DESCRIPTION:

List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Neuroticism. The EFO term neuroticism measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.

LABEL:

GWAS: neuroticism measurement

SCORE TYPE:

P-Value

THRESHOLD:

<= 0.05

GENES IN THRESHOLD:

10

DATE ADDED:

2017-05-02

DATE UPDATED:

2024-10-22

SPECIES:

AUTHORS:

MH de Moor, SM van den Berg, KJ Verweij, RF Krueger, M Luciano, A Arias Vasquez, LK Matteson, J Derringer, T Esko, N Amin, SD Gordon, NK Hansell, AB Hart, I Seppälä, JE Huffman, B Konte, J Lahti, M Lee, M Miller, T Nutile, T Tanaka, A Teumer, A Viktorin, J Wedenoja, GR Abecasis, DE Adkins, A Agrawal, J Allik, K Appel, TB Bigdeli, F Busonero, H Campbell, PT Costa, G Davey Smith, G Davies, H de Wit, J Ding, BE Engelhardt, JG Eriksson, IO Fedko, L Ferrucci, B Franke, I Giegling, R Grucza, AM Hartmann, AC Heath, K Heinonen, AK Henders, G Homuth, JJ Hottenga, WG Iacono, J Janzing, M Jokela, R Karlsson, JP Kemp, MG Kirkpatrick, A Latvala, T Lehtimäki, DC Liewald, PA Madden, C Magri, PK Magnusson, J Marten, A Maschio, SE Medland, E Mihailov, Y Milaneschi, GW Montgomery, M Nauck, KG Ouwens, A Palotie, E Pettersson, O Polasek, Y Qian, L Pulkki-Råback, OT Raitakari, A Realo, RJ Rose, D Ruggiero, CO Schmidt, WS Slutske, R Sorice, JM Starr, B St Pourcain, AR Sutin, NJ Timpson, H Trochet, S Vermeulen, E Vuoksimaa, E Widen, J Wouda, MJ Wright, L Zgaga, D Porteous, A Minelli, AA Palmer, D Rujescu, M Ciullo, C Hayward, I Rudan, A Metspalu, J Kaprio, IJ Deary, K Räikkönen, JF Wilson, L Keltikangas-Järvinen, LJ Bierut, JM Hettema, HJ Grabe, CM van Duijn, DM Evans, D Schlessinger, NL Pedersen, A Terracciano, M McGue, BW Penninx, NG Martin, DI Boomsma

TITLE:

Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder.

JOURNAL:

JAMA psychiatry Jul 2015, Vol 72, pp. 642-50

ABSTRACT:

Neuroticism is a pervasive risk factor for psychiatric conditions. It genetically overlaps with major depressive disorder (MDD) and is therefore an important phenotype for psychiatric genetics. The Genetics of Personality Consortium has created a resource for genome-wide association analyses of personality traits in more than 63,000 participants (including MDD cases). PUBMED: 25993607
Find other GeneSets from this publication