Tier
Species
Size
Attr.
GeneSet
Tier III
26322
GS407879: Genes differentially expressed with Fentanyl in C57BL/6 J and A/J in nucleus accumbens by stain_qvalue
Figure Label:
Fentanyl_C57BL/6 J _A/J_nucleus accumbens_byStain_qvalue
Description:
The current study used two inbred mouse strains, C57BL/6 J and A/J, to investigate the genetics of behavioral responses to fentanyl. Mice were tested for conditioned place preference and fentanyl-induced locomotor activity. C57BL/6J mice formed a conditioned place preference to fentanyl injections and fentanyl increased their activity. Neither effect was noted in A/J mice. We conducted RNA-sequencing on the nucleus accumbens of mice used for fentanyl-induced locomotor activity. Surprisingly, we noted few differentially expressed genes using treatment as the main factor. However many genes differed between strains.
Authors:
Samuel J Harp, Mariangela Martini, Will Rosenow, Larry D Mesner, Hugh Johnson, Charles R Farber, Emilie F Rissman
Tier IV
5770
GS408303: Genes differentially expressed with Fentanyl in C57BL/6 J and A/J in nucleus accumbens by stain_qvalue_0.05subset
Figure Label:
Fentanyl_C57BL/6 J _A/J_nucleus accumbens_byStain_qvalue_subset
Description:
Subset dataset of differentially expressed genes at padj < 0.05 of GS407879.
Authors:
Samuel J Harp, Mariangela Martini, Will Rosenow, Larry D Mesner, Hugh Johnson, Charles R Farber, Emilie F Rissman
Tier IV
51914
GS405734: WWP1 KO vs WT
Figure Label:
WWP1
Description:
To see gene sets category
Authors:
Tier IV
23905
GS408379: Differential gene expression in nucleus accumbens somatostatin interneurons that regulate behavioral responses to cocaine in mice_pvalue
Figure Label:
Differential gene expression in nucleus accumbens somatostatin interneurons_cocaine_mice_pvalue
Description:
To characterize transcriptional alterations that cocaine induces in these cells, we perform cell type-specific RNA-sequencing on FACS-isolated nuclei of somatostatin interneurons and identified 1100 DETs enriched for processes related to neural plasticity. To profile the entire (non poly-A selected) transcriptome of NAc somatostatin interneurons, we generated a transgenic reporter line (SST-TLG498 mice) to label the nuclei of these cells with a modified form of EGFP that is retained in the nuclear membrane (EGFP-F)22, enabling their isolation from NAc dissections using FACS. We succeeded in FACS-isolating nuclei suitable for RNA-sequencing from individual SST-TLG498 mice. We proceeded with differential expression analysis of the RNA-sequencing data to identify differentially expressed transcripts (DETs) in NAc somatostatin interneurons in response to repeated cocaine exposure: 778 transcripts were upregulated by cocaine and 322 were downregulated.
Authors:
Efrain A Ribeiro, Marine Salery, Joseph R Scarpa, Erin S Calipari, Peter J Hamilton, Stacy M Ku, Hope Kronman, Immanuel Purushothaman, Barbara Juarez, Mitra Heshmati, Marie Doyle, Casey Lardner, Dominicka Burek, Ana Strat, Stephen Pirpinias, Ezekiell Mouzon, Ming-Hu Han, Rachael L Neve, Rosemary C Bagot, Andrew Kasarskis, Ja Wook Koo, Eric J Nestler
Tier IV
19215
GS406229: cc coca diffcoexp universe
Figure Label:
cc coca diffcoexp universe
Description:
cc coca diffcoexp universe
Authors:
None
Tier I
3212
GS128575: Ethanol induced LORR Chr# 2
Figure Label:
QTL-Ethanol LORR-Mouse-Chr2
Description:
Ethanol induced LORR Chr# 2 rs13476399(28144658) with right flanking marker rs3713997(3151175) and left marker rs3679483 (179861211). This was mapped in 300 + (b6x129)F2 mice.
