GeneSet Information

Tier I GS343461 • GO:0070822 Sin3-type complex

DESCRIPTION:

Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "Sin3-type complex", which is defined as "Any of a number of evolutionarily conserved histone deacetylase complexes (HDACs) containing a core consisting of a paired amphipathic helix motif protein (e.g. Sin3p in S. cerevisiae, Pst1 in S. pombe or Sin3A in mammals) at least one class I histone deacetylase (e.g. Rpd3p in S. cerevisiae, Clr6 in S. pombe, or HDAC1 and HDAC2 in mammals), and at least one WD40 repeat protein (e.g. Ume1p in S. cerevisiae, Prw1 in S. pombe, or RbAp46 and RbAp48 in mammals). These complexes also contain a variable number of other proteins that direct histone binding, DNA binding, or add other functionality to the complex." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.

LABEL:

GO:0070822

SCORE TYPE:

Binary

DATE ADDED:

2018-03-30

DATE UPDATED:

2020-05-06

SPECIES:

AUTHORS:

M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock

TITLE:

Gene ontology: tool for the unification of biology. The Gene Ontology Consortium.

JOURNAL:

Nature genetics May 2000, Vol 25, pp. 25-9

Annotation Information

No sequence read archive data associated with this GeneSet.


Sin3-type complex (GO:0070822)

Gene List • 11 Genes

Uploaded As Gene Symbol Homology Score Priority LinkOuts Emphasis