Polašek, S Ripatti, MA Sarzynski, CS Shin, NS Narančić, D Spira, P Srikanth, E Steinhagen-Thiessen, YJ Sung, KM Swart, L Taittonen, T Tanaka, E Tikkanen, N van der Velde, NM van Schoor, N Verweij, AF Wright, L Yu, JM Zmuda, N Eklund, T Forrester, N Grarup, AU Jackson, K Kristiansson, T Kuulasmaa, J Kuusisto, P Lichtner, J Luan, A Mahajan, S Männistö, CD Palmer, JS Ried, RA Scott, A Stancáková, PJ Wagner, A Demirkan, A Döring, V Gudnason, DP Kiel, B Kühnel, M Mangino, B Mcknight, C Menni, JR O'Connell, BA Oostra, AR Shuldiner, K Song, L Vandenput, CM van Duijn, P Vollenweider, CC White, M Boehnke, Y Boettcher, RS Cooper, NG Forouhi, C Gieger, H Grallert, A Hingorani, T Jørgensen, P Jousilahti, M Kivimaki, M Kumari, M Laakso, C Langenberg, A Linneberg, A Luke, CA Mckenzie, A Palotie, O Pedersen, A Peters, K Strauch, BO Tayo, NJ Wareham, DA Bennett, L Bertram, J Blangero, M Blüher, C Bouchard, H Campbell, NH Cho, SR Cummings, SA Czerwinski, I Demuth, R Eckardt, JG Eriksson, L Ferrucci, OH Franco, P Froguel, RT Gansevoort, T Hansen, TB Harris, N Hastie, M Heliövaara, A Hofman, JM Jordan, A Jula, M Kähönen, E Kajantie, PB Knekt, S Koskinen, P Kovacs, T Lehtimäki, L Lind, Y Liu, ES Orwoll, C Osmond, M Perola, L Pérusse, OT Raitakari, T Rankinen, DC Rao, TK Rice, F Rivadeneira, I Rudan, V Salomaa, TI Sørensen, M Stumvoll, A Tönjes, B Towne, GJ Tranah, A Tremblay, AG Uitterlinden, P van der Harst, E Vartiainen, JS Viikari, V Vitart, MC Vohl, H Völzke, M Walker, H Wallaschofski, S Wild, JF Wilson, L Yengo, DT Bishop, IB Borecki, JC Chambers, LA Cupples, A Dehghan, P Deloukas, G Fatemifar, C Fox, TS Furey, L Franke, J Han, DJ Hunter, J Karjalainen, F Karpe, RC Kaplan, JS Kooner, MI McCarthy, JM Murabito, AP Morris, JA Bishop, KE North, C Ohlsson, KK Ong, I Prokopenko, JB Richards, EE Schadt, TD Spector, E Widén, CJ Willer, J Yang, E Ingelsson, KL Mohlke, JN Hirschhorn, JA Pospisilik, MC Zillikens, C Lindgren, TO Kilpeläinen, RJ Loos
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Cutaneous nevi. The EFO term nevus was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
M Falchi, V Bataille, NK Hayward, DL Duffy, JA Bishop, T Pastinen, A Cervino, ZZ Zhao, P Deloukas, N Soranzo, DE Elder, JH Barrett, NG Martin, DT Bishop, GW Montgomery, TD Spector
This gene set comprises 399 genes that are differentially expressed within each of five brain regions (amygdale, hippocampus, nucleus accumbens, prefrontal cortex and ventral tegmental area) when chronic nicotine treatment is administered to C3H/HeJ mice only. Background: Studies involving use of chronic nicotine treatment identify unique nicotine addiction genes and the biological processes they control in B6 and C3 mice. Results are obtained using gene expression profiling and gene ontology.
Authors:
Wang J, Gutala R, Hwang YY, Kim JM, Konu O, Ma JZ, Li MD
This gene set comprises 239 genes that are differentially expressed within each of five brain regions (amygdala, hippocampus, nucleus accumbens, prefrontal cortex and ventral tegmental area) when chronic nicotine treatment is administered to C57BL/6J mice only. Background: Studies involving use of chronic nicotine treatment identify unique nicotine addiction genes and the biological processes they control in B6 and C3 mice. Results are obtained using gene expression profiling and gene ontology.
