List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Axial length. The EFO term axial length measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
CY Cheng, M Schache, MK Ikram, TL Young, JA Guggenheim, V Vitart, S MacGregor, VJ Verhoeven, VA Barathi, J Liao, PG Hysi, JE Bailey-Wilson, B St Pourcain, JP Kemp, G McMahon, NJ Timpson, DM Evans, GW Montgomery, A Mishra, YX Wang, JJ Wang, E Rochtchina, O Polasek, AF Wright, N Amin, EM van Leeuwen, JF Wilson, CE Pennell, CM van Duijn, PT de Jong, JR Vingerling, X Zhou, P Chen, R Li, WT Tay, Y Zheng, M Chew, KP Burdon, JE Craig, SK Iyengar, RP Igo, JH Lass, EY Chew, T Haller, E Mihailov, A Metspalu, J Wedenoja, CL Simpson, R Wojciechowski, R Höhn, A Mirshahi, T Zeller, N Pfeiffer, KJ Lackner, T Bettecken, T Meitinger, K Oexle, M Pirastu, L Portas, A Nag, KM Williams, E Yonova-Doing, R Klein, BE Klein, SM Hosseini, AD Paterson, KM Makela, T Lehtimaki, M Kahonen, O Raitakari, N Yoshimura, F Matsuda, LJ Chen, CP Pang, SP Yip, MK Yap, A Meguro, N Mizuki, H Inoko, PJ Foster, JH Zhao, E Vithana, ES Tai, Q Fan, L Xu, H Campbell, B Fleck, I Rudan, T Aung, A Hofman, AG Uitterlinden, G Bencic, CC Khor, H Forward, O Pärssinen, P Mitchell, F Rivadeneira, AW Hewitt, C Williams, BA Oostra, YY Teo, CJ Hammond, D Stambolian, DA Mackey, CC Klaver, TY Wong, SM Saw, PN Baird
Cerebellum Gene Expression Correlates for ACTI05_ETHA measured in BXD RI Males obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The ACTI05_ETHA measures Distance traveled (cm) during the first five minutes after ethanol under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for VOCA_THRESHOLD measured in BXD RI Males obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The VOCA_THRESHOLD measures Vocalization Threshold - shock intensity (mA) under the domain Stress Vocalization. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
cocaine related behavior 1 (Cocrb1) spans 79.870166 - 121.405905 Mbp (NCBI Build 37) on Chr 1. Obtained from MGI (http://www.informatics.jax.org) by searching for QTLs containing the keyword .
QTL for METH responses for body temperature on Chr1 at D1Ncvs75 (79.87 Mbp , Build 37)
Description:
METH responses for body temperature spans 54.87 - 104.87 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for chronic alcohol withdrawal severity on Chr1 at D1Mit46 (83.89 Mbp , Build 37)
Description:
chronic alcohol withdrawal severity spans 58.89 - 108.89 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Bergeson SE, Kyle Warren R, Crabbe JC, Metten P, Gene Erwin V, Belknap JK
QTL for METH responses for home cage activity on Chr1 at D1Ncvs41 (101.77 Mbp , Build 37)
Description:
METH responses for home cage activity spans 76.77 - 126.77 Mbp (NCBI Build 37) on Chr1. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL associated with activity-distance traveled 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (103894727)
QTL associated with autoimmune ovarian dysgenesis 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (109462445)
QTL associated with B.burgdorferi-associated arthritis 11. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (65896421)
Authors:
Roper RJ, Weis JJ, McCracken BA, Green CB, Ma Y, Weber KS, Fairbairn D, Butterfield RJ, Potter MR, Zachary JF, Doerge RW, Teuscher C
QTL associated with bone response to mechanical loading 8. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (78202934)
QTL associated with cyclophosphamide induced apoptosis. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (66992757)
Authors:
Bergman ML, Cilio CM, Penha-Gonalves C, Lamhamedi-Cherradi SE, Lfgren A, Colucci F, Lejon K, Garchon HJ, Holmberg D
QTL associated with cytokine deficiency colitis susceptibility 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (65899760)
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