GeneSet Information

Tier I GS373831 • GO:0006915 apoptotic process

DESCRIPTION:

Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "apoptotic process", which is defined as "A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.12.

LABEL:

GO:0006915

SCORE TYPE:

Binary

DATE ADDED:

2020-04-02

DATE UPDATED:

2024-04-25

SPECIES:

AUTHORS:

M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock

TITLE:

Gene ontology: tool for the unification of biology. The Gene Ontology Consortium.

JOURNAL:

Nature genetics May 2000, Vol 25, pp. 25-9

Annotation Information

No sequence read archive data associated with this GeneSet.


apoptosis (GO:0006915)

Gene List • 848 Genes

Uploaded As Gene Symbol Homology Score Priority LinkOuts Emphasis