GeneSet Information

Tier V GS272097 • GO:1990712

DESCRIPTION:

"A protein complex containing at least HFE and a transferrin receptor (either TFR1/TFRC or TFR2), proposed to play a role in the sensing of transferrin-bound Fe (Fe2-Tf) on the plasma membrane to regulate hepcidin transcription." [GOC:BHF, GOC:kom, PMID:25147378]

LABEL:

GO:1990712

SCORE TYPE:

Binary

DATE ADDED:

2017-09-10

DATE UPDATED:

2024-04-25

SPECIES:

AUTHORS:

Muckenthaler MU

TITLE:

How mutant HFE causes hereditary hemochromatosis.

JOURNAL:

Blood Aug 2014, Vol 124, pp. 1212-3

Annotation Information

No sequence read archive data associated with this GeneSet.


No annotations are associated with this GeneSet.

Gene List • 7 Genes

Uploaded As Gene Symbol Homology Score Priority LinkOuts Emphasis