List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Childhood body mass index. The EFO term body mass index was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Hippocampus Gene Expression Correlates for ZM_LATENCY measured in BXD RI Females & Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The ZM_LATENCY measures Zero Maze - Latency to enter an open quadrant under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
QTL for ethanol conditioned taste aversion on Chr3 at D3Mit11 (111.75 Mbp , Build 37)
Description:
ethanol conditioned taste aversion spans 86.75 - 136.75 Mbp (NCBI Build 37) on Chr3. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for body temperature on Chr3 at Gnat2 (111.75 Mbp , Build 37)
Description:
METH responses for body temperature spans 86.75 - 136.75 Mbp (NCBI Build 37) on Chr3. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Genes associated with Homo sapiens that interact with the MeSH term '2,2',4,4'-tetrabromodiphenyl ether' (C511295). Incorporates data from 6 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Platichthys flesus that interact with the MeSH term 'pentabromodiphenyl ether' (C086401). Incorporates data from 4 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide' (D015123). Incorporates data from 660 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'kojic acid' (C011890). Incorporates data from 5 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'kavain' (C011889). Incorporates data from 312 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Rats in separate cage with free choice of water or 10% (v/v) of ethanol; consumption scores (grams/kg/day) were averaged; the amounts of ethanol consumed were measured over 2 days. Additive QTL. Variance 18, p-value 0.00022, LOD 4.1 Peak Marker: D2Rat118 spans 192489056-237489056 Strains were WKY, HEP.
Authors:
Terenina-Rigaldie E, Moisan MP, Colas A, Beaug F, Shah KV, Jones BC, Mormde P
Ethanol Induced Hypothermia Chr# 3 rs3710548 (145932289) with right flanking marker rs3719390 (85222358) and left marker rs30801216 (156802752). This was mapped in 300 + (b6x129)F2 mice.
loss of righting reflex assay. 155,101,972 - 247,295,816 involved strains HAS.LAS-(D2Rat38-D2Rat69). intercross allele responsible: LAS allele was dominant inducing agent: intraperitoneal administration of alcohol 2.25 g/kg measurement method: after alcohol administration, animals were placed on their back and the time at when they no longer right themselves was recorded; the lapse time at which they could right themselves was taken as loss of righting reflex (LORR) Likelihood Ratio: 16.3 software package used: Map Manager QTX duration of loss of righting reflex was less in female
Authors:
Radcliffe RA, Bludeau P, Asperi W, Fay T, Deng XS, Erwin VG, Deitrich RA
QTL associated with atherosclerotic lesion area 4. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (115533310)
QTL associated with cytokine deficiency colitis susceptibility 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (126744151)
QTL associated with cystic fibrosis survival to weaning 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (100779519)
QTL associated with P. chabaudi malaria resistance QTL 4. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (127399252)
Authors:
Longley R, Smith C, Fortin A, Berghout J, McMorran B, Burgio G, Foote S, Gros P
QTL associated with experimental allergic encephalomyelitis susceptibility 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (96445337)
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