Differential gene expression of RNA-Seq data from people with a history of cocaine use vs control. Gene Symbol and p-value (unadjusted). Samples were from twenty-three hippocampi from eight people with a history of alcohol use, seven with a history of cocaine use, and eight matched control subjects.
Adolescent male Sprague-Dawley rats were either exposed to the synthetic cannabinoid WIN 55,212-2 (WIN) prior to cocaine administration or not (+/- WIN and +/- cocaine). Differential cytosolic protein expression was evaluated across all four adolescent treatment groups. Gene expression was evaluated via RNA-seq. Data available at GEO with accession number GSE134935. Data taken from Supplementary Dataset S7. Values presented are p-adjusted values.
Authors:
Maria Scherma, Johanna S Qvist, Arun Asok, Shao-Shan C Huang, Paolo Masia, Matteo Deidda, Ya B Wei, Rajesh K Soni, Walter Fratta, Paola Fadda, Eric R Kandel, Denise B Kandel, Philippe A Melas
Differentially expressed genes in male Sprague-Dawley rats (300-375 g or 250-300 g) following cocaine administration. Gene expression was evaluated via RNA-seq. Data taken from Supplemental Table S1 (associated with Fig 2. E-F and H). Values presented are p-values. Data available at GEO with accession number GSE124055.
Authors:
Ashley E Lepack, Craig T Werner, Andrew F Stewart, Sasha L Fulton, Ping Zhong, Lorna A Farrelly, Alexander C W Smith, Aarthi Ramakrishnan, Yang Lyu, Ryan M Bastle, Jennifer A Martin, Swarup Mitra, Richard M O'Connor, Zi-Jun Wang, Henrik Molina, Gustavo Turecki, Li Shen, Zhen Yan, Erin S Calipari, David M Dietz, Paul J Kenny, Ian Maze
Differentially expressed genes in male Sprague-Dawley rats (300-375 g or 250-300 g) following cocaine administration. Some animals expressed the H3.3 Q5A vector, which led to down-regulation of histone H3 glutamine 5 dopaminylation (H3Q5dop), which is involved in midbrain plasticity in response to cocaine. Gene expression was evaluated via RNA-seq. Data taken from Supplemental Table S4 (associated with Fig 2. E, G, and I). Values presented are p-values. Data available at GEO with accession number GSE124055.
Authors:
Ashley E Lepack, Craig T Werner, Andrew F Stewart, Sasha L Fulton, Ping Zhong, Lorna A Farrelly, Alexander C W Smith, Aarthi Ramakrishnan, Yang Lyu, Ryan M Bastle, Jennifer A Martin, Swarup Mitra, Richard M O'Connor, Zi-Jun Wang, Henrik Molina, Gustavo Turecki, Li Shen, Zhen Yan, Erin S Calipari, David M Dietz, Paul J Kenny, Ian Maze
Differentially expressed geens in the central amygdala (CeA) of male Sprague-Dawley rats (300-350 g prior to surgery, 325-375 g at start of self-administration) on day 2 following methamphetamine withdrawal. Gene Expression was evaluated via RNA-seq. Data taken from Supplementary Table S2. Values presented are adjusted p-values. Data available from GEO with accession number GSE111243."
Authors:
Hannah M Cates, Xuan Li, Immanuel Purushothaman, Pamela J Kennedy, Li Shen, Yavin Shaham, Eric J Nestler
Differentially expressed geens in the central amygdala (CeA) of male Sprague-Dawley rats (300-350 g prior to surgery, 325-375 g at start of self-administration) on day 35 following methamphetamine withdrawal. Gene Expression was evaluated via RNA-seq. Data taken from Supplementary Table S2. Values presented are adjusted p-values. Data available from GEO with accession number GSE111243."