Authors:
None
Tier II
799
GS223105: Serum triglyceride level QTL 24 (Stl24 Published QTL Chr 7)
Figure Label:
QTL-Stl24-Rat-Chr 7
Description:
QTL Associated with Lipid level. On Chromosome 7 with a LOD score= 7.1, p-value =. From a(n) intercross of
Authors:
Nobrega MA, Solberg Woods LC, Fleming S, Jacob HJ
Tier II
437
GS223142: Bone structure and strength QTL 24 (Bss24 Published QTL Chr 7)
Figure Label:
QTL-Bss24-Rat-Chr 7
Description:
QTL Associated with Bone structure. On Chromosome 7 with a LOD score= 6.71, p-value =1.00E-04. From a(n) intercross of
Authors:
Sun Q, Alam I, Liu L, Koller DL, Carr LG, Econs MJ, Foroud T, Turner CH
Tier II
921
GS223169: Blood pressure QTL 38 (Bp38 Published QTL Chr 7)
Figure Label:
QTL-Bp38-Rat-Chr 7
Description:
QTL Associated with Blood pressure. On Chromosome 7 with a LOD score= 1.6, p-value =0.052. From a(n) F2 of SS/Jr x LEW
Authors:
Garrett MR, Dene H, Walder R, Zhang QY, Cicila GT, Assadnia S, Deng AY, Rapp JP
Tier II
437
GS223269: Bone structure and strength QTL 32 (Bss32 Published QTL Chr 7)
Figure Label:
QTL-Bss32-Rat-Chr 7
Description:
QTL Associated with Bone structure. On Chromosome 7 with a LOD score= 7.64, p-value =1.00E-04. From a(n) intercross of
Authors:
Sun Q, Alam I, Liu L, Koller DL, Carr LG, Econs MJ, Foroud T, Turner CH
Tier II
373
GS223365: Blood pressure QTL 169 (Bp169 Published QTL Chr 7)
Figure Label:
QTL-Bp169-Rat-Chr 7
Description:
QTL Associated with Blood pressure. On Chromosome 7 with a LOD score= , p-value =1.00E-04. From a(n) of
Authors:
Cicila GT, Garrett MR, Lee SJ, Liu J, Dene H, Rapp JP
Tier II
449
GS223422: Blood pressure QTL 181 (Bp181 Published QTL Chr 7)
Figure Label:
QTL-Bp181-Rat-Chr 7
Description:
QTL Associated with Blood pressure. On Chromosome 7 with a LOD score= 3.36, p-value =. From a(n) of
Authors:
Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr
Tier II
371
GS223556: Estrogen-induced pituitary tumorigenesis QTL 7 (Ept7 Published QTL Chr 7)
Figure Label:
QTL-Ept7-Rat-Chr 7
Description:
QTL Associated with Gland mass. On Chromosome 7 with a LOD score= 3.7, p-value =. From a(n) of
Authors:
Shull JD, Lachel CM, Murrin CR, Pennington KL, Schaffer BS, Strecker TE, Gould KA
Tier II
799
GS223561: Renal function QTL 58 (Rf58 Published QTL Chr 7)
Figure Label:
QTL-Rf58-Rat-Chr 7
Description:
QTL Associated with Renal function. On Chromosome 7 with a LOD score= 7.8, p-value =. From a(n) intercross of
Authors:
Nobrega MA, Solberg Woods LC, Fleming S, Jacob HJ
Tier II
371
GS223692: Estrogen-induced mammary cancer QTL 4 (Emca4 Published QTL Chr 7)
Figure Label:
QTL-Emca4-Rat-Chr 7
Description:
QTL Associated with Mammary tumor susceptibility. On Chromosome 7 with a LOD score= 3.7, p-value =. From a(n) of
Authors:
Schaffer BS, Lachel CM, Pennington KL, Murrin CR, Strecker TE, Tochacek M, Gould KA, Meza JL, McComb RD, Shull JD
Tier II
437
GS223856: Bone mineral density QTL 32 (Bmd32 Published QTL Chr 7)
Figure Label:
QTL-Bmd32-Rat-Chr 7
Description:
QTL Associated with Bone mineral density. On Chromosome 7 with a LOD score= 5.1, p-value =1.00E-04. From a(n) intercross of
