DESCRIPTION:

List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Major depressive disorder. The EFO term unipolar depression was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.

LABEL:

GWAS: unipolar depression

SCORE TYPE:

P-Value

DATE ADDED:

2017-05-02

DATE UPDATED:

2024-04-25

SPECIES:

AUTHORS:

M Rietschel, M Mattheisen, J Frank, J Treutlein, F Degenhardt, R Breuer, M Steffens, D Mier, C Esslinger, H Walter, P Kirsch, S Erk, K Schnell, S Herms, HE Wichmann, S Schreiber, KH Jöckel, J Strohmaier, D Roeske, B Haenisch, M Gross, S Hoefels, S Lucae, EB Binder, TF Wienker, TG Schulze, C Schmäl, A Zimmer, D Juraeva, B Brors, T Bettecken, A Meyer-Lindenberg, B Müller-Myhsok, W Maier, MM Nöthen, S Cichon

TITLE:

Genome-wide association-, replication-, and neuroimaging study implicates HOMER1 in the etiology of major depression.

JOURNAL:

Biological psychiatry Sep 2010, Vol 68, pp. 578-85

ABSTRACT:

Genome-wide association studies are a powerful tool for unravelling the genetic background of complex disorders such as major depression. PUBMED: 20673876
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