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QTL for activity response to ethanol on Chr1 at NA (184.43 Mbp , Build 37)
Description:
activity response to ethanol spans 159.43 - 209.43 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for activity response to ethanol on Chr2 at NA (80.10 Mbp , Build 37)
Description:
activity response to ethanol spans 55.10 - 105.10 Mbp (NCBI Build 37) on Chr2. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for activity response to ethanol on Chr2 at NA (129.21 Mbp , Build 37)
Description:
activity response to ethanol spans 104.21 - 154.21 Mbp (NCBI Build 37) on Chr2. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTLs associated with ethanol-induced activation of locomotor activity were provisionally mapped in 25 BXD (B = C57BL/6J, D = DBA/2J) recombinant inbred (RI) strains and confirmed in (DBA/2J x C57BL/6J)F2 intercross and HS (heterogeneous stock) animals. (HS strain was derived from outbreeding of C57BL/6J, DBA/2J, CBA/2J, C3H/HeJ, A/J, AKR/J, BALB/cJ, and LP/J inbred strains.) Progenitor strain DBA/2J exhibits increased activity with activity decrease over time following ethanol challenge whereas progenitor strain C57BL/6J exhibits low activity with activity increase over time. (DBA/2J x C57BL/6J)F1 hybrid animals resemble the DBA/2J response to ethanol challenge. QTLs affecting ethanol-induced locomotor activity were mapped and confirmed on mouse chromosome 2 at 62 cM-64 cM (Actre3, LOD = 9.8) 113125171-163125171, interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL associated with heart rate quantitative locus 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (128157520)
Authors:
Sugiyama F, Churchill GA, Li R, Libby LJ, Carver T, Yagami K, John SW, Paigen B
QTL associated with heart rate quantitative locus 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (56068554)
Authors:
Sugiyama F, Churchill GA, Li R, Libby LJ, Carver T, Yagami K, John SW, Paigen B
QTL associated with heart rate quantitative locus 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (92584545)
Authors:
Sugiyama F, Churchill GA, Li R, Libby LJ, Carver T, Yagami K, John SW, Paigen B
QTL associated with heart weight quantitative locus 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (73709112)
Authors:
Sugiyama F, Churchill GA, Li R, Libby LJ, Carver T, Yagami K, John SW, Paigen B
QTL associated with non-insulin-dependent diabetes mellitus 5. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (56934064)
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