GeneSet Information

Tier III GS352594 • Genes downregulated in CXCR4-mediated resistance to cisplatin in TNBC

DESCRIPTION:

This set describes genes that are upregulated in the MDA-MB-231 cell line that has been silenced for CXCR4 and treated with cisplatin. These cells are more sensitive to cisplatin than the parental line. This result was confirmed in MDA-MB-468 cells transfected with CXCR4. The caspase 3 result represents cleaved caspase 3.

LABEL:

downregulated in CXCR4-mediated cisplatin resistance

SCORE TYPE:

Binary

DATE ADDED:

2018-04-12

DATE UPDATED:

2024-10-22

SPECIES:

AUTHORS:

None

TITLE:

None

JOURNAL:

None

Annotation Information

No sequence read archive data associated with this GeneSet.


cisplatin (CHEBI:27899)
Breast carcinoma (HP:0003002)
protein expression level evidence (ECO:0000046)
triple-receptor negative breast cancer (DOID:0060081)

Gene List • 2 Genes

Uploaded As Gene Symbol Homology Score Priority LinkOuts Emphasis