GWAS: pulmonary function measurement, FEV/FEC ratio
Description:
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Pulmonary function. The EFO term pulmonary function measurement, FEV/FEC ratio was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
M Soler Artigas, DW Loth, LV Wain, SA Gharib, M Obeidat, W Tang, G Zhai, JH Zhao, AV Smith, JE Huffman, E Albrecht, CM Jackson, DM Evans, G Cadby, M Fornage, A Manichaikul, LM Lopez, T Johnson, MC Aldrich, T Aspelund, I Barroso, H Campbell, PA Cassano, DJ Couper, G Eiriksdottir, N Franceschini, M Garcia, C Gieger, GK Gislason, I Grkovic, CJ Hammond, DB Hancock, TB Harris, A Ramasamy, SR Heckbert, M Heliövaara, G Homuth, PG Hysi, AL James, S Jankovic, BR Joubert, S Karrasch, N Klopp, B Koch, SB Kritchevsky, LJ Launer, Y Liu, LR Loehr, K Lohman, RJ Loos, T Lumley, KA Al Balushi, WQ Ang, RG Barr, J Beilby, JD Blakey, M Boban, V Boraska, J Brisman, JR Britton, GG Brusselle, C Cooper, I Curjuric, S Dahgam, IJ Deary, S Ebrahim, M Eijgelsheim, C Francks, D Gaysina, R Granell, X Gu, JL Hankinson, R Hardy, SE Harris, J Henderson, A Henry, AD Hingorani, A Hofman, PG Holt, J Hui, ML Hunter, M Imboden, KA Jameson, SM Kerr, I Kolcic, F Kronenberg, JZ Liu, J Marchini, T McKeever, AD Morris, AC Olin, DJ Porteous, DS Postma, SS Rich, SM Ring, F Rivadeneira, T Rochat, AA Sayer, I Sayers, PD Sly, GD Smith, A Sood, JM Starr, AG Uitterlinden, JM Vonk, SG Wannamethee, PH Whincup, C Wijmenga, OD Williams, A Wong, M Mangino, KD Marciante, WL McArdle, B Meibohm, AC Morrison, KE North, E Omenaas, LJ Palmer, KH Pietiläinen, I Pin, O Pola Sbreve Ek, A Pouta, BM Psaty, AL Hartikainen, T Rantanen, S Ripatti, JI Rotter, I Rudan, AR Rudnicka, H Schulz, SY Shin, TD Spector, I Surakka, V Vitart, H Völzke, NJ Wareham, NM Warrington, HE Wichmann, SH Wild, JB Wilk, M Wjst, AF Wright, L Zgaga, T Zemunik, CE Pennell, F Nyberg, D Kuh, JW Holloway, HM Boezen, DA Lawlor, RW Morris, N Probst-Hensch, J Kaprio, JF Wilson, C Hayward, M Kähönen, J Heinrich, AW Musk, DL Jarvis, S Gläser, MR Järvelin, BH Ch Stricker, P Elliott, GT O'Connor, DP Strachan, SJ London, IP Hall, V Gudnason, MD Tobin
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Myocardial infarction (early onset). The EFO term myocardial infarction was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
S Kathiresan, BF Voight, S Purcell, K Musunuru, D Ardissino, PM Mannucci, S Anand, JC Engert, NJ Samani, H Schunkert, J Erdmann, MP Reilly, DJ Rader, T Morgan, JA Spertus, M Stoll, D Girelli, PP McKeown, CC Patterson, DS Siscovick, CJ O'Donnell, R Elosua, L Peltonen, V Salomaa, SM Schwartz, O Melander, D Altshuler, D Ardissino, PA Merlini, C Berzuini, L Bernardinelli, F Peyvandi, M Tubaro, P Celli, M Ferrario, R Fetiveau, N Marziliano, G Casari, M Galli, F Ribichini, M Rossi, F Bernardi, P Zonzin, A Piazza, PM Mannucci, SM Schwartz, DS Siscovick, J Yee, Y Friedlander, R Elosua, J Marrugat, G Lucas, I Subirana, J Sala, R Ramos, S Kathiresan, JB Meigs, G Williams, DM Nathan, CA MacRae, CJ O'Donnell, V Salomaa, AS Havulinna, L Peltonen, O Melander, G Berglund, BF Voight, S Kathiresan, JN Hirschhorn, R Asselta, S Duga, M Spreafico, K Musunuru, MJ Daly, S Purcell, BF Voight, S Purcell, J Nemesh, JM Korn, SA McCarroll, SM Schwartz, J Yee, S Kathiresan, G Lucas, I Subirana, R Elosua, A Surti, C Guiducci, L Gianniny, D Mirel, M Parkin, N Burtt, SB Gabriel, NJ Samani, JR Thompson, PS Braund, BJ Wright, AJ Balmforth, SG Ball, A