DESCRIPTION:
The effect of down-regulation of APC (Adenomatous Polyposis Coli) was studied in breast cancer cells derived from mice heterozygous for Apc<Min> (MGI:1856318) crossed to the Polyoma middle T antigen (MGI:2679595) transgenic model. These tumors are resistant to cisplatin and doxorubicin.
LABEL:
downregulated in APC mutant breast cancer
SCORE TYPE:
Binary
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