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					GeneSet Title
	Tier IV	Human		0 Genes	GS400082 Upregulated: genes differentially expressed 6 hours after exposure of SH-SY5Y cells differentiated to dopaminergic neurons to 5 M cocaine
					LABEL: human cocaine 6h upreg DESCRIPTION: 420 genes that are upregulated in human SH-SY5Y cells (cultured and differentiated into dopaminergic neurons) 6 hours following exposure to 5 uM cocaine. Gene expression was assessed via microarray analysis and validated via RT-qPCR. Data taken from Supplementary Table S3. Data available at GEO with accession number GSE71939. Values presented are p-adjusted values.
	Tier IV	Human		307 Genes	GS400084 Downregulated: genes differentially expressed 6 hours after exposure of human SH-SY5Y cells differentiated to dopaminergic neurons to 5 uM cocaine (microarray)
					LABEL: human cocaine 6h downreg DESCRIPTION: 335 genes that are downregulated in human SH-SY5Y cells (cultured and differentiated into dopaminergic neurons) 6 hours following exposure to 5 uM cocaine. Gene expression was assessed via microarray analysis and validated via RT-qPCR. Data taken from Supplementary Table S3. Data available at GEO with accession number GSE71939. Values presented are p-adjusted values.
	Tier IV	Human		22 Genes	GS400086 . Predicted targets for mir-124a in the subset of up-regulated genes 6h after exposure of human SH-SY5Y cells differentiated to dopaminergic neurons to cocaine 5 uM (microarray)
					LABEL: human cocaine mir-124a targets DESCRIPTION: 23 genes that are predicted targets of miR-124a and upregulated in human SH-SY5Y cells (cultured and differentiated into dopaminergic neurons) 6 hours following exposure to cocaine. Gene expression was assessed via microarray analysis and validated via RT-qPCR. Data taken from Supplementary Table S4. Data available at GEO with accession number GSE71939. Values presented are "1" for presence.

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Supported by NIH R01 AA18776 jointly funded by NIAAA and NIDA, and JAX Center for Precision Genetics NIH U54 OD 020351