Authors:
Wang J, Gutala R, Hwang YY, Kim JM, Konu O, Ma JZ, Li MD
This gene set comprises 25 genes that are downregulated within each of five brain regions (amygdale (Amyg), hippocampus (HP), nucleus accumbens (NA), prefrontal cortex (PFC) and ventral tegmental area (VTA)) when chronic nicotine treatment is administered to C57BL/6J mice only. Background: Studies involving use of chronic nicotine treatment identify unique nicotine addiction genes and the biological processes they mediate in C3H/HeJ and C57BL/6J mice. Results are obtained using gene expression profiling via cDNA microarrays and gene ontology.
Authors:
Wang J, Gutala R, Hwang YY, Kim JM, Konu O, Ma JZ, Li MD
Striatum Gene Expression Correlates for AMDIST30 measured in BXD RI Females & Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The AMDIST30 measures Morphine distance (cm) travelled minutes 15-30 under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for AMDIST45 measured in BXD RI Females & Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The AMDIST45 measures Morphine distance (cm) travelled minutes 30-45 under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for AMDIST60 measured in BXD RI Females & Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The AMDIST60 measures Morphine distance (cm) travelled minutes 45-60 under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for AMDIST75 measured in BXD RI Females & Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The AMDIST75 measures Morphine distance (cm) travelled minutes 60-75 under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for LM_CUE_SUPPRESS measured in BXD RI Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The LM_CUE_SUPPRESS measures Suppression of activity in altered context under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for LM_CUE_SUPPRESS measured in BXD RI Males obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The LM_CUE_SUPPRESS measures Suppression of activity in altered context under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for HAND_7HOURS measured in BXD RI Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The HAND_7HOURS measures Handling induced convulsions 7 hrs after ethanol under the domain Ethanol HIC. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for HIC_SCORE measured in BXD RI Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The HIC_SCORE measures Handling induced convulsion score under the domain Ethanol HIC. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for SALIVA measured in BXD RI Males obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The SALIVA measures Morphine - Salivation under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
cocaine related behavior 14 (Cocrb14) spans 43.765096 - 93.765096 Mbp (NCBI Build 37) on Chr 15. Obtained from MGI (http://www.informatics.jax.org) by searching for QTLs containing the keyword .
cocaine related behavior 15 (Cocrb15) spans 70.807693 - 120.807693 Mbp (NCBI Build 37) on Chr 15. Obtained from MGI (http://www.informatics.jax.org) by searching for QTLs containing the keyword .
QTL for alcohol acceptance on Chr15 at D15Mit60 (57.48 Mbp , Build 37)
Description:
alcohol acceptance spans 32.48 - 82.48 Mbp (NCBI Build 37) on Chr15. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
McClearn GE, Tarantino LM, Rodriguez LA, Jones BC, Blizard DA, Plomin R
QTL for cocaine related behavior on Chr15 at D15Mit3 (83.88 Mbp , Build 37)
Description:
cocaine related behavior spans 58.88 - 108.88 Mbp (NCBI Build 37) on Chr15. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for alcohol consumption on Chr15 at D15Mit105 (87.33 Mbp , Build 37)
Description:
alcohol consumption spans 62.33 - 112.33 Mbp (NCBI Build 37) on Chr15. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Vadasz C, Saito M, Gyetvai B, Mikics E, Vadasz C 2nd
QTL for cocaine induced activation on Chr15 at NA (92.79 Mbp , Build 37)
Description:
cocaine induced activation spans 67.79 - 117.79 Mbp (NCBI Build 37) on Chr15. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for home cage activity on Chr15 at D15Mit1 (93.20 Mbp , Build 37)
Description:
METH responses for home cage activity spans 68.20 - 118.20 Mbp (NCBI Build 37) on Chr15. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
GeneWeaver