List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Serum uric acid levels. The EFO term uric acid measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
AK Giri, P Banerjee, S Chakraborty, Y Kauser, A Undru, S Roy, V Parekatt, S Ghosh, N Tandon, D Bharadwaj
MCF-7/AdVp3000 cells are selected for adriamycin-resistance in the presence of verapimil, an ABCC1/ABCB1 inhibitor (CHEBI:9948). Overexpressed proteins were detected by 2D-PAGE/MS. Tab-delimited values represent fold change reported in Table 1. HGNC identifiers were obtained through the HGNC web interface and cross-referenced with the table. TPI1 was shown as both increased and decreased, so it was omitted from this set. The value for ABCG2 is set to be that of 14-3-3 because it was shown to be increased without quantification. Therapy:doxorubicin. Response Type:resistant.
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Uric acid levels. The EFO term uric acid measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
M Kolz, T Johnson, S Sanna, A Teumer, V Vitart, M Perola, M Mangino, E Albrecht, C Wallace, M Farrall, A Johansson, DR Nyholt, Y Aulchenko, JS Beckmann, S Bergmann, M Bochud, M Brown, H Campbell, J Connell, A Dominiczak, G Homuth, C Lamina, MI McCarthy, T Meitinger, V Mooser, P Munroe, M Nauck, J Peden, H Prokisch, P Salo, V Salomaa, NJ Samani, D Schlessinger, M Uda, U Völker, G Waeber, D Waterworth, R Wang-Sattler, AF Wright, J Adamski, JB Whitfield, U Gyllensten, JF Wilson, I Rudan, P Pramstaller, H Watkins, A Doering, HE Wichmann, TD Spector, L Peltonen, H Völzke, R Nagaraja, P Vollenweider, M Caulfield, T Illig, C Gieger
GWAS: coffee consumption, cups of coffee per day measurement
Description:
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Coffee consumption (cups per day). The EFO term coffee consumption, cups of coffee per day measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
MC Cornelis, EM Byrne, T Esko, MA Nalls, A Ganna, N Paynter, KL Monda, N Amin, K Fischer, F Renstrom, JS Ngwa, V Huikari, A Cavadino, IM Nolte, A Teumer, K Yu, P Marques-Vidal, R Rawal, A Manichaikul, MK Wojczynski, JM Vink, JH Zhao, G Burlutsky, J Lahti, V Mikkilä, RN Lemaitre, J Eriksson, SK Musani, T Tanaka, F Geller, J Luan, J Hui, R Mägi, M Dimitriou, ME Garcia, WK Ho, MJ Wright, LM Rose, PK Magnusson, NL Pedersen, D Couper, BA Oostra, A Hofman, MA Ikram, HW Tiemeier, AG Uitterlinden, FJ van Rooij, I Barroso, I Johansson, L Xue, M Kaakinen, L Milani, C Power, H Snieder, RP Stolk, SE Baumeister, R Biffar, F Gu, F Bastardot, Z Kutalik, DR Jacobs, NG Forouhi, E Mihailov, L Lind, C Lindgren, K Michaëlsson, A Morris, M Jensen, KT Khaw, RN Luben, JJ Wang, S Männistö, MM Perälä, M Kähönen, T Lehtimäki, J Viikari, D Mozaffarian, K Mukamal, BM Psaty, A Döring, AC Heath, GW Montgomery, N Dahmen, T Carithers, KL Tucker, L Ferrucci, HA Boyd, M Melbye, JL Treur, D Mellström, JJ Hottenga, I Prokopenko, A Tönjes, P Deloukas, S Kanoni, M Lorentzon, DK Houston, Y Liu, J Danesh, A Rasheed, MA Mason, AB Zonderman, L Franke, BS Kristal, J Karjalainen, DR Reed, HJ Westra, MK Evans, D Saleheen, TB Harris, G Dedoussis, G Curhan, M Stumvoll, J Beilby, LR Pasquale, B Feenstra, S Bandinelli, JM Ordovas, AT Chan, U Peters, C Ohlsson, C Gieger, NG Martin, M Waldenberger, DS Siscovick, O Raitakari, JG Eriksson, P Mitchell, DJ Hunter, P Kraft, EB Rimm, DI Boomsma, IB Borecki, RJ Loos, NJ Wareham, P Vollenweider, N Caporaso, HJ Grabe, ML Neuhouser, BH Wolffenbuttel, FB Hu, E Hyppönen, MR Järvelin, LA Cupples, PW Franks, PM Ridker, CM van Duijn, G Heiss, A Metspalu, KE North, E Ingelsson, JA Nettleton, RM van Dam, DI Chasman
GWAS: urate measurement, overweight body mass index status
Description:
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Urate levels in overweight individuals. The EFO term urate measurement, overweight body mass index status was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JE Huffman, E Albrecht, A Teumer, M Mangino, K Kapur, T Johnson, Z Kutalik, N Pirastu, G Pistis, LM Lopez, T Haller, P Salo, A Goel, M Li, T Tanaka, A Dehghan, D Ruggiero, G Malerba, AV Smith, IM Nolte, L Portas, A Phipps-Green, L Boteva, P Navarro, A Johansson, AA Hicks, O Polasek, T Esko, JF Peden, SE Harris, F Murgia, SH Wild, A Tenesa, A Tin, E Mihailov, A Grotevendt, GK Gislason, J Coresh, P D'Adamo, S Ulivi, P Vollenweider, G Waeber, S Campbell, I Kolcic, K Fisher, M Viigimaa, JE Metter, C Masciullo, E Trabetti, C Bombieri, R Sorice, A Döring, E Reischl, K Strauch, A Hofman, AG Uitterlinden, M Waldenberger, HE Wichmann, G Davies, AJ Gow, N Dalbeth, L Stamp, JH Smit, M Kirin, R Nagaraja, M Nauck, C Schurmann, K Budde, SM Farrington, E Theodoratou, A Jula, V Salomaa, C Sala, C Hengstenberg, M Burnier, R Mägi, N Klopp, S Kloiber, S Schipf, S Ripatti, S Cabras, N Soranzo, G Homuth, T Nutile, PB Munroe, N Hastie, H Campbell, I Rudan, C Cabrera, C Haley, OH Franco, TR Merriman, V Gudnason, M Pirastu, BW Penninx, H Snieder, A Metspalu, M Ciullo, PP Pramstaller, CM van Duijn, L Ferrucci, G Gambaro, IJ Deary, MG Dunlop, JF Wilson, P Gasparini, U Gyllensten, TD Spector, AF Wright, C Hayward, H Watkins, M Perola, M Bochud, WH Kao, M Caulfield, D Toniolo, H Völzke, C Gieger, A Köttgen, V Vitart
GWAS: urate measurement, underweight body mass index status
Description:
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Urate levels in lean individuals. The EFO term urate measurement, underweight body mass index status was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JE Huffman, E Albrecht, A Teumer, M Mangino, K Kapur, T Johnson, Z Kutalik, N Pirastu, G Pistis, LM Lopez, T Haller, P Salo, A Goel, M Li, T Tanaka, A Dehghan, D Ruggiero, G Malerba, AV Smith, IM Nolte, L Portas, A Phipps-Green, L Boteva, P Navarro, A Johansson, AA Hicks, O Polasek, T Esko, JF Peden, SE Harris, F Murgia, SH Wild, A Tenesa, A Tin, E Mihailov, A Grotevendt, GK Gislason, J Coresh, P D'Adamo, S Ulivi, P Vollenweider, G Waeber, S Campbell, I Kolcic, K Fisher, M Viigimaa, JE Metter, C Masciullo, E Trabetti, C Bombieri, R Sorice, A Döring, E Reischl, K Strauch, A Hofman, AG Uitterlinden, M Waldenberger, HE Wichmann, G Davies, AJ Gow, N Dalbeth, L Stamp, JH Smit, M Kirin, R Nagaraja, M Nauck, C Schurmann, K Budde, SM Farrington, E Theodoratou, A Jula, V Salomaa, C Sala, C Hengstenberg, M Burnier, R Mägi, N Klopp, S Kloiber, S Schipf, S Ripatti, S Cabras, N Soranzo, G Homuth, T Nutile, PB Munroe, N Hastie, H Campbell, I Rudan, C Cabrera, C Haley, OH Franco, TR Merriman, V Gudnason, M Pirastu, BW Penninx, H Snieder, A Metspalu, M Ciullo, PP Pramstaller, CM van Duijn, L Ferrucci, G Gambaro, IJ Deary, MG Dunlop, JF Wilson, P Gasparini, U Gyllensten, TD Spector, AF Wright, C Hayward, H Watkins, M Perola, M Bochud, WH Kao, M Caulfield, D Toniolo, H Völzke, C Gieger, A Köttgen, V Vitart
GWAS: obese body mass index status, urate measurement
Description:
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Urate levels in obese individuals. The EFO term obese body mass index status, urate measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JE Huffman, E Albrecht, A Teumer, M Mangino, K Kapur, T Johnson, Z Kutalik, N Pirastu, G Pistis, LM Lopez, T Haller, P Salo, A Goel, M Li, T Tanaka, A Dehghan, D Ruggiero, G Malerba, AV Smith, IM Nolte, L Portas, A Phipps-Green, L Boteva, P Navarro, A Johansson, AA Hicks, O Polasek, T Esko, JF Peden, SE Harris, F Murgia, SH Wild, A Tenesa, A Tin, E Mihailov, A Grotevendt, GK Gislason, J Coresh, P D'Adamo, S Ulivi, P Vollenweider, G Waeber, S Campbell, I Kolcic, K Fisher, M Viigimaa, JE Metter, C Masciullo, E Trabetti, C Bombieri, R Sorice, A Döring, E Reischl, K Strauch, A Hofman, AG Uitterlinden, M Waldenberger, HE Wichmann, G Davies, AJ Gow, N Dalbeth, L Stamp, JH Smit, M Kirin, R Nagaraja, M Nauck, C Schurmann, K Budde, SM Farrington, E Theodoratou, A Jula, V Salomaa, C Sala, C Hengstenberg, M Burnier, R Mägi, N Klopp, S Kloiber, S Schipf, S Ripatti, S Cabras, N Soranzo, G Homuth, T Nutile, PB Munroe, N Hastie, H Campbell, I Rudan, C Cabrera, C Haley, OH Franco, TR Merriman, V Gudnason, M Pirastu, BW Penninx, H Snieder, A Metspalu, M Ciullo, PP Pramstaller, CM van Duijn, L Ferrucci, G Gambaro, IJ Deary, MG Dunlop, JF Wilson, P Gasparini, U Gyllensten, TD Spector, AF Wright, C Hayward, H Watkins, M Perola, M Bochud, WH Kao, M Caulfield, D Toniolo, H Völzke, C Gieger, A Köttgen, V Vitart
