DESCRIPTION:

List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was C-reactive protein. The EFO term C-reactive protein measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.

LABEL:

GWAS: C-reactive protein measurement

SCORE TYPE:

P-Value

DATE ADDED:

2017-05-02

DATE UPDATED:

2024-04-25

SPECIES:

AUTHORS:

P Elliott, JC Chambers, W Zhang, R Clarke, JC Hopewell, JF Peden, J Erdmann, P Braund, JC Engert, D Bennett, L Coin, D Ashby, I Tzoulaki, IJ Brown, S Mt-Isa, MI McCarthy, L Peltonen, NB Freimer, M Farrall, A Ruokonen, A Hamsten, N Lim, P Froguel, DM Waterworth, P Vollenweider, G Waeber, MR Jarvelin, V Mooser, J Scott, AS Hall, H Schunkert, SS Anand, R Collins, NJ Samani, H Watkins, JS Kooner

TITLE:

Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease.

JOURNAL:

JAMA Jul 2009, Vol 302, pp. 37-48

ABSTRACT:

Plasma levels of C-reactive protein (CRP) are independently associated with risk of coronary heart disease, but whether CRP is causally associated with coronary heart disease or merely a marker of underlying atherosclerosis is uncertain. PUBMED: 19567438
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