Authors:
Hannah M Cates, Xuan Li, Immanuel Purushothaman, Pamela J Kennedy, Li Shen, Yavin Shaham, Eric J Nestler
Genes up-regulated in various immune cells cells present in blood from MIS-C patients compared to healthy child donors. Genes from each tab (NaïveCD8, MemoryCD8, NKcell, NaïveCD4, MemoryCD4, Treg, NaïveB, MemoryB, Monocytes, Neutrophils, cDCs, pDCs) of s3-table-S6-mmc3.xlxs were assigned a category based on their cell type (indicated by the tab name) and whether they were up or down regulated (indicated by a positive or negative value in the "avg_logFC" column, e.g. either "NaïveCD8 up" or "NaïveCD8 down" for markers present in the "NaïveCD8" tab. Note that the cut-off for differentially expressed genes was greater than absolute value of 0.5, rather than greater than absolute value of 1. Genes which exhibited decreased gene expression in all cell types in which they exhibited a change in expression
level were included in this set. 34 genes which had increased expression in some cell types and decreased expression in other cell types were excluded (HGNC:1130, HGNC:6727, HGNC:10488, HGNC:4938, HGNC:4940, HGNC:4948, HGNC:4953, HGNC:10630, HGNC:3068, HGNC:3443, HGNC:6204, HGNC:1711, HGNC:347,
HGNC:533, HGNC:537, HGNC:14130, HGNC:7082, HGNC:2771, HGNC:2479, HGNC:30239, HGNC:3288, HGNC:3796, HGNC:4638, HGNC:6153, HGNC:6175, HGNC:6408, HGNC:6860, HGNC:7406, HGNC:13880, HGNC:672, HGNC:10368, HGNC:11554, HGNC:2464, HGNC:17521). The text strings "3-Mar" and "6-Sep" present in one or more Marker columns were converted to "MAR3" and "SEPT6" respectively. Genes were entered as HGNC
IDs. 13 Markers could not be mapped at HGNC (43893, 44075, AC004865.2, AC007952.4, AC020636.1, AC020656.1, AC119396.1, AC243960.1, AC245014.3, AL360270.1, AL445524.1). The ID HGNC:32393 was not found in GeneWeaver.
Authors:
Anjali Ramaswamy, Nina N Brodsky, Tomokazu S Sumida, Michela Comi, Hiromitsu Asashima, Kenneth B Hoehn, Ningshan Li, Yunqing Liu, Aagam Shah, Neal G Ravindra, Jason Bishai, Alamzeb Khan, William Lau, Brian Sellers, Neha Bansal, Pamela Guerrerio, Avraham Unterman, Victoria Habet, Andrew J Rice, Jason Catanzaro, Harsha Chandnani, Merrick Lopez, Naftali Kaminski, Charles S Dela Cruz, John S Tsang, Zuoheng Wang, Xiting Yan, Steven H Kleinstein, David van Dijk, Richard W Pierce, David A Hafler, Carrie L Lucas
Whole Brain Gene Expression Correlates for LD_PCT_LIGHT_TIME measured in BXD RI Females obtained using INIA Brain mRNA M430 (Jun06) RMA. The LD_PCT_LIGHT_TIME measures Light-Dark Box Percentage time in light under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
alcohol preference 7 spans 13.47 - 63.47 Mbp (NCBI Build 37) on Chr7. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Bachmanov AA, Reed DR, Li X, Li S, Beauchamp GK, Tordoff MG
Genes associated with Homo sapiens that interact with the MeSH term '(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine' (C516138). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Copper Sulfate' (D019327). Incorporates data from 72 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'butyraldehyde' (C018475). Incorporates data from 7 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Parathion' (D010278). Incorporates data from 2 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide' (C459179). Incorporates data from 9 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'terbufos' (C012568). Incorporates data from 7 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Selenium Compounds' (D018036). Incorporates data from 1386 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Sodium Selenite' (D018038). Incorporates data from 10 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Valproic Acid' (D014635). Incorporates data from 1238 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Nickel' (D009532). Incorporates data from 166 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Fonofos' (D004397). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Coloring Agents' (D004396). Incorporates data from 715 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Quercetin' (D011794). Incorporates data from 6 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with nan that interact with the MeSH term 'Aluminum' (D000535). Incorporates data from 24 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
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