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Dental caries. The EFO term dental caries was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JR Shaffer, E Feingold, X Wang, M Lee, K Tcuenco, DE Weeks, RJ Weyant, R Crout, DW McNeil, ML Marazita
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Uric acid levels. The EFO term uric acid measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
R Karns, G Zhang, G Sun, S Rao Indugula, H Cheng, D Havas-Augustin, N Novokmet, D Rudan, Z Durakovic, S Missoni, R Chakraborty, P Rudan, R Deka
MCF-7/AdVp3000 cells are selected for adriamycin-resistance in the presence of verapimil, an ABCC1/ABCB1 inhibitor (CHEBI:9948). Overexpressed proteins were detected by 2D-PAGE/MS. Tab-delimited values represent fold change reported in Table 1. HGNC identifiers were obtained through the HGNC web interface and cross-referenced with the table. TPI1 was shown as both increased and decreased, so it was omitted from this set. PRX2 was reported twice. The larger value was used. Therapy:doxorubicin. Response Type:resistant.
Gene expression changes in the post-mortem nucleus accumbens of chronic heroin abusers. Overall, little overlap in gene expression profiles was seen between the two drug-abusing cohorts: out of the approximately 39,000 transcripts investigated, the abundance of only 25 was significantly changed in both cocaine and heroin abusers, with nearly one-half of these being altered in opposite directions. 1050 Transcripts had different in abundance between the majority of heroin subjects and their matched controls.
Affymetrix oligonucleotide arrays to assess gene expression in brains of mice selectively bred for differences in acute functional tolerance to an incoordinating effect of ethanol (HAFT mice, high acute functional tolerance; LAFT mice, low acute functional tolerance)
Hippocampus Gene Expression Correlates for VONFREYTHRESHOLDMEAN measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The VONFREYTHRESHOLDMEAN measures Mechanical Sensitivity-Von Frey Threshold under the domain Pain. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for VONFREYTHRESHOLDMEAN measured in BXD RI Females & Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The VONFREYTHRESHOLDMEAN measures Mechanical Sensitivity-Von Frey Threshold under the domain Pain. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C1HCOUNT30 measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C1HCOUNT30 measures Open Field locomotion 15-30 min post cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C1HCOUNT30 measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C1HCOUNT30 measures Open Field locomotion 15-30 min post cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C1HCOUNT45 measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C1HCOUNT45 measures Open Field locomotion 30-45 min post cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C1HCOUNT60 measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C1HCOUNT60 measures Open Field locomotion 45-60 min post cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C1HCOUNT60 measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C1HCOUNT60 measures Open Field locomotion 45-60 min post cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C1HDIS30 measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C1HDIS30 measures Open Field locomotion (cm) 15-30 min post cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C1HDIS30 measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C1HDIS30 measures Open Field locomotion (cm) 15-30 min post cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Hippocampus Gene Expression Correlates for C1HDIS60 measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C1HDIS60 measures Open Field locomotion (cm) 45-60 min post cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C1HDIS60 measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C1HDIS60 measures Open Field locomotion (cm) 45-60 min post cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
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