DESCRIPTION:

List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Ankle-brachial index. The EFO term ankle brachial index was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.

LABEL:

GWAS: ankle brachial index

SCORE TYPE:

P-Value

DATE ADDED:

2017-05-02

DATE UPDATED:

2024-09-27

SPECIES:

AUTHORS:

JM Murabito, CC White, M Kavousi, YV Sun, MF Feitosa, V Nambi, C Lamina, A Schillert, S Coassin, JC Bis, L Broer, DC Crawford, N Franceschini, R Frikke-Schmidt, M Haun, S Holewijn, JE Huffman, SJ Hwang, S Kiechl, B Kollerits, ME Montasser, IM Nolte, ME Rudock, A Senft, A Teumer, P van der Harst, V Vitart, LL Waite, AR Wood, CL Wassel, DM Absher, MA Allison, N Amin, A Arnold, FW Asselbergs, Y Aulchenko, S Bandinelli, M Barbalic, M Boban, K Brown-Gentry, DJ Couper, MH Criqui, A Dehghan, M den Heijer, B Dieplinger, J Ding, M Dörr, C Espinola-Klein, SB Felix, L Ferrucci, AR Folsom, G Fraedrich, Q Gibson, R Goodloe, G Gunjaca, M Haltmayer, G Heiss, A Hofman, A Kieback, LA Kiemeney, I Kolcic, IJ Kullo, SB Kritchevsky, KJ Lackner, X Li, W Lieb, K Lohman, C Meisinger, D Melzer, ER Mohler, I Mudnic, T Mueller, G Navis, F Oberhollenzer, JW Olin, J O'Connell, CJ O'Donnell, W Palmas, BW Penninx, A Petersmann, O Polasek, BM Psaty, B Rantner, K Rice, F Rivadeneira, JI Rotter, A Seldenrijk, M Stadler, M Summerer, T Tanaka, A Tybjaerg-Hansen, AG Uitterlinden, WH van Gilst, SH Vermeulen, SH Wild, PS Wild, J Willeit, T Zeller, T Zemunik, L Zgaga, TL Assimes, S Blankenberg, E Boerwinkle, H Campbell, JP Cooke, J de Graaf, D Herrington, SL Kardia, BD Mitchell, A Murray, T Münzel, AB Newman, BA Oostra, I Rudan, AR Shuldiner, H Snieder, CM van Duijn, U Völker, AF Wright, HE Wichmann, JF Wilson, JC Witteman, Y Liu, C Hayward, IB Borecki, A Ziegler, KE North, LA Cupples, F Kronenberg

TITLE:

Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies.

JOURNAL:

Circulation. Cardiovascular genetics Feb 2012, Vol 5, pp. 100-12

ABSTRACT:

Genetic determinants of peripheral arterial disease (PAD) remain largely unknown. To identify genetic variants associated with the ankle-brachial index (ABI), a noninvasive measure of PAD, we conducted a meta-analysis of genome-wide association study data from 21 population-based cohorts. PUBMED: 22199011
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