DESCRIPTION:

RNA-seq of adult ventral stratum of naive selected lines (SOT and NOT). ~1800 genes differentially expressed p adjusted <0.05 between SOT and NOT.

LABEL:

Ventral Striaum SOT vs NOT

SCORE TYPE:

Q-Value

THRESHOLD:

<= 0.5

GENES IN THRESHOLD:

1794

DATE ADDED:

2021-11-02

DATE UPDATED:

2024-10-22

SPECIES:

AUTHORS:

Laura B Kozell, Denesa Lockwood, Priscila Darakjian, Stephanie Edmunds, Karen Shepherdson, Kari J Buck, Robert Hitzemann

TITLE:

RNA-Seq Analysis of Genetic and Transcriptome Network Effects of Dual-Trait Selection for Ethanol Preference and Withdrawal Using SOT and NOT Genetic Models.

JOURNAL:

Alcoholism, clinical and experimental research 04 2020, Vol 44, pp. 820-830

ABSTRACT:

Genetic factors significantly affect alcohol consumption and vulnerability to withdrawal. Furthermore, some genetic models showing predisposition to severe withdrawal are also predisposed to low ethanol (EtOH) consumption and vice versa, even when tested independently in naïve animals. PUBMED: 32090358
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