GeneSet Information

Tier IV GS399948 • 401 predicted gene targets of miR-124 (upregulated in human cocaine use disorder) based on GO analysis

from Publication Assignment: 471

DESCRIPTION:

401 predicted targets of miR-124, which is one of the miRNAs shown to be upregulated in female humans with cocaine use disorder. miRNA expression was determined via qPCR, and predicted targets were determined via gene ontology (GO) analysis. Values presented are "1" for presence. Data taken from Supplementary material 1.

LABEL:

Human cocaine miR-124 targets

SCORE TYPE:

Binary

DATE ADDED:

2021-06-21

DATE UPDATED:

2021-07-20

SPECIES:

AUTHORS:

Thiago Wendt Viola, Bernardo Aguzzoli Heberle, Aline Zaparte, Breno Sanvicente-Vieira, Leonardo Mendes Wainer, Gabriel Rodrigo Fries, Consuelo Walss-Bass, Rodrigo Grassi-Oliveira

TITLE:

Peripheral blood microRNA levels in females with cocaine use disorder.

JOURNAL:

Journal of psychiatric research 07 2019, Vol 114, pp. 48-54

ABSTRACT:

There is growing emphasis in the field of psychiatry on the need to identify candidate biomarkers to aid in diagnosis and clinical management of addictive disorders. MicroRNAs (miRNAs) are small nucleotide sequences with the ability to regulate gene expression at the transcriptomic level. However, the role of miRNAs as potential biomarkers for addiction is still underexplored. Based on translational and clinical findings, we compared the expression levels of microRNA-124 (miR-124), microRNA-181 (miR-181), and microRNA-212 (miR-212) between a group of females with cocaine use disorder (CUD; n = 30) and a group of healthy female controls (HC; n = 20). PUBMED: 31026664
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Annotation Information



response to cocaine trait (VT:0010718)
response to addictive substance trait (VT:0010488)
response to xenobiotic stimulus trait (VT:0010487)
organism trait (VT:0010454)

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