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LABEL: Up-regulated Immune genes in chicken DESCRIPTION: One day old specific pathogen-free White Leghorn chicks were intra-nasally inoculated with Avian infectious bronchitis virus (IBV). Total RNA was extracted from of uninfected birds or those that died from IBV infection. Samples were hybridized to a Agilent custom checken oligo microarray. The GO category for biological process and KEGG pathway analysis for carried out for differentially expressed (DE) genes, and P value < 0.05 and a FDR of < 0.05 was used as a threshold. The DE genes mainly clustered into 12 functional groups. Here genes up-regulated that are associated with innate immune response are shown. Genes were considered to be significantly u--regulated or down-regulated if the change in their relative expression levels was > 2-fold or < 2-fold. The following gene symbols were not annotated in this gene set as they were not found in GeneWeaver IL1R1, JUN, DUSP4, VNN1, TLR4 and C1R.
LABEL: Down-regulated Immune genes in chicken DESCRIPTION: One day old specific pathogen-free White Leghorn chicks were intra-nasally inoculated with Avian infectious bronchitis virus (IBV). Total RNA was extracted from of uninfected birds or those that died from IBV infection. Samples were hybridized to a Agilent custom checken oligo microarray. The GO category for biological process and KEGG pathway analysis for carried out for differentially expressed (DE) genes, and P value < 0.05 and a FDR of < 0.05 was used as a threshold. The DE genes mainly clustered into 12 functional groups. Here genes down-regulated that are associated with innate immune response are shown. Genes were considered to be significantly up--regulated or down-regulated if the change in their relative expression levels was > 2-fold or < 2-fold. The gene MASP1 was not included in this gene set as the id was not found by GeneWeaver.
LABEL: Up-regulated Cytokine genes in chicken DESCRIPTION: One day old specific pathogen-free White Leghorn chicks were intra-nasally inoculated with Avian infectious bronchitis virus (IBV). Total RNA was extracted from of uninfected birds or those that died from IBV infection. Samples were hybridized to a Agilent custom checken oligo microarray. The GO category for biological process and KEGG pathway analysis for carried out for differentially expressed (DE) genes, and P value < 0.05 and a FDR of < 0.05 was used as a threshold. The DE genes mainly clustered into 12 functional groups. Here genes up-regulated that are associated with the cytokine-mediated signalling pathway are shown. Genes were considered to be significantly up--regulated or down-regulated if the change in their relative expression levels was > 2-fold or < 2-fold. GeneWeaver did not find ids for the following genes which were consequentially not included, IFI35, PML and IRF1.
LABEL: Down-regulated Cytokine genes in chicken DESCRIPTION: One day old specific pathogen-free White Leghorn chicks were intra-nasally inoculated with Avian infectious bronchitis virus (IBV). Total RNA was extracted from of uninfected birds or those that died from IBV infection. Samples were hybridized to a Agilent custom checken oligo microarray. The GO category for biological process and KEGG pathway analysis for carried out for differentially expressed (DE) genes, and P value < 0.05 and a FDR of < 0.05 was used as a threshold. The DE genes mainly clustered into 12 functional groups. Here genes down-regulated that are associated with the cytokine-mediated signalling pathway are shown. Genes were considered to be significantly up--regulated or down-regulated if the change in their relative expression levels was > 2-fold or < 2-fold.
LABEL: Up-regulated Inflamatory response genes involved in response to Coronovirus avian infectious bronchitis infection in chicken kidney DESCRIPTION: One day old specific pathogen-free White Leghorn chicks were intra-nasally inoculated with Avian infectious bronchitis virus (IBV). Total RNA was extracted from of uninfected birds or those that died from IBV infection. Samples were hybridized to a Agilent custom checken oligo microarray. The GO category for biological process and KEGG pathway analysis for carried out for differentially expressed (DE) genes, and P value < 0.05 and a FDR of < 0.05 was used as a threshold. The DE genes mainly clustered into 12 functional groups. Here genes up-regulated that are associated with Inflamatory response are shown. Genes were considered to be significantly up--regulated or down-regulated if the change in their relative expression levels was > 2-fold or < 2-fold. The following genes werre not included in this gene set as GeneWeaver did not find their ids SCG2, S100A9, VNN1 and CCL17.
LABEL: Down-regulated Inflamatory response genes in chicken DESCRIPTION: One day old specific pathogen-free White Leghorn chicks were intra-nasally inoculated with Avian infectious bronchitis virus (IBV). Total RNA was extracted from of uninfected birds or those that died from IBV infection. Samples were hybridized to a Agilent custom checken oligo microarray. The GO category for biological process and KEGG pathway analysis for carried out for differentially expressed (DE) genes, and P value < 0.05 and a FDR of < 0.05 was used as a threshold. The DE genes mainly clustered into 12 functional groups. Here genes down-regulated that are associated with Inflamatory response s are shown. Genes were considered to be significantly up--regulated or down-regulated if the change in their relative expression levels was > 2-fold or < 2-fold. Note that GeneWeaver did not find the id for gene SERPINA1, and consequently this gene was not loaded in this gene set.