QTL associated with Y-linked autoimmune acceleration QTL 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (56424004)
Authors:
Laporte C, Ballester B, Mary C, Izui S, Reininger L
QTL associated with spacial bias during navigation task 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (46945614)
QTL associated with spontaneous crescentic glomerulonephritis QTL 5. The confidence interval is Chr13:35968794-96872609 bp,+strand
Authors:
Hamano Y, Tsukamoto K, Abe M, Sun GD, Zhang D, Fujii H, Matsuoka S, Tanaka M, Ishida-Okawara A, Tachikawa H, Nishimura H, Tokunaka K, Hirose S, Suzuki K
QTL associated with "cerebellum pattern fissures, declival 5". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (56582797)
QTL associated with circadian period of locomotor activity 11. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (55673906)
Authors:
Hofstetter JR, Trofatter JA, Kernek KL, Nurnberger JI, Mayeda AR
QTL associated with Crh transcript abundance QTL 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (56786703)
Differential gene expression in nucleus accumbens somatostatin interneurons_cocaine_mice_pvalue
Description:
To characterize transcriptional alterations that cocaine induces in these cells, we perform cell type-specific RNA-sequencing on FACS-isolated nuclei of somatostatin interneurons and identified 1100 DETs enriched for processes related to neural plasticity. To profile the entire (non poly-A selected) transcriptome of NAc somatostatin interneurons, we generated a transgenic reporter line (SST-TLG498 mice) to label the nuclei of these cells with a modified form of EGFP that is retained in the nuclear membrane (EGFP-F)22, enabling their isolation from NAc dissections using FACS. We succeeded in FACS-isolating nuclei suitable for RNA-sequencing from individual SST-TLG498 mice. We proceeded with differential expression analysis of the RNA-sequencing data to identify differentially expressed transcripts (DETs) in NAc somatostatin interneurons in response to repeated cocaine exposure: 778 transcripts were upregulated by cocaine and 322 were downregulated.
Authors:
Efrain A Ribeiro, Marine Salery, Joseph R Scarpa, Erin S Calipari, Peter J Hamilton, Stacy M Ku, Hope Kronman, Immanuel Purushothaman, Barbara Juarez, Mitra Heshmati, Marie Doyle, Casey Lardner, Dominicka Burek, Ana Strat, Stephen Pirpinias, Ezekiell Mouzon, Ming-Hu Han, Rachael L Neve, Rosemary C Bagot, Andrew Kasarskis, Ja Wook Koo, Eric J Nestler
QTL associated with primordial germ cell tumor locus 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (70811542)
Genes associated with Homo sapiens that interact with the MeSH term '(4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II)' (C517041). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
QTL associated with voluntary alcohol consumption QTL 5. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (37033374)
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The processes, properties and biological objects that are involved in maintaining, expressing, and transmitting from one organism to another, genetically encoded traits.
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Kyoto Encyclopedia of Genes and Genomes (KEGG) Geneset. This geneset contains genes that participate in the "MicroRNAs in cancer" pathway. This set was automatically constructed using the KEGG API and enumerating all mouse pathways.
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Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.
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Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.
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