GeneSet Information

Tier I GS319866 • GO:0070976 TIR domain binding

DESCRIPTION:

Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "TIR domain binding", which is defined as "Interacting selectively and non-covalently with a Toll-Interleukin receptor (TIR) domain of a protein. The TIR domain is an intracellular 200 residue domain that is found in the Toll protein, the interleukin-1 receptor (IL-1R), and MyD88; it contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.

LABEL:

GO:0070976

SCORE TYPE:

Binary

DATE ADDED:

2018-03-30

DATE UPDATED:

2024-04-25

SPECIES:

AUTHORS:

M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock

TITLE:

Gene ontology: tool for the unification of biology. The Gene Ontology Consortium.

JOURNAL:

Nature genetics May 2000, Vol 25, pp. 25-9

Annotation Information

No sequence read archive data associated with this GeneSet.


TIR domain binding (GO:0070976)

Gene List • 1 Genes

Uploaded As Gene Symbol Homology Score Priority LinkOuts Emphasis