Hall, H Schunkert, J Erdmann, P Linsel-Nitschke, W Lieb, A Ziegler, I König, C Hengstenberg, M Fischer, K Stark, A Grosshennig, M Preuss, HE Wichmann, S Schreiber, H Schunkert, NJ Samani, J Erdmann, W Ouwehand, C Hengstenberg, P Deloukas, M Scholz, F Cambien, MP Reilly, M Li, Z Chen, R Wilensky, W Matthai, A Qasim, HH Hakonarson, J Devaney, MS Burnett, AD Pichard, KM Kent, L Satler, JM Lindsay, R Waksman, CW Knouff, DM Waterworth, MC Walker, V Mooser, SE Epstein, DJ Rader, T Scheffold, K Berger, M Stoll, A Huge, D Girelli, N Martinelli, O Olivieri, R Corrocher, T Morgan, JA Spertus, P McKeown, CC Patterson, H Schunkert, E Erdmann, P Linsel-Nitschke, W Lieb, A Ziegler, IR König, C Hengstenberg, M Fischer, K Stark, A Grosshennig, M Preuss, HE Wichmann, S Schreiber, H Hólm, G Thorleifsson, U Thorsteinsdottir, K Stefansson, JC Engert, R Do, C Xie, S Anand, S Kathiresan, D Ardissino, PM Mannucci, D Siscovick, CJ O'Donnell, NJ Samani, O Melander, R Elosua, L Peltonen, V Salomaa, SM Schwartz, D Altshuler
Striatum Gene Expression Correlates for ACTI20_ETHA measured in BXD RI Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The ACTI20_ETHA measures Distance traveled (cm) during the fourth five minute bin after ethanol under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for ENTRIES_OPEN measured in BXD RI Females & Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The ENTRIES_OPEN measures Number of entries into open arms of plus maze under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001.
QTL for differences in cocaine responsiveness on Chr16 at Pmv-35 (67.79 Mbp , Build 37)
Description:
differences in cocaine responsiveness spans 42.79 - 92.79 Mbp (NCBI Build 37) on Chr16. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for ethanol induced activation on Chr16 at D16Mit203 (93.93 Mbp , Build 37)
Description:
ethanol induced activation spans 68.93 - 118.93 Mbp (NCBI Build 37) on Chr16. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for body temperature on Chr16 at D16Mit70 (96.77 Mbp , Build 37)
Description:
METH responses for body temperature spans 71.77 - 121.77 Mbp (NCBI Build 37) on Chr16. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Genes associated with Homo sapiens that interact with the MeSH term 'Arsenic' (D001151). Incorporates data from 87 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Clarithromycin' (D017291). Incorporates data from 22 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Phenobarbital' (D010634). Incorporates data from 15 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Methylmercury Compounds' (D008767). Incorporates data from 137 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'E 4031' (C063968). Incorporates data from 17 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Cavia porcellus that interact with the MeSH term 'Potassium' (D011188). Incorporates data from 22 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Cyprinus carpio that interact with the MeSH term 'Propranolol' (D011433). Incorporates data from 13 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Silicon Dioxide' (D012822). Incorporates data from 9 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Acetaminophen' (D000082). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
QTL associated with cocaine induced activation 12. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (76817838)
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