GeneSet Information

Tier I GS306779 • GO:0071159 NF-kappaB complex

DESCRIPTION:

Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "NF-kappaB complex", which is defined as "A protein complex that consists of a homo- or heterodimer of members of a family of structurally related proteins that contain a conserved N-terminal region called the Rel homology domain (RHD). In the nucleus, NF-kappaB complexes act as transcription factors. In unstimulated cells, NF-kappaB dimers are sequestered in the cytoplasm by IkappaB monomers; signals that induce NF-kappaB activity cause degradation of IkappaB, allowing NF-kappaB dimers to translocate to the nucleus and induce gene expression." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.

LABEL:

GO:0071159

SCORE TYPE:

Binary

DATE ADDED:

2018-03-30

DATE UPDATED:

2024-04-25

SPECIES:

AUTHORS:

M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock

TITLE:

Gene ontology: tool for the unification of biology. The Gene Ontology Consortium.

JOURNAL:

Nature genetics May 2000, Vol 25, pp. 25-9

Annotation Information

No sequence read archive data associated with this GeneSet.


NF-kappaB complex (GO:0071159)

Gene List • 2 Genes

Uploaded As Gene Symbol Homology Score Priority LinkOuts Emphasis