Authors:
Alam I, Sun Q, Liu L, Koller DL, Carr LG, Econs MJ, Foroud T, Turner CH
Tier II
672
GS223862: Stress Responsive Adrenal Weight QTL 5 (Sradr5 Published QTL Chr 7)
Figure Label:
QTL-Sradr5-Rat-Chr 7
Description:
QTL Associated with Hypothalamic-pituitary-adrenal axis. On Chromosome 7 with a LOD score= 5.55, p-value =. From a(n) of
Authors:
Solberg LC, Baum AE, Ahmadiyeh N, Shimomura K, Li R, Turek FW, Takahashi JS, Churchill GA, Redei EE
Tier II
437
GS224030: Bone mineral density QTL 21 (Bmd21 Published QTL Chr 7)
Figure Label:
QTL-Bmd21-Rat-Chr 7
Description:
QTL Associated with Bone mineral density. On Chromosome 7 with a LOD score= 4.2, p-value =3.00E-04. From a(n) intercross of
Authors:
Alam I, Sun Q, Liu L, Koller DL, Carr LG, Econs MJ, Foroud T, Turner CH
Tier II
437
GS224037: Bone mineral density QTL 29 (Bmd29 Published QTL Chr 7)
Figure Label:
QTL-Bmd29-Rat-Chr 7
Description:
QTL Associated with Bone mineral density. On Chromosome 7 with a LOD score= 5.4, p-value =1.00E-04. From a(n) intercross of
Authors:
Alam I, Sun Q, Liu L, Koller DL, Carr LG, Econs MJ, Foroud T, Turner CH
Tier II
1037
GS224058: Pain QTL 2 (Pain2 Published QTL Chr 7)
Figure Label:
QTL-Pain2-Rat-Chr 7
Description:
QTL Associated with Pain. On Chromosome 7 with a LOD score= 1, p-value =. From a(n) intercross of
Authors:
Nissenbaum J, Shpigler H, Pisanté A, DelCanho S, Minert A, Seltzer Z, Devor M, Darvasi A
Tier II
1269
GS224064: Kidney mass QTL 5 (Kidm5 Published QTL Chr 7)
Figure Label:
QTL-Kidm5-Rat-Chr 7
Description:
QTL Associated with Kidney mass. On Chromosome 7 with a LOD score= 3.51, p-value =. From a(n) of
Authors:
Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr
Tier II
1721
GS224139: Anxiety related response QTL 17 (Anxrr17 Published QTL Chr 7)
Figure Label:
QTL-Anxrr17-Rat-Chr 7
Description:
QTL Associated with Anxiety response. On Chromosome 7 with a LOD score= 3.66, p-value =. From a(n) intercross of LEW/NIcoxSHR/NIco
Authors:
Ramos A, Moisan MP, Chaouloff F, Mormède C, Mormède P
Tier II
536
GS224170: Cardiac mass QTL 6 (Cm6 Published QTL Chr 7)
Figure Label:
QTL-Cm6-Rat-Chr 7
Description:
QTL Associated with Cardiac mass. On Chromosome 7 with a LOD score= 4.09, p-value =. From a(n) of
Authors:
Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr
Tier II
437
GS224282: Bone mineral density QTL 54 (Bmd54 Published QTL Chr 7)
Figure Label:
QTL-Bmd54-Rat-Chr 7
Description:
QTL Associated with Bone mineral density. On Chromosome 7 with a LOD score= 5.3, p-value =1.00E-04. From a(n) intercross of
Authors:
Koller DL, Liu L, Alam I, Sun Q, Econs MJ, Foroud T, Turner CH
Tier II
386
GS224310: Adjuvant induced arthritis QTL 16 (Aia16 Published QTL Chr 7)
Figure Label:
QTL-Aia16-Rat-Chr 7
Description:
QTL Associated with Joint/bone inflammation. On Chromosome 7 with a LOD score= 2.71, p-value =. From a(n) intercross of
Authors:
Bleich A, Hopf S, Hedrich HJ, van Lith HA, Li F, Balfour Sartor R, Mähler M
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