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					GeneSet Title
	Tier III	Rat		26 Genes	GS37152 Upregulated genes in hepatocytes, one month after chronic ethanol 13/g/kg/d
					LABEL: EtOH upregulation DESCRIPTION: Bolus fed rats (6g/kg/body weight, 20% ethanol solution) or rats maintained on an intragatric liquid ethanol diet (13/g/kg/d) for a month were compared with controls. Bolus fed rats were killed 3 or 12 hours post alcohol, with alcohol and blood levels taken. Ethanol fed rats were killed at either peak or trough of the urinary alcohol cycle (UAL). Data set is comparison of the experimental group versus control during peak UAL in hepatocytes.
	Tier III	Rat		5 Genes	GS37165 Downregulated genes in hepatocytes, one month after chronic ethanol 13/g/kg/d
					LABEL: EtOH Downregulation DESCRIPTION: Bolus fed rats (6g/kg/body weight, 20% ethanol solution) or rats maintained on an intragatric liquid ethanol diet (13/g/kg/d) for a month were compared with controls. Bolus fed rats were killed 3 or 12 hours post alcohol, with alcohol and blood levels taken. Ethanol fed rats were killed at either peak or trough of the urinary alcohol cycle (UAL). Data set is comparison of the experimental group versus control during peak UAL in hepatocytes.
	Tier III	Rat		13 Genes	GS37166 Upregulated genes in hepatocytes, one month after chronic ethanol 13/g/kg/d
					LABEL: EtOH upregulation DESCRIPTION: Bolus fed rats (6g/kg/body weight, 20% ethanol solution) or rats maintained on an intragatric liquid ethanol diet (13/g/kg/d) for a month were compared with controls. Bolus fed rats were killed 3 or 12 hours post alcohol, with alcohol and blood levels taken. Ethanol fed rats were killed at either peak or trough of the urinary alcohol cycle (UAL). Data set is comparison of the experimental group versus control during trough UAL in hepatocytes.
	Tier III	Rat		5 Genes	GS37168 Downregulated genes in hepatocytes, one month after chronic ethanol 13/g/kg/d
					LABEL: EtOH downregulation DESCRIPTION: Bolus fed rats (6g/kg/body weight, 20% ethanol solution) or rats maintained on an intragatric liquid ethanol diet (13/g/kg/d) for a month were compared with controls. Bolus fed rats were killed 3 or 12 hours post alcohol, with alcohol and blood levels taken. Ethanol fed rats were killed at either peak or trough of the urinary alcohol cycle (UAL). Data set is comparison of the experimental group versus control during trough UAL in hepatocytes.
	Tier III	Rat		4 Genes	GS37170 Upregulated genes in hepatocytes, 3 hours after 6g/kg ethanol.
					LABEL: 3 Hours after EtOH bolus DESCRIPTION: Bolus fed rats (6g/kg/body weight, 20% ethanol solution) or rats maintained on an intragatric liquid ethanol diet (13/g/kg/d) for a month were compared with controls. Bolus fed rats were killed 3 or 12 hours post alcohol, with alcohol and blood levels taken. Ethanol fed rats were killed at either peak or trough of the urinary alcohol cycle (UAL). Data set is comparison of the experimental group versus control, 3 hours after ethanol bolus.
	Tier III	Rat		7 Genes	GS37173 Upregulated genes in hepatocytes, 12 hours after 6g/kg ethanol
					LABEL: 12 Hrs after EtOH bolus DESCRIPTION: Bolus fed rats (6g/kg/body weight, 20% ethanol solution) or rats maintained on an intragatric liquid ethanol diet (13/g/kg/d) for a month were compared with controls. Bolus fed rats were killed 3 or 12 hours post alcohol, with alcohol and blood levels taken. Ethanol fed rats were killed at either peak or trough of the urinary alcohol cycle (UAL). Data set is comparison of the experimental group versus control, 12 hours after ethanol bolus.
	Tier V	Rat		2 Genes	GS37174 Downregulated genes in hepatocytes, 12 hours after 6g/kg ethanol
					LABEL: 12 Hrs after EtOH bolus DESCRIPTION: Bolus fed rats (6g/kg/body weight, 20% ethanol solution) or rats maintained on an intragatric liquid ethanol diet (13/g/kg/d) for a month were compared with controls. Bolus fed rats were killed 3 or 12 hours post alcohol, with alcohol and blood levels taken. Ethanol fed rats were killed at either peak or trough of the urinary alcohol cycle (UAL). Data set is comparison of the experimental group versus control, 12 hours after ethanol bolus.

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Supported by NIH R01 AA18776 jointly funded by NIAAA and NIDA, and JAX Center for Precision Genetics NIH U54 OD 020351